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388 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Synthesis 4-[2-(2-mercapto-4-oxo-4H-quinazolin-3-yl)-ethyl]-benzenesulfonamides with subnanomolar carbonic anhydrase II and XII inhibitory properties.EBI
Universit£
Bortezomib inhibits bacterial and fungalß-carbonic anhydrases.EBI
Universit£
PEGylated Bis-Sulfonamide Carbonic Anhydrase Inhibitors Can Efficiently Control the Growth of Several Carbonic Anhydrase IX-Expressing Carcinomas.EBI
Temple University School Of Pharmacy
An Unusual Natural Product Primary Sulfonamide: Synthesis, Carbonic Anhydrase Inhibition, and Protein X-ray Structures of Psammaplin C.EBI
Griffith University
Kinetic and X-ray crystallographic investigations of substituted 2-thio-6-oxo-1,6-dihydropyrimidine-benzenesulfonamides acting as carbonic anhydrase inhibitors.EBI
Universit£
Microwave assisted synthesis of novel acridine-acetazolamide conjugates and investigation of their inhibition effects on human carbonic anhydrase isoforms hCA I, II, IV and VII.EBI
Dumlupinar University
Synthesis of 4-(thiazol-2-ylamino)-benzenesulfonamides with carbonic anhydrase I, II and IX inhibitory activity and cytotoxic effects against breast cancer cell lines.EBI
Cairo University
Pyrazolylbenzo[d]imidazoles as new potent and selective inhibitors of carbonic anhydrase isoforms hCA IX and XII.EBI
Kurukshetra University
Novel sulfonamide bearing coumarin scaffolds as selective inhibitors of tumor associated carbonic anhydrase isoforms IX and XII.EBI
Kurukshetra University
Kinetically Selective Inhibitors of Human Carbonic Anhydrase Isozymes I, II, VII, IX, XII, and XIII.EBI
Uppsala University
Acetylcholinesterase and carbonic anhydrase inhibitory properties of novel urea and sulfamide derivatives incorporating dopaminergic 2-aminotetralin scaffolds.EBI
Erzurum Technical University
Comparison of the sulfonamide inhibition profiles of thea-,ß- and¿-carbonic anhydrases from the pathogenic bacterium Vibrio cholerae.EBI
Universit£
Isatin analogs as novel inhibitors of Candida spp.ß-carbonic anhydrase enzymes.EBI
Bezmialem Vakif University
Sulfonamide inhibition studies of theß-carbonic anhydrase from the newly discovered bacterium Enterobacter sp. B13.EBI
Recep Tayyip Erdogan University
Development of 3-(4-aminosulphonyl)-phenyl-2-mercapto-3H-quinazolin-4-ones as inhibitors of carbonic anhydrase isoforms involved in tumorigenesis and glaucoma.EBI
Dais
Anion inhibition studies of theß-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae.EBI
Universit£
Amido/ureidosubstituted benzenesulfonamides-isatin conjugates as low nanomolar/subnanomolar inhibitors of the tumor-associated carbonic anhydrase isoform XII.EBI
Egyptian Russian University
Sulfonamide inhibition studies of the¿-carbonic anhydrase from the Antarctic bacterium Colwellia psychrerythraea.EBI
Universit£
4-Arylbenzenesulfonamides as Human Carbonic Anhydrase Inhibitors (hCAIs): Synthesis by Pd Nanocatalyst-Mediated Suzuki-Miyaura Reaction, Enzyme Inhibition, and X-ray Crystallographic Studies.EBI
Universit£
Sulfonamide inhibition studies of theß-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae.EBI
Universit£
Kinetic and X-ray crystallographic investigations on carbonic anhydrase isoforms I, II, IX and XII of a thioureido analog of SLC-0111.EBI
University Of Florida College Of Medicine
A novel library of saccharin and acesulfame derivatives as potent and selective inhibitors of carbonic anhydrase IX and XII isoforms.EBI
University Of Chieti-Pescara
Pyridazinone substituted benzenesulfonamides as potent carbonic anhydrase inhibitors.EBI
Jamia Hamdard (Hamdard University)
Thioxocoumarins Show an Alternative Carbonic Anhydrase Inhibition Mechanism Compared to Coumarins.EBI
Universit£
Synthesis of 4-sulfamoylphenyl-benzylamine derivatives with inhibitory activity against human carbonic anhydrase isoforms I, II, IX and XII.EBI
Harran University
Optimization of allosteric MEK inhibitors. Part 2: Taming the sulfamide group balances compound distribution properties.EBI
Bayer Healthcare
Sulfonamide inhibition studies of thea-carbonic anhydrase from the gammaproteobacterium Thiomicrospira crunogena XCL-2, TcruCA.EBI
Universit£
Interaction of carbonic anhydrase isozymes I, II, and IX with some pyridine and phenol hydrazinecarbothioamide derivatives.EBI
Balikesir University
Discovery of 1,1'-Biphenyl-4-sulfonamides as a New Class of Potent and Selective Carbonic Anhydrase XIV Inhibitors.EBI
Sapienza University Of Rome
Inhibition of mammalian carbonic anhydrase isoforms I-XIV with a series of phenolic acid esters.EBI
Universit£
Isatin-pyrazole benzenesulfonamide hybrids potently inhibit tumor-associated carbonic anhydrase isoforms IX and XII.EBI
Egyptian Russian University
Carbonic anhydrase inhibitors: Design, synthesis, kinetic, docking and molecular dynamics analysis of novel glycine and phenylalanine sulfonamide derivatives.EBI
Gebze Technical University
New natural product carbonic anhydrase inhibitors incorporating phenol moieties.EBI
Aristotle University Of Thessaloniki
Click-tailed coumarins with potent and selective inhibitory action against the tumor-associated carbonic anhydrases IX and XII.EBI
Universit£
Synthesis of novel acridine bis-sulfonamides with effective inhibitory activity against the carbonic anhydrase isoforms I, II, IX and XII.EBI
Dumlupinar University
Activity and anion inhibition studies of thea-carbonic anhydrase from Thiomicrospira crunogena XCL-2 Gammaproteobacterium.EBI
University Of Florida
Phosphate Chemical Probes Designed for Location Specific Inhibition of Intracellular Carbonic Anhydrases.EBI
Griffith University
Cyclodextrin complexation highly enhances efficacy of arylsulfonylureido benzenesulfonamide carbonic anhydrase inhibitors as a topical antiglaucoma agents.EBI
Universit£
Carbonic anhydrase inhibitors: Design, synthesis and structural characterization of new heteroaryl-N-carbonylbenzenesulfonamides targeting druggable human carbonic anhydrase isoforms.EBI
Universit£
Synthesis of sulfonamides incorporating piperazinyl-ureido moieties and their carbonic anhydrase I, II, IX and XII inhibitory activity.EBI
University Of Cagliari
Exploring new Probenecid-based carbonic anhydrase inhibitors: Synthesis, biological evaluation and docking studies.EBI
University Of Chieti-Pescara
Probing the 'bipolar' nature of the carbonic anhydrase active site: aromatic sulfonamides containing 1,3-oxazol-5-yl moiety as picomolar inhibitors of cytosolic CA I and CA II isoforms.EBI
Saint Petersburg State University
