PMID

Data

Article Title

Organization

2-(Thienothiazolylimino)-1,3-thiazolidin-4-ones inhibit cell division cycle 25 A phosphatase.

Universit£

Charting, navigating, and populating natural product chemical space for drug discovery.

Max Planck Institute Of Molecular Physiology

Dual-Specificity Phosphatase CDC25A/B Inhibitor Identified from a Focused Library with Nonelectrophilic Core Structure.

TBA

Arylstibonic acids are potent and isoform-selective inhibitors of Cdc25a and Cdc25b phosphatases.

Imperial College

Discovery of new inhibitors of Cdc25B dual specificity phosphatases by structure-based virtual screening.

Universit£

Syntheses and biological activities of a novel group of steroidal derived inhibitors for human Cdc25A protein phosphatase.

Georgia Institute Of Technology

Structure of protein tyrosine phosphatase 1B in complex with inhibitors bearing two phosphotyrosine mimetics.

University Of Waterloo

Synthesis of the novel analogues of dysidiolide and their structure-activity relationship.

The University Of Tokyo

Facile fabrication of promising protein tyrosine phosphatase (PTP) inhibitor entities based on 'clicked' serine/threonine-monosaccharide hybrids.

East China University Of Science And Technology

Using small molecules to target protein phosphatases.

Max Planck Institute Of Molecular Physiology

Synthesis and biological evaluation of novel coumarin-based inhibitors of Cdc25 phosphatases.

Université

Multidentate small-molecule inhibitors of vaccinia H1-related (VHR) phosphatase decrease proliferation of cervix cancer cells.

Institute For Medical Research

Structure-based virtual screening approach to identify novel classes of Cdc25B phosphatase inhibitors.

Sejong University

Structure-based de novo design and biochemical evaluation of novel Cdc25 phosphatase inhibitors.

Sejong University

 

Synthesis and phosphatase inhibitory activity of analogs of sulfircin

TBA

Discovery of novel Cdc25 phosphatase inhibitors with micromolar activity based on the structure-based virtual screening.

Sejong University

Design and synthesis of N-alkyl oxindolylidene acetic acids as a new class of potent Cdc25A inhibitors.

Doshisha Women'S College Of Liberal Arts

Synthesis and biological evaluation of dialkylsubstituted maleic anhydrides as novel inhibitors of Cdc25 dual specificity phosphatases.

Université

Brunsvicamides A-C: sponge-related cyanobacterial peptides with Mycobacterium tuberculosis protein tyrosine phosphatase inhibitory activity.

University Of Bonn

Synthesis of miltirone analogues as inhibitors of Cdc25 phosphatases.

Graduate School Of Chinese Academy Of Sciences

PTP-1B inhibitors: cyclopenta[d][1,2]-oxazine derivatives.

Korea Research Institute Of Chemical Technology

3-Substituted indolizine-1-carbonitrile derivatives as phosphatase inhibitors.

Technische UniversitäT MüNchen

Design and synthesis of novel Cdc25A-inhibitors having phosphate group as a hydrophilic residue.

The University Of Tokyo

Design and synthesis of dysidiolide analogs from vitamin D3: novel class of Cdc25A inhibitors.

The University Of Tokyo

Inhibition of Cdc25 phosphatases by indolyldihydroxyquinones.

Duke University

Synthesis of a novel class of cdc25A inhibitors from vitamin D3.

The University Of Tokyo

Dysidiolide and related gamma-hydroxy butenolide compounds as inhibitors of the protein tyrosine phosphatase, CDC25.

Mitotix

Novel CDC25A phosphatase inhibitors from pyrolysis of 3-alpha-azido-B-homo-6-oxa-4-cholesten-7-one on silica gel.

University Of Arizona

Alkyl and alkoxyethyl antineoplastic phospholipids.

National Hellenic Research Foundation

Structure-based development of novel triazoles and related thiazolotriazoles as anticancer agents and Cdc25A/B phosphatase inhibitors. Synthesis, in vitro biological evaluation, molecular docking and in silico ADME-T studies.

King Abdulaziz University

Novel coumarin- and quinolinone-based polycycles as cell division cycle 25-A and -C phosphatases inhibitors induce proliferation arrest and apoptosis in cancer cells.

Sapienza University Of Rome

Allosteric Inhibitors of SHP2 with Therapeutic Potential for Cancer Treatment.

Chinese Academy Of Sciences