Compile Data Set for Download or QSAR
maximum 50k data
Found 20 of affinity data for UniProtKB/TrEMBL: P07379
TargetPhosphoenolpyruvate carboxykinase, cytosolic [GTP](Rattus norvegicus (Rat))
The University Of Kansas Medical Center

LigandPNGBDBM181109(3-Mercaptopicolinic acid (MPA))
Affinity DataKi:  3.70E+4nM ΔG°:  -25.3kJ/moleT: 2°CAssay Description:OAA/PEP binding site. When the enzyme was assayed in the direction of PEP →OAA, the standard reaction mixture contained 50 mM HEPES (pH 7.5), 2...More data for this Ligand-Target Pair
TargetPhosphoenolpyruvate carboxykinase, cytosolic [GTP] [H477R](Rattus norvegicus (Rat))
University Of Waterloo

LigandPNGBDBM223201(β-Sulfopyruvate)
Affinity DataKi:  3.70E+4nMAssay Description:The inhibition of H477R PEPCK by β-sulfopyruvate (βSP), oxalate, and GMPPCP was conducted in the direction of PEP synthesis (OAA → PE...More data for this Ligand-Target Pair
TargetPhosphoenolpyruvate carboxykinase, cytosolic [GTP](Rattus norvegicus (Rat))
The University Of Kansas Medical Center

LigandPNGBDBM181109(3-Mercaptopicolinic acid (MPA))
Affinity DataKi:  4.50E+4nM ΔG°:  -24.8kJ/moleT: 2°CAssay Description:OAA/PEP binding site. The activity of PEPCK in the direction from OAA to PEP was assayed with 50 mM HEPES (pH 7.5), 10 mM DTT, 4 mM MgCl2, 0.5 mM GTP...More data for this Ligand-Target Pair
TargetPhosphoenolpyruvate carboxykinase, cytosolic [GTP](Rattus norvegicus (Rat))
The University Of Kansas Medical Center

LigandPNGBDBM181109(3-Mercaptopicolinic acid (MPA))
Affinity DataKi:  8.30E+4nM ΔG°:  -23.3kJ/moleT: 2°CAssay Description:Allosteric binding site. When the enzyme was assayed in the direction of PEP →OAA, the standard reaction mixture contained 50 mM HEPES (pH 7.5)...More data for this Ligand-Target Pair
TargetPhosphoenolpyruvate carboxykinase, cytosolic [GTP](Rattus norvegicus (Rat))
The University Of Kansas Medical Center

LigandPNGBDBM181109(3-Mercaptopicolinic acid (MPA))
Affinity DataKi:  8.30E+4nM ΔG°:  -23.3kJ/moleT: 2°CAssay Description:OAA/PEP binding site. When the enzyme was assayed in the direction of PEP →OAA, the standard reaction mixture contained 50 mM HEPES (pH 7.5), 2...More data for this Ligand-Target Pair
TargetPhosphoenolpyruvate carboxykinase, cytosolic [GTP](Rattus norvegicus (Rat))
The University Of Kansas Medical Center

LigandPNGBDBM181109(3-Mercaptopicolinic acid (MPA))
Affinity DataKi:  1.21E+5nM ΔG°:  -22.4kJ/moleT: 2°CAssay Description:Allosteric binding site. The activity of PEPCK in the direction from OAA to PEP was assayed with 50 mM HEPES (pH 7.5), 10 mM DTT, 4 mM MgCl2, 0.5 mM ...More data for this Ligand-Target Pair
TargetPhosphoenolpyruvate carboxykinase, cytosolic [GTP](Rattus norvegicus (Rat))
The University Of Kansas Medical Center

LigandPNGBDBM223202(β,γ-methyleneguanosine 5′-triphosp...)
Affinity DataKi:  1.50E+5nMAssay Description:The inhibition of H477R PEPCK by β-sulfopyruvate (βSP), oxalate, and GMPPCP was conducted in the direction of PEP synthesis (OAA → PE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphoenolpyruvate carboxykinase, cytosolic [GTP](Rattus norvegicus (Rat))
The University Of Kansas Medical Center

LigandPNGBDBM181109(3-Mercaptopicolinic acid (MPA))
Affinity DataKi:  1.80E+5nM ΔG°:  -21.4kJ/moleT: 2°CAssay Description:Allosteric binding site. When the enzyme was assayed in the direction of PEP →OAA, the standard reaction mixture contained 50 mM HEPES (pH 7.5)...More data for this Ligand-Target Pair
TargetPhosphoenolpyruvate carboxykinase, cytosolic [GTP] [H477R](Rattus norvegicus (Rat))
University Of Waterloo

LigandPNGBDBM50366413(PHOSPHOENOLPYRUVATE)
Affinity DataKi:  2.89E+5nMAssay Description:The inhibition of H477R PEPCK by β-sulfopyruvate (βSP), oxalate, and GMPPCP was conducted in the direction of PEP synthesis (OAA → PE...More data for this Ligand-Target Pair
TargetPhosphoenolpyruvate carboxykinase, cytosolic [GTP] [H477R](Rattus norvegicus (Rat))
University Of Waterloo