Carbonic Anhydrase Glycoinhibitors belonging to the Aminoxysulfonamide Series.EBI
Institute Of Biomolecules Max Mousseron (Ibmm)
Sulfonamide inhibition studies of the¿-carbonic anhydrase from the Antarctic bacterium Pseudoalteromonas haloplanktis.EBI
Universit£
Synthesis and carbonic anhydrase I, II, IX and XII inhibitory activity of sulfamates incorporating piperazinyl-ureido moieties.EBI
University Of Cagliari
Mapping Selective Inhibition of the Cancer-Related Carbonic Anhydrase IX Using Structure-Activity Relationships of Glucosyl-Based Sulfamates.EBI
University Of Florida
Sulfonamide bearing pyrazolylpyrazolines as potent inhibitors of carbonic anhydrase isoforms I, II, IX and XII.EBI
Kurukshetra University
New 4-[(3-cyclohexyl-4-aryl-2,3-dihydro-1,3-thiazol-2-ylidene)amino]benzene-1-sulfonamides, synthesis and inhibitory activity toward carbonic anhydrase I, II, IX, XII.EBI
University Of Cagliari
Synthesis and carbonic anhydrase inhibitory properties of novel uracil derivatives.EBI
Agriibrahim£E£En University
Structure and inhibition studies of a type II beta-carbonic anhydrase psCA3 from Pseudomonas aeruginosa.EBI
University Of Florida
Anion inhibition study of theß-class carbonic anhydrase (PgiCAb) from the oral pathogen Porphyromonas gingivalis.EBI
Universit£
Discovery of a new family of carbonic anhydrases in the malaria pathogen Plasmodium falciparum--the¿-carbonic anhydrases.EBI
Istituto Di Bioscienze E Biorisorse (Ibbr)-Cnr
Cloning, characterization and anion inhibition studies of a new¿-carbonic anhydrase from the Antarctic bacterium Pseudoalteromonas haloplanktis.EBI
Istituto Di Bioscienze E Biorisorse
Design and synthesis of benzothiazole-6-sulfonamides acting as highly potent inhibitors of carbonic anhydrase isoforms I, II, IX and XII.EBI
Jazan University
5-Aryl-1H-pyrazole-3-carboxylic acids as selective inhibitors of human carbonic anhydrases IX and XII.EBI
University Of Belgrade
Discovery of potent carbonic anhydrase and acetylcholine esterase inhibitors: novel sulfamoylcarbamates and sulfamides derived from acetophenones.EBI
Agriibrahim£E£En University
New pyrazolo[4,3-e][1,2,4]triazine sulfonamides as carbonic anhydrase inhibitors.EBI
Siedlce University Of Natural Sciences And Humanities
New amide derivatives of Probenecid as selective inhibitors of carbonic anhydrase IX and XII: biological evaluation and molecular modelling studies.EBI
University Of Chieti-Pescara
6-Substituted sulfocoumarins are selective carbonic anhdydrase IX and XII inhibitors with significant cytotoxicity against colorectal cancer cells.EBI
Latvian Institute Of Organic Synthesis
Synthesis of Schiff base derivatives of 4-(2-aminoethyl)-benzenesulfonamide with inhibitory activity against carbonic anhydrase isoforms I, II, IX and XII.EBI
Harran University
Synthesis, carbonic anhydrase inhibition and cytotoxic activity of novel chromone-based sulfonamide derivatives.EBI
Cairo University
Carbonic anhydrase inhibitors with dual-tail moieties to match the hydrophobic and hydrophilic halves of the carbonic anhydrase active site.EBI
Griffith University
1,3,4-Thiadiazoles: a potent multi targeted pharmacological scaffold.EBI
University Of Mississippi
Theß-carbonic anhydrase from the malaria mosquito Anopheles gambiae is highly inhibited by sulfonamides.EBI
University Of Tampere And Tampere University Hospital
N-Acylsulfonamides strongly inhibit human carbonic anhydrase isoenzymes I and II.EBI
Atat£Rk University
Synthesis of a new series of dithiocarbamates with effective human carbonic anhydrase inhibitory activity and antiglaucoma action.EBI
Universit£
Sulfonamide inhibition studies of the¿-carbonic anhydrase from the Antarctic cyanobacterium Nostoc commune.EBI
Universit£
A class of sulfonamide carbonic anhydrase inhibitors with neuropathic pain modulating effects.EBI
Universit£
New approaches to the synthesis of sildenafil analogues and their enzyme inhibitory activity.EBI
Siedlce University Of Natural Sciences And Humanities
Synthesis of 6-aryl-substituted sulfocoumarins and investigation of their carbonic anhydrase inhibitory action.EBI
Latvian Institute Of Organic Synthesis
Sulfonamide inhibition studies of the¿-class carbonic anhydrase from the malaria pathogen Plasmodium falciparum.EBI
Universit£
Carbonic Anhydrase Inhibition with Benzenesulfonamides and Tetrafluorobenzenesulfonamides Obtained via Click Chemistry.EBI
Universit£
Sulfonamide inhibition study of the carbonic anhydrases from the bacterial pathogen Porphyromonas gingivalis: theß-class (PgiCAb) versus the¿-class (PgiCA) enzymes.EBI
Istituto Di Biochimica Delle Proteine-Cnr
Sulfonamides with Potent Inhibitory Action and Selectivity against thea-Carbonic Anhydrase from Vibrio cholerae.EBI
Universit£
Carbonic anhydrase inhibitors: design, synthesis, and biological evaluation of novel sulfonyl semicarbazide derivatives.EBI
Bharati Vidyapeeth'S College Of Pharmacy
Selective inhibition of human carbonic anhydrases by novel amide derivatives of probenecid: synthesis, biological evaluation and molecular modelling studies.EBI
Sapienza University Of Rome
Furazan and furoxan sulfonamides are stronga-carbonic anhydrase inhibitors and potential antiglaucoma agents.EBI
Universit£
Cyclic tertiary sulfamates: selective inhibition of the tumor-associated carbonic anhydrases IX and XII by N- and O-substituted acesulfame derivatives.EBI
Sapienza University Of Rome
Synthesis of sulfonamides with effective inhibitory action against Porphyromonas gingivalis¿-carbonic anhydrase.EBI
Universit£
Flow synthesis and biological activity of aryl sulfonamides as selective carbonic anhydrase IX and XII inhibitors.EBI
University Of Perugia
Inhibition studies of new ureido-substituted sulfonamides incorporating a GABA moiety against human carbonic anhydrase isoforms I-XIV.EBI
TBA
4-Functionalized 1,3-diarylpyrazoles bearing 6-aminosulfonylbenzothiazole moiety as potent inhibitors of carbonic anhydrase isoforms hCA I, II, IX and XII.EBI
Kurukshetra University
Carbonic anhydrase inhibitory activity of sulfonamides and carboxylic acids incorporating cyclic imide scaffolds.EBI
King Saud University
Ferrier sulfamidoglycosylation of glycals catalyzed by nitrosonium tetrafluoroborate: towards new carbonic anhydrase glycoinhibitors.EBI
Ecole Nationale Sup£Rieure De Chimie De Montpellier
Discovery and characterization of novel selective inhibitors of carbonic anhydrase IX.EBI
Vilnius University
A class of 4-sulfamoylphenyl-¿-aminoalkyl ethers with effective carbonic anhydrase inhibitory action and antiglaucoma effects.EBI
Universit£
