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19 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Pyrrolidinobenzoic acid inhibitors of influenza virus neuraminidase: the hydrophobic side chain influences type A subtype selectivity.EBI
University Of Alabama At Birmingham
Synthesis of potent pyrrolidine influenza neuraminidase inhibitors.EBI
Abbott Laboratories
BCX-1812 (RWJ-270201): discovery of a novel, highly potent, orally active, and selective influenza neuraminidase inhibitor through structure-based drug design.EBI
Biocryst Pharmaceuticals
Dihydropyrancarboxamides related to zanamivir: a new series of inhibitors of influenza virus sialidases. 2. Crystallographic and molecular modeling study of complexes of 4-amino-4H-pyran-6-carboxamides and sialidase from influenza virus types A and B.EBI
Glaxo Wellcome Research And Development
Sialidase inhibitors related to zanamivir. Further SAR studies of 4-amino-4H-pyran-2-carboxylic acid-6-propylamides.EBI
Glaxowellcome Medicines Research Centre
 
Novel inhibitors of influenza sialidases related to zanamivir. Heterocyclic replacements of the glycerol sidechainEBI
TBA
 
Novel inhibitors of influenza sialidases related to GG167 structure-activity, crystallographic and Molecular dynamics studies with 4H-pyran-2-carboxylic acid 6-carboxamidesEBI
TBA
 
Novel inhibitors of influenza sialidase related to GG167 Synthesis of 4-amino and guanidino-4H-pyran-2-carboxylic acid-6-propylamides; selective inhibitors of influenza a virus sialidaseEBI
TBA
Design, synthesis, and structural analysis of inhibitors of influenza neuraminidase containing a 2,3-disubstituted tetrahydrofuran-5-carboxylic acid core.EBI
Abbott Laboratories
Design, synthesis, and structural analysis of influenza neuraminidase inhibitors containing pyrrolidine cores.EBI
Abbott Laboratories
Potent inhibition of influenza sialidase by a benzoic acid containing a 2-pyrrolidinone substituent.EBI
University Of Alabama At Birmingham
Evolution of a highly selective and potent 2-(pyridin-2-yl)-1,3,5-triazine Tie-2 kinase inhibitor.BDB
Amgen
Alkynylpyrimidine amide derivatives as potent, selective, and orally active inhibitors of Tie-2 kinase.BDB
Amgen
Novel 5-azaindole factor VIIa inhibitors.BDB
Celera
Structure-activity relationships of the p38alpha MAP kinase inhibitor 1-(5-tert-butyl-2-p-tolyl-2H-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)naph- thalen-1-yl]urea (BIRB 796).BDB
Boehringer Ingelheim Pharmaceuticals
Inhibition of p38 MAP kinase by utilizing a novel allosteric binding site.BDB
Boehringer Ingelheim Pharmaceuticals
Bicyclic and tricyclic thiophenes as protein tyrosine phosphatase 1B inhibitors.BDB
Wyeth Research
The structural basis for the selectivity of benzotriazole inhibitors of PTP1B.BDB
Merck Research Laboratories
Thermodynamics of substrate binding to the chaperone SecB.BDB
Indian Institute Of Science