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25 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Pyrrolidinobenzoic acid inhibitors of influenza virus neuraminidase: the hydrophobic side chain influences type A subtype selectivity.EBI
University Of Alabama At Birmingham
Limited inhibitory effects of oseltamivir and zanamivir on human sialidases.EBI
Miyagi Cancer Center Research Institute
Fragment-based drug discovery.EBI
Sunesis Pharmaceuticals
BCX-1812 (RWJ-270201): discovery of a novel, highly potent, orally active, and selective influenza neuraminidase inhibitor through structure-based drug design.EBI
Biocryst Pharmaceuticals
Binding constants of neuraminidase inhibitors: An investigation of the linear interaction energy method.EBI
University Of Southampton
Dihydropyrancarboxamides related to zanamivir: a new series of inhibitors of influenza virus sialidases. 2. Crystallographic and molecular modeling study of complexes of 4-amino-4H-pyran-6-carboxamides and sialidase from influenza virus types A and B.EBI
Glaxo Wellcome Research And Development
Molecular modeling studies on ligand binding to sialidase from influenza virus and the mechanism of catalysis.EBI
Monash University
Sialidase inhibitors related to zanamivir. Further SAR studies of 4-amino-4H-pyran-2-carboxylic acid-6-propylamides.EBI
Glaxowellcome Medicines Research Centre
 
Novel inhibitors of influenza sialidases related to zanamivir. Heterocyclic replacements of the glycerol sidechainEBI
TBA
 
Novel inhibitors of influenza sialidases related to GG167 structure-activity, crystallographic and Molecular dynamics studies with 4H-pyran-2-carboxylic acid 6-carboxamidesEBI
TBA
 
Novel inhibitors of influenza sialidase related to GG167 Synthesis of 4-amino and guanidino-4H-pyran-2-carboxylic acid-6-propylamides; selective inhibitors of influenza a virus sialidaseEBI
TBA
Synthesis and biological evaluation of sialic acid derivatives containing a long hydrophobic chain at the anomeric position and their C-5 linked polymers as potent influenza virus inhibitors.EBI
Saitama University
3D QSAR and docking study of flavone derivatives as potent inhibitors of influenza H1N1 virus neuraminidase.EBI
Chinese Academy Of Medical Sciences
Antiviral potential and molecular insight into neuraminidase inhibiting diarylheptanoids from Alpinia katsumadai.EBI
University Of Innsbruck
Dimeric zanamivir conjugates with various linking groups are potent, long-lasting inhibitors of influenza neuraminidase including H5N1 avian influenza.EBI
Glaxosmithkline
Design, synthesis, and structural analysis of inhibitors of influenza neuraminidase containing a 2,3-disubstituted tetrahydrofuran-5-carboxylic acid core.EBI
Abbott Laboratories
Design, synthesis, and structural analysis of influenza neuraminidase inhibitors containing pyrrolidine cores.EBI
Abbott Laboratories
Potent inhibition of influenza sialidase by a benzoic acid containing a 2-pyrrolidinone substituent.EBI
University Of Alabama At Birmingham
Novel 5-azaindole factor VIIa inhibitors.BDB
Celera
Structure-activity relationships of the p38alpha MAP kinase inhibitor 1-(5-tert-butyl-2-p-tolyl-2H-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)naph- thalen-1-yl]urea (BIRB 796).BDB
Boehringer Ingelheim Pharmaceuticals
Inhibition of p38 MAP kinase by utilizing a novel allosteric binding site.BDB
Boehringer Ingelheim Pharmaceuticals
1-(5-Chloro-2-alkoxyphenyl)-3-(5-cyanopyrazin-2-yl)ureas [correction of cyanopyrazi] as potent and selective inhibitors of Chk1 kinase: synthesis, preliminary SAR, and biological activities.BDB
Abbott Laboratories
Bicyclic and tricyclic thiophenes as protein tyrosine phosphatase 1B inhibitors.BDB
Wyeth Research
Thermodynamics of substrate binding to the chaperone SecB.BDB
Indian Institute Of Science