PMID

Data

Article Title

Organization

Amino acid conjugates of lithocholic acid as antagonists of the EphA2 receptor.

Universit£

A quantitative analysis of kinase inhibitor selectivity.

Ambit Biosciences

7,8-dichloro-1-oxo-ß-carbolines as a versatile scaffold for the development of potent and selective kinase inhibitors with unusual binding modes.

Ludwig-Maximilians University Of Munich

Fragment based lead discovery of small molecule inhibitors for the EPHA4 receptor tyrosine kinase.

Vu University Amsterdam

Discovery of a novel class of non-ATP site DFG-out state p38 inhibitors utilizing computationally assisted virtual fragment-based drug design (vFBDD).

Ansaris

Comprehensive analysis of kinase inhibitor selectivity.

Ambit Biosciences

Discovery of 3-(2,6-dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea (NVP-BGJ398), a potent and selective inhibitor of the fibroblast growth factor receptor family of receptor tyrosine kinase.

Novartis Institute For Biomedical Research

Kinase Inhibition by Deoxy Analogues of the Resorcylic Lactone L-783277

TBA

AC220 is a uniquely potent and selective inhibitor of FLT3 for the treatment of acute myeloid leukemia (AML).

Ambit Biosciences

Structure-based optimization of potent and selective inhibitors of the tyrosine kinase erythropoietin producing human hepatocellular carcinoma receptor B4 (EphB4).

University Of Zurich

Assessment of chemical coverage of kinome space and its implications for kinase drug discovery.

Glaxosmithkline

A small molecule-kinase interaction map for clinical kinase inhibitors.

Ambit Biosciences

Amisulpride is a potent 5-HT7 antagonist: relevance for antidepressant actions in vivo.

Case Western Reserve University