Structural insights on carbonic anhydrase inhibitory action, isoform selectivity, and potency of sulfonamides and coumarins incorporating arylsulfonylureido groups.EBI
Universit£
Inhibition of carbonic anhydrase isoforms I, II, IX and XII with novel Schiff bases: identification of selective inhibitors for the tumor-associated isoforms over the cytosolic ones.EBI
Universit£
Novel sulfonamides bearing pyrrole and pyrrolopyrimidine moieties as carbonic anhydrase inhibitors: Synthesis, cytotoxic activity and molecular modeling.EBI
King Saud University
Structural insights into carbonic anhydrase IX isoform specificity of carbohydrate-based sulfamates.EBI
Griffith University
Substituted thieno[2,3-b]thiophenes and related congeners: Synthesis,ß-glucuronidase inhibition activity, crystal structure, and POM analyses.EBI
King Saud University
Quinazoline-sulfonamides with potent inhibitory activity against thea-carbonic anhydrase from Vibrio cholerae.EBI
Salman Bin Abdulaziz University
Attachment of carbohydrates to methoxyaryl moieties leads to highly selective inhibitors of the cancer associated carbonic anhydrase isoforms IX and XII.EBI
Universidad Nacional De La Plata
Carbonic anhydrase inhibitors: Synthesis, molecular docking, cytotoxic and inhibition of the human carbonic anhydrase isoforms I, II, IX, XII with novel benzenesulfonamides incorporating pyrrole, pyrrolopyrimidine and fused pyrrolopyrimidine moieties.EBI
King Saud University
Carbonic anhydrase inhibitors. Synthesis of a novel series of 5-substituted 2,4-dichlorobenzenesulfonamides and their inhibition of human cytosolic isozymes I and II and the transmembrane tumor-associated isozymes IX and XII.EBI
Medical University Of Gdansk
Oxidation of cyanobenzocycloheptatrienes: Synthesis, photooxygenation reaction and carbonic anhydrase isoenzymes inhibition properties of some new benzotropone derivatives.EBI
Agriibrahim£E£En University
Dual carbonic anhydrase/matrix metalloproteinase inhibitors incorporating bisphosphonic acid moieties targeting bone tumors.EBI
Universit£
Sulfonamide inhibition studies of twoß-carbonic anhydrases from the bacterial pathogen Legionella pneumophila.EBI
Kochi Medical School
Carbonic anhydrase inhibitors. Inhibition of human cytosolic isoforms I and II with (reduced) Schiff's bases incorporating sulfonamide, carboxylate and carboxymethyl moieties.EBI
Enscm/Umii/Umr-Cnrs 5635
Pyrazolo[4,3-e][1,2,4]triazine sulfonamides as carbonic anhydrase inhibitors with antitumor activity.EBI
Siedlce University Of Natural Sciences And Humanities
Synthesis and carbonic anhydrase I, II, IX and XII inhibition studies of 4-N,N-disubstituted sulfanilamides incorporating 4,4,4-trifluoro-3-oxo-but-1-enyl, phenacylthiourea and imidazol-2(3H)-one/thione moieties.EBI
University Of Cagliari
Cyclic secondary sulfonamides: unusually good inhibitors of cancer-related carbonic anhydrase enzymes.EBI
Griffith University
Arylamino bisphosphonates: potent and selective inhibitors of the tumor-associated carbonic anhydrase XII.EBI
Universit£
Discovery of new potent inhibitors for carbonic anhydrase IX by structure-based virtual screening.EBI
East China University Of Science And Technology
Xanthates and trithiocarbonates strongly inhibit carbonic anhydrases and show antiglaucoma effects in vivo.EBI
Universit£
The alpha-carbonic anhydrase from the thermophilic bacterium Sulfurihydrogenibium yellowstonense YO3AOP1 is highly susceptible to inhibition by sulfonamides.EBI
Universit£
Structural effect of phenyl ring compared to thiadiazole based adamantyl-sulfonamides on carbonic anhydrase inhibition.EBI
University Of Florida
Optimization of heterocyclic substituted benzenesulfonamides as novel carbonic anhydrase IX inhibitors and their structure activity relationship.EBI
East China University Of Science And Technology
Anion inhibition studies of thea-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae.EBI
Universit£
Kinetic and anion inhibition studies of aß-carbonic anhydrase (FbiCA 1) from the C4 plant Flaveria bidentis.EBI
Istituto Di Biostrutture E Bioimmagini
Novel sulfamides as potential carbonic anhydrase isoenzymes inhibitors.EBI
Atat£Rk University
4-Substituted-2,3,5,6-tetrafluorobenzenesulfonamides as inhibitors of carbonic anhydrases I, II, VII, XII, and XIII.EBI
Vilnius University Institute Of Biotechnology
o-Benzenedisulfonimido-sulfonamides are potent inhibitors of the tumor-associated carbonic anhydrase isoforms CA IX and CA XII.EBI
Istanbul University
Carbonic anhydrase inhibitors: benzenesulfonamides incorporating cyanoacrylamide moieties are low nanomolar/subnanomolar inhibitors of the tumor-associated isoforms IX and XII.EBI
Salman Bin Abdulaziz University
Inhibition pattern of sulfamide-related compounds in binding to carbonic anhydrase isoforms I, II, VII, XII and XIV.EBI
National University Of La Plata
QSAR studies of sulfamate and sulfamide inhibitors targeting human carbonic anhydrase isozymes I, II, IX and XII.EBI
Romanian Academy
Glycosidic carbonic anhydrase IX inhibitors: a sweet approach against cancer.EBI
Ecole Nationale Sup£Rieure De Chimie De Montpellier
New selective carbonic anhydrase IX inhibitors: synthesis and pharmacological evaluation of diarylpyrazole-benzenesulfonamides.EBI
University Of Lille
Synthesis of 1,4-bis(indolin-1-ylmethyl)benzene derivatives and their structure-activity relationships for the interaction of human carbonic anhydrase isoforms I and II.EBI
Karamanoglu Mehmetbey University
Salicylaldoxime derivatives as new leads for the development of carbonic anhydrase inhibitors.EBI
Universit£
Synthesis of C-cinnamoyl glycosides and their inhibitory activity against mammalian carbonic anhydrases.EBI
Universidad Nacional De La Plata
Purification and characterization of carbonic anhydrase from sheep kidney and effects of sulfonamides on enzyme activity.EBI
Agri Ibrahim Cecen University
Natural product coumarins that inhibit human carbonic anhydrases.EBI
Griffith University
Superacid synthesis of halogen containing N-substituted-4-aminobenzene sulfonamides: new selective tumor-associated carbonic anhydrase inhibitors.EBI
Superacide Et Chimie Des Syst£Mes£
Mono-/dihydroxybenzoic acid esters and phenol pyridinium derivatives as inhibitors of the mammalian carbonic anhydrase isoforms I, II, VII, IX, XII and XIV.EBI
Universit£
Cloning, characterization, and sulfonamide and thiol inhibition studies of ana-carbonic anhydrase from Trypanosoma cruzi, the causative agent of Chagas disease.EBI
University Of Tampere And Tampere University Hospital
Novel small molecule protein arginine deiminase 4 (PAD4) inhibitors.EBI
Universit£