LigandPNGBDBM23230(2-Oxosuccinic acid | 2-oxobutanedioic acid | Oxalo...)
Affinity DataKi:  4.41E+5nMAssay Description:The inhibition of H477R PEPCK by β-sulfopyruvate (βSP), oxalate, and GMPPCP was conducted in the direction of PEP synthesis (OAA → PE...More data for this Ligand-Target Pair
TargetPhosphoenolpyruvate carboxykinase, cytosolic [GTP] [H477R](Rattus norvegicus (Rat))
University Of Waterloo

LigandPNGBDBM223202(β,γ-methyleneguanosine 5′-triphosp...)
Affinity DataKi:  6.96E+5nMAssay Description:The inhibition of H477R PEPCK by β-sulfopyruvate (βSP), oxalate, and GMPPCP was conducted in the direction of PEP synthesis (OAA → PE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphoenolpyruvate carboxykinase, cytosolic [GTP](Rattus norvegicus (Rat))
The University Of Kansas Medical Center

LigandPNGBDBM50133801(CHEMBL120708 | N-(4-((1-(2-fluorobenzyl)-3-butyl-2...)
Affinity DataEC50:  8.60E+3nMAssay Description:Inhibition of cPEPCK in rat H4IIE cells assessed as effect on glucose productionMore data for this Ligand-Target Pair
TargetPhosphoenolpyruvate carboxykinase, cytosolic [GTP](Rattus norvegicus (Rat))
The University Of Kansas Medical Center

LigandPNGBDBM50214004(CHEMBL243116 | N-(4-((1-(2-fluorobenzyl)-3-butyl-2...)
Affinity DataEC50:  3.97E+3nMAssay Description:Inhibition of cPEPCK in rat H4IIE cells assessed as effect on glucose productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphoenolpyruvate carboxykinase, cytosolic [GTP](Rattus norvegicus (Rat))
The University Of Kansas Medical Center

LigandPNGBDBM50214012(CHEMBL394368 | N-(4-((1-(2-fluorobenzyl)-3-(cyclop...)
Affinity DataEC50:  3.40E+3nMAssay Description:Inhibition of cPEPCK in rat H4IIE cells assessed as effect on glucose productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphoenolpyruvate carboxykinase, cytosolic [GTP](Rattus norvegicus (Rat))
The University Of Kansas Medical Center

LigandPNGBDBM50214013(CHEMBL242486 | N-(4-((1-(2-fluorobenzyl)-3-(cyclop...)
Affinity DataEC50:  5.50E+3nMAssay Description:Inhibition of cPEPCK in rat H4IIE cells assessed as effect on glucose productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphoenolpyruvate carboxykinase, cytosolic [GTP](Rattus norvegicus (Rat))
The University Of Kansas Medical Center

LigandPNGBDBM50214016(CHEMBL243342 | N-(4-((1-(2-fluorobenzyl)-3-(cyclop...)
Affinity DataEC50:  8.20E+3nMAssay Description:Inhibition of cPEPCK in rat H4IIE cells assessed as effect on glucose productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphoenolpyruvate carboxykinase, cytosolic [GTP](Rattus norvegicus (Rat))
The University Of Kansas Medical Center

LigandPNGBDBM50214010(CHEMBL244165 | N-(4-((1-(2-fluorobenzyl)-3-(cyclop...)
Affinity DataEC50:  4.70E+3nMAssay Description:Inhibition of cPEPCK in rat H4IIE cells assessed as effect on glucose productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphoenolpyruvate carboxykinase, cytosolic [GTP](Rattus norvegicus (Rat))
The University Of Kansas Medical Center

LigandPNGBDBM50214001(CHEMBL389494 | N-(4-((1-(2-fluorobenzyl)-3-(cyclop...)
Affinity DataEC50:  2.17E+3nMAssay Description:Inhibition of cPEPCK in rat H4IIE cells assessed as effect on glucose productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphoenolpyruvate carboxykinase, cytosolic [GTP](Rattus norvegicus (Rat))
The University Of Kansas Medical Center

LigandPNGBDBM50214003(CHEMBL243134 | N-(4-((1-(2-fluorobenzyl)-3-(cyclop...)
Affinity DataEC50:  8.75E+3nMAssay Description:Inhibition of cPEPCK in rat H4IIE cells assessed as effect on glucose productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphoenolpyruvate carboxykinase, cytosolic [GTP](Rattus norvegicus (Rat))
The University Of Kansas Medical Center

LigandPNGBDBM50214007(CHEMBL394621 | N-(4-((1-(2-fluorobenzyl)-3-(cyclop...)
Affinity DataEC50:  5.57E+3nMAssay Description:Inhibition of cPEPCK in rat H4IIE cells assessed as effect on glucose productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed