41 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Hernandezine, a Bisbenzylisoquinoline Alkaloid with Selective Inhibitory Activity against Multidrug-Resistance-Linked ATP-Binding Cassette Drug Transporter ABCB1.
Chang Gung Memorial Hospital
Pyrrolopyrimidine Derivatives as Novel Inhibitors of Multidrug Resistance-Associated Protein 1 (MRP1, ABCC1).
University Of Bonn
Flavonoid derivatives as selective ABCC1 modulators: Synthesis and functional characterization.
University Of Regensburg
Potent and Nontoxic Chemosensitizer of P-Glycoprotein-Mediated Multidrug Resistance in Cancer: Synthesis and Evaluation of Methylated Epigallocatechin, Gallocatechin, and Dihydromyricetin Derivatives.
The Hong Kong Polytechnic University
Cannabinoid type 1 receptor antagonists modulate transport activity of multidrug resistance-associated proteins MRP1, MRP2, MRP3, and MRP4.
Radboud University Nijmegen Medical Centre
Trimethoxybenzanilide-based P-glycoprotein modulators: an interesting case of lipophilicity tuning by intramolecular hydrogen bonding.
Universit£
SAR studies on tetrahydroisoquinoline derivatives: the role of flexibility and bioisosterism to raise potency and selectivity toward P-glycoprotein.
Universit£
Thieno[2,3-b]pyridines--a new class of multidrug resistance (MDR) modulators.
Institute Of Organic Synthesis
Investigation of quinazolines as inhibitors of breast cancer resistance protein (ABCG2).
University Of Bonn
Synthesis and biological evaluation of flavones and benzoflavones as inhibitors of BCRP/ABCG2.
University Of Bonn
Activity-lipophilicity relationship studies on P-gp ligands designed as simplified tariquidar bulky fragments.
Universit£
Potent and selective tariquidar bioisosters as potential PET radiotracers for imaging P-gp.
Universit£
Anthracyclines modulate multidrug resistance protein (MRP) mediated organic anion transport.
Academic Hospital Vrije Universiteit
Transport of glutathione, glucuronate, and sulfate conjugates by the MRP gene-encoded conjugate export pump.
Deutsches Krebsforschungszentrum
ATP-dependent transport of bilirubin glucuronides by the multidrug resistance protein MRP1 and its hepatocyte canalicular isoform MRP2.
Deutsches Krebsforschungszentrum
Modulation of multidrug resistance protein 1 (MRP1/ABCC1) transport and atpase activities by interaction with dietary flavonoids.
Queen'S University
ATP-dependent 17 beta-estradiol 17-(beta-D-glucuronide) transport by multidrug resistance protein (MRP). Inhibition by cholestatic steroids.
Queen'S University
Multidrug resistance protein 1 (MRP1, ABCC1) mediates resistance to mitoxantrone via glutathione-dependent drug efflux.
Wake Forest University School Of Medicine
Interaction of ivermectin with multidrug resistance proteins (MRP1, 2 and 3).
Laboratoire De Pharmacologie-Toxicologie Inra
Reversal of resistance in multidrug resistance protein (MRP1)-overexpressing cells by LY329146.
Eli Lilly
Discovery of GS-9451: an acid inhibitor of the hepatitis C virus NS3/4A protease.
Gilead Sciences
Substituted chromones as highly potent nontoxic inhibitors, specific for the breast cancer resistance protein.
Cnrs/Universit£
A 4-aminobenzoic acid derivative as novel lead for selective inhibitors of multidrug resistance-associated proteins.
University Of Bonn
Potent galloyl-based selective modulators targeting multidrug resistance associated protein 1 and P-glycoprotein.
Universit£
Molecular docking studies and in vitro screening of new dihydropyridine derivatives as human MRP1 inhibitors.
Kakatiya University
Interaction potential of etravirine with drug transporters assessed in vitro.
University Hospital Heidelberg
Structure-activity relationships of flavonoids as inhibitors of breast cancer resistance protein (BCRP).
University Of Bonn
Phenylsulfonylfuroxans as modulators of multidrug-resistance-associated protein-1 and P-glycoprotein.
Universita Degli Studi Di Torino
Novel lead for potent inhibitors of breast cancer resistance protein (BCRP).
University Of Bonn
Modulation of multidrug resistance protein 1 (MRP1/ABCC1)-mediated multidrug resistance by bivalent apigenin homodimers and their derivatives.
The Hong Kong Polytechnic University
Aromatic 2-(thio)ureidocarboxylic acids as a new family of modulators of multidrug resistance-associated protein 1: synthesis, biological evaluation, and structure-activity relationships.
University Of Bonn
(R)- and (S)-verapamil differentially modulate the multidrug-resistant protein MRP1.
Institut De Biologie Et Chimie Des ProtéInes
Cyclohexyl-linked tricyclic isoxazoles are potent and selective modulators of the multidrug resistance protein (MRP1).
Eli Lilly
Topological model for the prediction of MRP1 inhibitory activity of pyrrolopyrimidines and templates derived from pyrrolopyrimidine.
M.D. University
Design and synthesis of new templates derived from pyrrolopyrimidine as selective multidrug-resistance-associated protein inhibitors in multidrug resistance.
Xenova
Studies on pyrrolopyrimidines as selective inhibitors of multidrug-resistance-associated protein in multidrug resistance.
Xenova