Sulfocoumarins (1,2-benzoxathiine-2,2-dioxides): a class of potent and isoform-selective inhibitors of tumor-associated carbonic anhydrases.EBI
Latvian Association Of Human Genetics
Facile synthesis and characterization of novel pyrazole-sulfonamides and their inhibition effects on human carbonic anhydrase isoenzymes.EBI
Dumlupinar University
Restoring catalytic activity to the human carbonic anhydrase (CA) related proteins VIII, X and XI affords isoforms with high catalytic efficiency and susceptibility to anion inhibition.EBI
Kochi Medical School
Anion inhibition studies of the fastest carbonic anhydrase (CA) known, the extremo-CA from the bacterium Sulfurihydrogenibium azorense.EBI
Universit£
Carbonic anhydrase inhibitors. Regioselective synthesis of novel series 1-substituted 1,4-dihydro-4-oxo-3-pyridinesulfonamides and their inhibition of the human cytosolic isozymes I and II and transmembrane cancer-associated isozymes IX and XII.EBI
TBA
DNA cloning, characterization, and inhibition studies of ana-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae.EBI
Istituto Di Biochimica Delle Proteine-Cnr
Tricyclic sulfonamides incorporating benzothiopyrano[4,3-c]pyrazole and pyridothiopyrano[4,3-c]pyrazole effectively inhibita- andß-carbonic anhydrase: X-ray crystallography and solution investigations on 15 isoforms.EBI
Universit£
Carbamoylphosphonates control tumor cell proliferation and dissemination by simultaneously inhibiting carbonic anhydrase IX and matrix metalloproteinase-2. Toward nontoxic chemotherapy targeting tumor microenvironment.EBI
The Hebrew University Of Jerusalem
Development of potent carbonic anhydrase inhibitors incorporating both sulfonamide and sulfamide groups.EBI
Istituto Di Biostrutture E Bioimmagini-Cnr
Antimetastatic effect of sulfamate carbonic anhydrase IX inhibitors in breast carcinoma xenografts.EBI
University Of Manchester
Inhibition ofa-class cytosolic human carbonic anhydrases I, II, IX and XII, andß-class fungal enzymes by carboxylic acids and their derivatives: new isoform-I selective nanomolar inhibitors.EBI
Universit£
Ureido-substituted sulfamates show potent carbonic anhydrase IX inhibitory and antiproliferative activities against breast cancer cell lines.EBI
Ecole Nationale Sup£Rieure De Chimie De Montpellier
Synthesis, structure-activity relationship studies, and X-ray crystallographic analysis of arylsulfonamides as potent carbonic anhydrase inhibitors.EBI
Universit£
Molecular cloning, characterization, and inhibition studies of aß-carbonic anhydrase from Malassezia globosa, a potential antidandruff target.EBI
Union Life Sciences
Synthesis and carbonic anhydrase inhibitory properties of novel bromophenols and their derivatives including natural products: vidalol B.EBI
Atat£Rk University
Dithiocarbamates strongly inhibit carbonic anhydrases and show antiglaucoma action in vivo.EBI
Universit£
Flavones and structurally related 4-chromenones inhibit carbonic anhydrases by a different mechanism of action compared to coumarins.EBI
Universit£
Design of [(2-pyrimidinylthio)acetyl]benzenesulfonamides as inhibitors of human carbonic anhydrases.EBI
Vilnius University
Characterization and anions inhibition studies of ana-carbonic anhydrase from the teleost fish Dicentrarchus labrax.EBI
Ondokuz Mayis University
Pteridine-sulfonamide conjugates as dual inhibitors of carbonic anhydrases and dihydrofolate reductase with potential antitumor activity.EBI
Instituto Superior T£Cnico
Carbonic anhydrase inhibitors. Antioxidant polyphenols effectively inhibit mammalian isoforms I-XV.EBI
Universit£
Carbonic anhydrase inhibitors. The X-ray crystal structure of human isoform II in adduct with an adamantyl analogue of acetazolamide resides in a less utilized binding pocket than most hydrophobic inhibitors.EBI
University Of Florida
Coumarinyl-substituted sulfonamides strongly inhibit several human carbonic anhydrase isoforms: solution and crystallographic investigations.EBI
University Of Florida
New hydroxypyrimidinone-containing sulfonamides as carbonic anhydrase inhibitors also acting as MMP inhibitors.EBI
Lneg
Carbonic anhydrase inhibitors: crystallographic and solution binding studies for the interaction of a boron-containing aromatic sulfamide with mammalian isoforms I-XV.EBI
Istituto Di Biostrutture E Bioimmagini-Cnr
Sulfonamide linked neoglycoconjugates--a new class of inhibitors for cancer-associated carbonic anhydrases.EBI
Griffith University
Novel, broad-spectrum anticonvulsants containing a sulfamide group: advancement of N-((benzo[b]thien-3-yl)methyl)sulfamide (JNJ-26990990) into human clinical studies.EBI
Johnson & Johnson Pharmaceutical Research & Development
Synthesis, characterization and antiglaucoma activity of a novel proton transfer compound and a mixed-ligand Zn(II) complex.EBI
Dumlupinar University
Carbonic anhydrase inhibitors. Inhibition of mammalian isoforms I-XIV with a series of natural product polyphenols and phenolic acids.EBI
Universit£
Deciphering the mechanism of carbonic anhydrase inhibition with coumarins and thiocoumarins.EBI
Universita Degli Studi Di Firenze
Nitric oxide-donating carbonic anhydrase inhibitors for the treatment of open-angle glaucoma.EBI
Nicox Research Institute
The coumarin-binding site in carbonic anhydrase accommodates structurally diverse inhibitors: the antiepileptic lacosamide as an example and lead molecule for novel classes of carbonic anhydrase inhibitors.EBI
Universit£
Carbonic anhydrase inhibitors. Characterization and inhibition studies of the most active beta-carbonic anhydrase from Mycobacterium tuberculosis, Rv3588c.EBI
Universit£
S-glycosyl primary sulfonamides--a new structural class for selective inhibition of cancer-associated carbonic anhydrases.EBI
Griffith University
Carbonic anhydrase inhibitors. Inhibition studies of a coral secretory isoform by sulfonamides.EBI
Centre Scientifique De Monaco
Synthesis and evaluation of pharmacological profile of 1-aryl-6,7-dimethoxy-3,4-dihydroisoquinoline-2(1H)-sulfonamides.EBI
Universit£
Inhibition of carbonic anhydrase isozymes with benzene sulfonamides incorporating thio, sulfinyl and sulfonyl glycoside moieties.EBI
Griffith University
Carbonic anhydrase inhibitors. Inhibition of cytosolic isoforms I, II, III, VII and XIII with less investigated inorganic anions.EBI
Universit£
A thiabendazole sulfonamide shows potent inhibitory activity against mammalian and nematode alpha-carbonic anhydrases.EBI
Universit£
Carbonic anhydrase inhibitors: inhibition of the beta-class enzyme from the yeast Saccharomyces cerevisiae with sulfonamides and sulfamates.EBI
Balikesir University
Carbonic anhydrase inhibitors: 2-substituted-1,3,4-thiadiazole-5-sulfamides act as powerful and selective inhibitors of the mitochondrial isozymes VA and VB over the cytosolic and membrane-associated carbonic anhydrases I, II and IV.EBI
Ecole Nationale Sup£Rieure De Chimie De Montpellier
Inhibition of human mitochondrial carbonic anhydrases VA and VB with para-(4-phenyltriazole-1-yl)-benzenesulfonamide derivatives.EBI
Griffith University
Carbonic anhydrase inhibitors: design of spin-labeled sulfonamides incorporating TEMPO moieties as probes for cytosolic or transmembrane isozymes.EBI
Universit£
Carbonic anhydrase inhibitors: Inhibition of the new membrane-associated isoform XV with phenols.EBI
Universit£
Carbonic anhydrase inhibitors: the X-ray crystal structure of ethoxzolamide complexed to human isoform II reveals the importance of thr200 and gln92 for obtaining tight-binding inhibitors.EBI
Istituto Di Biostrutture E Bioimmagini-Cnr
Carbonic anhydrase inhibitors: copper(II) complexes of polyamino-polycarboxylamido aromatic/heterocyclic sulfonamides are very potent inhibitors of the tumor-associated isoforms IX and XII.EBI
Ecole Nationale Sup£Rieure De Chimie De Montpellier
Inhibition of carbonic anhydrases with glycosyltriazole benzene sulfonamides.EBI
Griffith University
Carbonic anhydrases as targets for medicinal chemistry.EBI
Universit£
Carbonic anhydrase inhibitors: cloning, characterization, and inhibition studies of the cytosolic isozyme III with sulfonamides.EBI
Kochi Medical School
Inhibition of carbonic anhydrase isozymes I, II and IX with benzenesulfonamides containing an organometallic moiety.EBI
Griffith University
Carbonic anhydrase inhibitors. Inhibition of isoforms I, II, IV, VA, VII, IX, and XIV with sulfonamides incorporating fructopyranose-thioureido tails.EBI
Ecole Nationale Sup£Rieure De Chimie De Montpellier
Phosph(on)ate as a zinc-binding group in metalloenzyme inhibitors: X-ray crystal structure of the antiviral drug foscarnet complexed to human carbonic anhydrase I.EBI
Universit£
Carbonic anhydrase and matrix metalloproteinase inhibitors. Inhibition of human tumor-associated isozymes IX and cytosolic isozyme I and II with sulfonylated hydroxamates.EBI
Universit£
Carbonic anhydrase inhibitors. DNA cloning, characterization, and inhibition studies of the human secretory isoform VI, a new target for sulfonamide and sulfamate inhibitors.EBI
Kochi Medical School
Carbonic anhydrase inhibitors: cloning and sulfonamide inhibition studies of a carboxyterminal truncated alpha-carbonic anhydrase from Helicobacter pylori.EBI
Kochi Medical School
Carbonic anhydrase inhibitors: Valdecoxib binds to a different active site region of the human isoform II as compared to the structurally related cyclooxygenase II"selective" inhibitor celecoxib.EBI
Istituto Di Biostrutture E Bioimmagini-Cnr
Carbonic anhydrase inhibitors: inhibition of the human isozymes I, II, VA, and IX with a library of substituted difluoromethanesulfonamides.EBI
Universit£
Designed multiple ligands. An emerging drug discovery paradigm.EBI
Organon Laboratories
Carbonic anhydrase inhibitors: the first on-resin screening of a 4-sulfamoylphenylthiourea library.EBI
University Of Florence
Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, IX, and XII with N-hydroxysulfamides--a new zinc-binding function in the design of inhibitors.EBI
Universit£
Carbonic anhydrase inhibitors. Inhibition of the human cytosolic isozyme VII with aromatic and heterocyclic sulfonamides.EBI
Universit£
Carbonic anhydrase inhibitors. Inhibition of the transmembrane isozyme XII with sulfonamides-a new target for the design of antitumor and antiglaucoma drugs?EBI
Universit£
Carbonic anhydrase inhibitors. Inhibition of the membrane-bound human and bovine isozymes IV with sulfonamides.EBI
Universit£
Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with bis-sulfamates.EBI
Universit£
Carbonic anhydrase inhibitors. Inhibition of isozymes I, II, IV, V, and IX with anions isosteric and isoelectronic with sulfate, nitrate, and carbonate.EBI
Universit£
Carbonic anhydrase inhibitors. Novel sulfanilamide/acetazolamide derivatives obtained by the tail approach and their interaction with the cytosolic isozymes I and II, and the tumor-associated isozyme IX.EBI
Harran University
Carbonic anhydrase inhibitors: inhibition of the transmembrane isozyme XIV with sulfonamides.EBI
Kochi Medical School
Carbonic anhydrase inhibitors: design of thioureido sulfonamides with potent isozyme II and XII inhibitory properties and intraocular pressure lowering activity in a rabbit model of glaucoma.EBI
Universita Degli Studi
Carbonic anhydrase inhibitors: novel sulfonamides incorporating 1,3,5-triazine moieties as inhibitors of the cytosolic and tumour-associated carbonic anhydrase isozymes I, II and IX.EBI
Universit£
Carbonic anhydrase inhibitors. Inhibition of the prokariotic beta and gamma-class enzymes from Archaea with sulfonamides.EBI
Pennsylvania State University
Carbonic anhydrase inhibitors. Design of anticonvulsant sulfonamides incorporating indane moieties.EBI
Universit£
Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides derived from 4-isothiocyanato-benzolamide.EBI
Universit£
Carbonic anhydrase inhibitors: inhibition of the membrane-bound human isozyme IV with anions.EBI
Universit£
Carbonic anhydrase inhibitors. Inhibition of the newly isolated murine isozyme XIII with anions.EBI
Universit£
Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides incorporating 1,2,4-triazine moieties.EBI
Universit£
Carbonic anhydrase inhibitors. Inhibition of the beta-class enzyme from the methanoarchaeon Methanobacterium thermoautotrophicum (Cab) with anions.EBI
Universit£
Carbonic anhydrase inhibitors: synthesis and topical intraocular pressure lowering effects of fluorine-containing inhibitors devoid of enhanced reactivity.EBI
Universit£
Carbonic anhydrase inhibitors. Inhibition of cytosolic isozymes I and II and transmembrane, tumor-associated isozyme IX with sulfamates including EMATE also acting as steroid sulfatase inhibitors.EBI
University Of Montpellier
Carbonic anhydrase inhibitors. A general approach for the preparation of water-soluble sulfonamides incorporating polyamino-polycarboxylate tails and of their metal complexes possessing long-lasting, topical intraocular pressure-lowering properties.EBI
Universit£
Carbonic anhydrase inhibitors: anticonvulsant sulfonamides incorporating valproyl and other lipophilic moieties.EBI
University Of Namur
Nonaromatic sulfonamide group as an ideal anchor for potent human carbonic anhydrase inhibitors: role of hydrogen-bonding networks in ligand binding and drug design.EBI
Universit£
Carbonic anhydrase inhibitors: water-soluble 4-sulfamoylphenylthioureas as topical intraocular pressure-lowering agents with long-lasting effects.EBI
Universit£
Carbonic anhydrase inhibitors: perfluoroalkyl/aryl-substituted derivatives of aromatic/heterocyclic sulfonamides as topical intraocular pressure-lowering agents with prolonged duration of action.EBI
Universit£
Carbonic anhydrase inhibitors: synthesis of water-soluble, aminoacyl/dipeptidyl sulfonamides possessing long-lasting intraocular pressure-lowering properties via the topical route.EBI
Universit£
Carbonic anhydrase inhibitors. Synthesis of water-soluble, topically effective, intraocular pressure-lowering aromatic/heterocyclic sulfonamides containing cationic or anionic moieties: is the tail more important than the ring?EBI
Universit£
Carbonic anhydrase inhibitors: the first selective, membrane-impermeant inhibitors targeting the tumor-associated isozyme IX.EBI
Slovak Academy Of Sciences
Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozyme IX with fluorine-containing sulfonamides. The first subnanomolar CA IX inhibitor discovered.EBI
Universit£
Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with the antipsychotic drug sulpiride.EBI
Bruker-Axs
Carbonic anhydrase inhibitors. Inhibition of cytosolic isozyme XIII with aromatic and heterocyclic sulfonamides: a novel target for the drug design.EBI
University Of Tampere
Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with EMATE, a dual inhibitor of carbonic anhydrases and steroid sulfatase.EBI
Universit£
Carbonic anhydrase inhibitors: N-(p-sulfamoylphenyl)-alpha-D-glycopyranosylamines as topically acting antiglaucoma agents in hypertensive rabbits.EBI
University Of Montpellier
Carbonic anhydrase inhibitors: E7070, a sulfonamide anticancer agent, potently inhibits cytosolic isozymes I and II, and transmembrane, tumor-associated isozyme IX.EBI
Universit£
Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozyme IX with aromatic and heterocyclic sulfonamides.EBI
Universit£
Carbonic anhydrase inhibitors: SAR and X-ray crystallographic study for the interaction of sugar sulfamates/sulfamides with isozymes I, II and IV.EBI
Universit£
Carbonic anhydrase inhibitors: inhibition of cytosolic isozymes I and II with sulfamide derivatives.EBI
Universit£
Carbonic anhydrase inhibitors: topically acting antiglaucoma sulfonamides incorporating esters and amides of 3- and 4-carboxybenzolamide.EBI
Universit£
Carbonic anhydrase inhibitors. Preparation of potent sulfonamides inhibitors incorporating bile acid tails.EBI
Universit£
Carbonic anhydrase inhibitors: synthesis of sulfonamides incorporating dtpa tails and of their zinc complexes with powerful topical antiglaucoma properties.EBI
Universit£
Carbonic anhydrase inhibitors: 4-sulfamoyl-benzenecarboxamides and 4-chloro-3-sulfamoyl-benzenecarboxamides with strong topical antiglaucoma properties.EBI
Universit£
Carbonic anhydrase inhibitors: topical sulfonamide antiglaucoma agents incorporating secondary amine moieties.EBI
Universit£
Carbonic anhydrase inhibitors: synthesis of N-morpholylthiocarbonylsulfenylamino aromatic/heterocyclic sulfonamides and their interaction with isozymes I, II and IV.EBI
Universit£
Novel coumarins and 2-thioxo-coumarins as inhibitors of the tumor-associated carbonic anhydrases IX and XII.EBI
Universit£
Design and synthesis of thiourea compounds that inhibit transmembrane anchored carbonic anhydrases.EBI
Griffith University
New chemotypes acting as isozyme-selective carbonic anhydrase inhibitors with low affinity for the offtarget cytosolic isoform II.EBI
Universit£
Anion inhibition studies of ana-carbonic anhydrase from the living fossil Astrosclera willeyana.EBI
Slovak Academy Of Sciences
Cloning, characterization and sulfonamide inhibition studies of ana-carbonic anhydrase from the living fossil sponge Astrosclera willeyana.EBI
Slovak Academy Of Sciences
Structure-activity relationships for the interaction of 5,10-dihydroindeno[1,2-b]indole derivatives with human and bovine carbonic anhydrase isoforms I, II, III, IV and VI.EBI
Ondokuz Mayis University
Synthesis and carbonic anhydrase inhibitory properties of novel cyclohexanonyl bromophenol derivatives.EBI
Artvin£Oruh University
Glycosyl coumarin carbonic anhydrase IX and XII inhibitors strongly attenuate the growth of primary breast tumors.EBI
Ecole Nationale Sup£Rieure De Chimie De Montpellier
5- and 6-membered (thio)lactones are prodrug type carbonic anhydrase inhibitors.EBI
Universit£
Synthesis and biological profile of new 1,2,3,4-tetrahydroisoquinolines as selective carbonic anhydrase inhibitors.EBI
Universit£
Phenylethynylbenzenesulfonamide regioisomers strongly and selectively inhibit the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII over the cytosolic isoforms I and II.EBI
University Of Alberta
Targeting hypoxic tumor cell viability with carbohydrate-based carbonic anhydrase IX and XII inhibitors.EBI
Griffith University
Synthesis of rhodamine B-benzenesulfonamide conjugates and their inhibitory activity against humana- and bacterial/fungalß-carbonic anhydrases.EBI
Ecole Nationale Sup£Rieure De Chimie De Montpellier
Carbonic anhydrase inhibitors. Synthesis, molecular structures, and inhibition of the human cytosolic isozymes I and II and transmembrane isozymes IX, XII (cancer-associated) and XIV with novel 3-pyridinesulfonamide derivatives.EBI
Medical University Of Gdansk
Inhibition studies of theß-carbonic anhydrases from the bacterial pathogen Salmonella enterica serovar Typhimurium with sulfonamides and sulfamates.EBI
Kochi Medical School
Sulfonamides incorporating 1,3,5-triazine moieties selectively and potently inhibit carbonic anhydrase transmembrane isoforms IX, XII and XIV over cytosolic isoforms I and II: Solution and X-ray crystallographic studies.EBI
Universit£
N-ß-glycosyl sulfamides are selective inhibitors of the cancer associated carbonic anhydrase isoforms IX and XII.EBI
Universidad Nacional De La Plata
In vitro inhibition ofa-carbonic anhydrase isozymes by some phenolic compounds.EBI
Gumushane University
Conformational variability of different sulfonamide inhibitors with thienyl-acetamido moieties attributes to differential binding in the active site of cytosolic human carbonic anhydrase isoforms.EBI
University Of Florida
Sulfonamides incorporating boroxazolidone moieties are potent inhibitors of the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII.EBI
Ecole Nationale Sup£Rieure De Chimie De Montpellier
Carbonic anhydrase inhibitors. Phenacetyl-, pyridylacetyl- and thienylacetyl-substituted aromatic sulfonamides act as potent and selective isoform VII inhibitors.EBI
Istanbul University
Anticonvulsant 4-aminobenzenesulfonamide derivatives with branched-alkylamide moieties: X-ray crystallography and inhibition studies of human carbonic anhydrase isoforms I, II, VII, and XIV.EBI
The Hebrew University Of Jerusalem
Inhibition studies with anions and small molecules of two novel β-carbonic anhydrases from the bacterial pathogen Salmonella enterica serovar Typhimurium.EBI
Universit£
Synthesis and crystallographic analysis of new sulfonamides incorporating NO-donating moieties with potent antiglaucoma action.EBI
U.O. Oculistica Az. Usl 3
Virtual screening-driven identification of human carbonic anhydrase inhibitors incorporating an original, new pharmacophore.EBI
Universit£
Carbonic anhydrase inhibitors. Inhibition of the β-class enzymes from the fungal pathogens Candida albicans and Cryptococcus neoformans with branched aliphatic/aromatic carboxylates and their derivatives.EBI
Universit£
Purification and inhibition studies with anions and sulfonamides of ana-carbonic anhydrase from the Antarctic seal Leptonychotes weddellii.EBI
Universit£
Ureido-substituted benzenesulfonamides potently inhibit carbonic anhydrase IX and show antimetastatic activity in a model of breast cancer metastasis.EBI
Universita` Degli Studi Di Firenze
Natural product-based phenols as novel probes for mycobacterial and fungal carbonic anhydrases.EBI
Griffith University
Design, synthesis, and biological evaluation of novel carbohydrate-based sulfamates as carbonic anhydrase inhibitors.EBI
Griffith University
(R)-/(S)-10-camphorsulfonyl-substituted aromatic/heterocyclic sulfonamides selectively inhibit mitochondrial over cytosolic carbonic anhydrases.EBI
Universit£
A newß-carbonic anhydrase from Brucella suis, its cloning, characterization, and inhibition with sulfonamides and sulfamates, leading to impaired pathogen growth.EBI
University Of Montpellier
Kinetic and docking studies of phenol-based inhibitors of carbonic anhydrase isoforms I, II, IX and XII evidence a new binding mode within the enzyme active site.EBI
University Of Calgary
Carbonic anhydrase inhibitors. Inhibition studies with anions and sulfonamides of a new cytosolic enzyme from the scleractinian coral Stylophora pistillata.EBI
Centre Scientifique De Monaco
Inhibition of theß-carbonic anhydrase from Streptococcus pneumoniae by inorganic anions and small molecules: Toward innovative drug design of antiinfectives?EBI
Radboud University Nijmegen Medical Centre
7,8-disubstituted- but not 6,7-disubstituted coumarins selectively inhibit the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII over the cytosolic ones I and II in the low nanomolar/subnanomolar range.EBI
Università
Synthesis, characterization and antiglaucoma activity of some novel pyrazole derivatives of 5-amino-1,3,4-thiadiazole-2-sulfonamide.EBI
Dumlupinar University
Indapamide-like benzenesulfonamides as inhibitors of carbonic anhydrases I, II, VII, and XIII.EBI
Institute Of Biotechnology
4-[N-(substituted 4-pyrimidinyl)amino]benzenesulfonamides as inhibitors of carbonic anhydrase isozymes I, II, VII, and XIII.EBI
Vilnius University
Design, solid-phase synthesis, and biological evaluation of novel 1,5-diarylpyrrole-3-carboxamides as carbonic anhydrase IX inhibitors.EBI
University Of Lille
Paraoxon, 4-nitrophenyl phosphate and acetate are substrates ofa- but not ofß-,¿- and¿-carbonic anhydrases.EBI
Università
Carbonic anhydrase inhibitors. Regioselective synthesis of novel 1-substituted 1,4-dihydro-4-oxo-3-pyridinesulfonamides and their inhibition of the human cytosolic isozymes I and II and transmembrane cancer-associated isozymes IX and XII.EBI
Medical University Of Gdansk
Mutation of Phe91 to Asn in human carbonic anhydrase I unexpectedly enhanced both catalytic activity and affinity for sulfonamide inhibitors.EBI
Balikesir University
Polyamines inhibit carbonic anhydrases by anchoring to the zinc-coordinated water molecule.EBI
Universita Degli Studi Di Firenze
Ligand-directed tosyl chemistry for protein labeling in vivo.EBI
Kyoto University
A novel and one-pot synthesis of new 1-tosyl pyrrol-2-one derivatives and analysis of carbonic anhydrase inhibitory potencies.EBI
Atat£Rk University
Carbonic anhydrase inhibitors: synthesis and inhibition of the human cytosolic isozymes I and II and transmembrane isozymes IX, XII (cancer-associated) and XIV with 4-substituted 3-pyridinesulfonamides.EBI
Medical University Of Gdansk
NO-releasing esters show carbonic anhydrase inhibitory action against human isoforms I and II.EBI
Atat£Rk University
Inhibition studies of a beta-carbonic anhydrase from Brucella suis with a series of water soluble glycosyl sulfanilamides.EBI
Universit£
The proteoglycan region of the tumor-associated carbonic anhydrase isoform IX acts as anintrinsic buffer optimizing CO2 hydration at acidic pH values characteristic of solid tumors.EBI
Universita Degli Studi Di Firenze
The protein tyrosine kinase inhibitors imatinib and nilotinib strongly inhibit several mammalian alpha-carbonic anhydrase isoforms.EBI
University Of Tampere And Tampere University Hospital
Carbonic anhydrase inhibitors. Inhibition of the fungal beta-carbonic anhydrases from Candida albicans and Cryptococcus neoformans with boronic acids.EBI
Universit£
Carbonic anhydrase-encoded dynamic constitutional libraries: toward the discovery of isozyme-specific inhibitors.EBI
Enscm/Umii/Umr-Cnrs 5635
Discovery of low nanomolar and subnanomolar inhibitors of the mycobacterial beta-carbonic anhydrases Rv1284 and Rv3273.EBI
Istanbul University
Effects of new 5-amino-1,3,4-thiadiazole-2-sulfonamide derivatives on human carbonic anhydrase isozymes.EBI
Dumlupinar University
Carbonic anhydrase inhibitors. Inhibition of human erythrocyte isozymes I and II with a series of antioxidant phenols.EBI
Ataturk University
Carbonic anhydrase inhibitors: inhibition studies of a coral secretory isoform with inorganic anions.EBI
Centre Scientifique De Monaco
Ligand-based and structure-based virtual screening to identify carbonic anhydrase IX inhibitors.EBI
University Of Namur
Dual inhibitors of matrix metalloproteinases and carbonic anhydrases: iminodiacetyl-based hydroxamate-benzenesulfonamide conjugates.EBI
Instituto Superior TéCnico
Carbonic anhydrase inhibitors. Inhibition of the beta-class enzyme from the yeast Saccharomyces cerevisiae with anions.EBI
Balikesir University
In vitro inhibition of salicylic acid derivatives on human cytosolic carbonic anhydrase isozymes I and II.EBI
Ataturk University
Recent developments of carbonic anhydrase inhibitors as potential anticancer drugs.EBI
University Of Namur
Investigations of the esterase, phosphatase, and sulfatase activities of the cytosolic mammalian carbonic anhydrase isoforms I, II, and XIII with 4-nitrophenyl esters as substrates.EBI
Universita Degli Studi Di Firenze
Design, synthesis, and docking studies of new 1,3,4-thiadiazole-2-thione derivatives with carbonic anhydrase inhibitory activity.EBI
Assiut University
Benzimidazo[1,2-c][1,2,3]thiadiazole-7-sulfonamides as inhibitors of carbonic anhydrase.EBI
Institute Of Biotechnology
Carbonic anhydrase inhibitors. Inhibition of transmembrane isozymes XII (cancer-associated) and XIV with anions.EBI
Università
Carbonic anhydrase inhibitors. Inhibition of the cytosolic human isozymes I and II, and the transmembrane, tumor-associated isozymes IX and XII with substituted aromatic sulfonamides activatable in hypoxic tumors.EBI
Medical University Of Gdansk
Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozymes IX and XII with a library of aromatic and heteroaromatic sulfonamides.EBI
Università
Carbonic anhydrase inhibitors: inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with benzo[b]thiophene 1,1-dioxide sulfonamides.EBI
Università
Carbonic anhydrase inhibitors. Design of fluorescent sulfonamides as probes of tumor-associated carbonic anhydrase IX that inhibit isozyme IX-mediated acidification of hypoxic tumors.EBI
Università
Carbonic anhydrase inhibitors. Inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, IX, and XII with Schiff's bases incorporating chromone and aromatic sulfonamide moieties, and their zinc complexes.EBI
Ospedale San Lazzaro
Carbonic anhydrase inhibitors. Synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with boron-containing sulfonamides, sulfamides, and sulfamates: toward agents for boron neutron capture therapy of hypoxic tumors.EBI
Università
Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides incorporating thioureido-sulfanilyl scaffolds.EBI
Ospedale San Lazzaro
Carbonic anhydrase inhibitors. Inhibition of the cytosolic and tumor-associated carbonic anhydrase isozymes I, II, and IX with a series of 1,3,4-thiadiazole- and 1,2,4-triazole-thiols.EBI
University Of Bucharest
Carbonic anhydrase inhibitors: X-ray crystal structure of a benzenesulfonamide strong CA II and CA IX inhibitor bearing a pentafluorophenylaminothioureido tail in complex with isozyme II.EBI
University Of Naples 'Federico Ii
Carbonic anhydrase inhibitors. Inhibition of isozymes I, II, IV, V and IX with complex fluorides, chlorides and cyanides.EBI
Università
Carbonic anhydrase inhibitors. Interaction of isozymes I, II, IV, V, and IX with carboxylates.EBI
Università
Carbonic anhydrase inhibitors. Interaction of isozymes I, II, IV, V, and IX with phosphates, carbamoyl phosphate, and the phosphonate antiviral drug foscarnet.EBI
Università
Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with a topically acting antiglaucoma sulfonamide.EBI
Bruker-Axs
Carbonic anhydrase inhibitors: inhibition of transmembrane, tumor-associated isozyme IX, and cytosolic isozymes I and II with aliphatic sulfamates.EBI
University Of Montpellier
Carbonic anhydrase inhibitors: synthesis of membrane-impermeant low molecular weight sulfonamides possessing in vivo selectivity for the membrane-bound versus cytosolic isozymes.EBI
Università
Sulfonylmethanesulfonamide inhibitors of carbonic anhydrase.EBI
Merck Research Laboratories
Acetaldehyde-derived modifications on cytosolic human carbonic anhydrases.BDB
University Of Tampere And Tampere University Hospital
A Rapid and Efficient Assay for the Characterization of Substrates and Inhibitors of Nicotinamide N-Methyltransferase.BDB
Utrecht University
Synthesis and tyrosinase inhibition activity of trans-stilbene derivatives.BDB
Indian Institute Of Integrative Medicine
Identification of a novel human eicosanoid receptor coupled to G(i/o).BDB
Tanabe Seiyaku
Pharmacological actions of a novel, high-affinity, and selective human dopamine D(3) receptor antagonist, SB-277011-A.BDB
Smithkline Beecham Pharmaceuticals
Agonist-directed trafficking of porcine alpha(2A)-adrenergic receptor signaling in Chinese hamster ovary cells: l-isoproterenol selectively activates G(s).BDB
University Of Michigan
SR 142801, the first potent non-peptide antagonist of the tachykinin NK3 receptor.BDB
Sanofi Recherche
Cloning and pharmacological characterization of human alpha-1 adrenergic receptors: sequence corrections and direct comparison with other species homologues.BDB
Duke University
The 5-HT4 receptor: molecular cloning and pharmacological characterization of two splice variants.BDB
Synaptic Pharmaceutical
7-[3-(4-[2,3-Dimethylphenyl]piperazinyl)propoxy]-2(1H)-quinolinone (OPC-4392), a presynaptic dopamine autoreceptor agonist and postsynaptic D2 receptor antagonist.BDB
Tokushima Research Institute
Detection of a novel serotonin receptor subtype (5-HT1E) in human brain: interaction with a GTP-binding protein.BDB
Albany Medical College
Characterization of the striatal M2 muscarinic receptor mediating inhibition of cyclic AMP using selective antagonists: a comparison with the brainstem M2 receptor.BDB
Abbott Laboratories
Pharmacological characterization of the M1 muscarinic receptors expressed in murine fibroblast B82 cells.BDB
University Of Arizona
Design, synthesis, and SAR of cis-1,2-diaminocyclohexane derivatives as potent factor Xa inhibitors. Part I: exploration of 5-6 fused rings as alternative S1 moieties.BDB
Daiichi Sankyo
Optimization of (4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzazepine-5-ylidene)acetamide derivatives as arginine vasopressin V2 receptor agonists and discussion of their binding modes.BDB
Astellas Pharma
Selective inhibitors of the mutant B-Raf pathway: discovery of a potent and orally bioavailable aminoisoquinoline.BDB
Amgen
A fluorescence quenching assay to discriminate between specific and nonspecific inhibitors of dengue virus protease.BDB
Novartis Institute For Tropical Diseases
2-Cyclohexylcarbonylbenzimidazoles as potent, orally available and brain-penetrable opioid receptor-like 1 (ORL1) antagonists.BDB
Banyu Pharmaceutical
Novel tricyclic inhibitors of IkappaB kinase.BDB
Bristol-Myers Squibb
Design of annulated pyrazoles as inhibitors of HIV-1 reverse transcriptase.BDB
Roche Palo Alto
Novel Indazole Non-Nucleoside Reverse Transcriptase Inhibitors Using Molecular Hybridization Based on Crystallographic Overlays (dagger).BDB
Pfizer
Novel inhibitors of fatty acid amide hydrolase.BDB
Bristol-Myers Squibb