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54 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Synthesis of benzothiadiazine derivatives exhibiting dual activity as aldose reductase inhibitors and antioxidant agents.EBI
Beijing Institute Of Technology
Phenolic Compounds from the Leaves and Twigs of Osteomeles schwerinae That Inhibit Rat Lens Aldose Reductase and Vessel Dilation in Zebrafish Larvae.EBI
Institute Of Oriental Medicine
Identification of novel aldose reductase inhibitors based on carboxymethylated mercaptotriazinoindole scaffold.EBI
Slovak Academy Of Sciences
Synthesis and biological evaluation of some new pyrazoline substituted benzenesulfonylurea/thiourea derivatives as anti-hyperglycaemic agents and aldose reductase inhibitors.EBI
Jamia Hamdard (Hamdard University)
Decreasing acidity in a series of aldose reductase inhibitors: 2-Fluoro-4-(1H-pyrrol-1-yl)phenol as a scaffold for improved membrane permeation.EBI
Aristotle University Of Thessaloniki
Synthesis and biological evaluation of new epalrestat analogues as aldose reductase inhibitors (ARIs).EBI
Csir-Indian Institute Of Chemical Technology
1-Hydroxypyrazole as a bioisostere of the acetic acid moiety in a series of aldose reductase inhibitors.EBI
Aristotle University Of Thessaloniki
Synthesis of derivatives of the keto-pyrrolyl-difluorophenol scaffold: some structural aspects for aldose reductase inhibitory activity and selectivity.EBI
Aristotle University Of Thessaloniki
QSAR prediction of inhibition of aldose reductase for flavonoids.EBI
Inifta (Unlp, Cct La Plata-Conicet)
Update on the development of antagonists of chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2). From lead optimization to clinical proof-of-concept in asthma and allergic rhinitis.EBI
Oxagen
Chemical constituents from the aerial parts of Aster koraiensis with protein glycation and aldose reductase inhibitory activities.EBI
Korean Institute Of Oriental Medicine (Kiom)
Inhibitors of aldose reductase and formation of advanced glycation end-products in moutan cortex (Paeonia suffruticosa).EBI
Chungnam National University
Erigeroflavanone, a flavanone derivative from the flowers of Erigeron annuus with protein glycation and aldose reductase inhibitory activity.EBI
Institute Of Oriental Medicine
Structures of new friedelane-type triterpenes and eudesmane-type sesquiterpene and aldose reductase inhibitors from Salacia chinensis.EBI
Kyoto Pharmaceutical University
Structural basis for the high all-trans-retinaldehyde reductase activity of the tumor marker AKR1B10.EBI
Universitat Aut£Noma De Barcelona
Substituted pyrrol-1-ylacetic acids that combine aldose reductase enzyme inhibitory activity and ability to prevent the nonenzymatic irreversible modification of proteins from monosaccharides.EBI
Aristotle University Of Thessaloniki
Molecular modeling studies of aldose reductase inhibitors.EBI
National Eye Institute
A highly specific aldose reductase inhibitor, ethyl 1-benzyl-3-hydroxy-2(5H)-oxopyrrole-4-carboxylate, and its congeners.EBI
Pfizer
Spiro[fluoreneisothiazolidin]one dioxides: new aldose reductase and L-hexonate dehydrogenase inhibitors.EBI
Alcon Laboratories
N- and 2-substituted N-(phenylsulfonyl)glycines as inhibitors of rat lens aldose reductase.EBI
Auburn University
Synthesis and rat lens aldose reductase inhibitory activity of some benzopyran-2-ones.EBI
TBA
Synthesis and aldose reductase inhibitory activity of substituted 2-oxoquinoline-1-acetic acid derivatives.EBI
TBA
Construction of an Indonesian herbal constituents database and its use in Random Forest modelling in a search for inhibitors of aldose reductase.EBI
King'S College London
Antidiabetogenic oligostilbenoids and 3-ethyl-4-phenyl-3,4-dihydroisocoumarins from the bark of Shorea roxburghii.EBI
Kinki University
1,2-Benzothiazine 1,1-dioxide carboxylate derivatives as novel potent inhibitors of aldose reductase.EBI
Beijing Institute Of Technology
Substituted indole-1-acetic acids as potent and selective CRTh2 antagonists-discovery of AZD1981.EBI
Astrazeneca R&D Charnwood
Structure-activity relations on [1-(3,5-difluoro-4-hydroxyphenyl)-1H-pyrrol-3-yl]phenylmethanone. The effect of methoxy substitution on aldose reductase inhibitory activity and selectivity.EBI
Aristotle University Of Thessaloniki
Acetic Acid Derivatives of 3,4-Dihydro-2H-1,2,4-benzothiadiazine 1,1-Dioxide as a Novel Class of Potent Aldose Reductase InhibitorsEBI
TBA
A diverse series of substituted benzenesulfonamides as aldose reductase inhibitors with antioxidant activity: design, synthesis, and in vitro activity.EBI
Aristotle University Of Thessaloniki
Synthesis and biological evaluation of [1,2,4]triazino[4,3-a] benzimidazole acetic acid derivatives as selective aldose reductase inhibitors.EBI
Institute Of Pharmaceutical Sciences
Design and synthesis of novel series of pyrrole based chemotypes and their evaluation as selective aldose reductase inhibitors. A case of bioisosterism between a carboxylic acid moiety and that of a tetrazole.EBI
Aristotle University Of Thessaloniki
Synthesis and biological activity of some new flavonyl-2,4-thiazolidinediones.EBI
Ankara University
Synthesis and aldose reductase inhibitory activity of some new chromonyl-2,4-thiazolidinediones.EBI
Ankara University
Design and synthesis of N-(3,5-difluoro-4-hydroxyphenyl)benzenesulfonamides as aldose reductase inhibitors.EBI
Aristotle University Of Thessaloniki
New flavonol oligoglycosides and polyacylated sucroses with inhibitory effects on aldose reductase and platelet aggregation from the flowers of Prunus mume.EBI
Kyoto Pharmaceutical University
Pyrido[1,2-a]pyrimidin-4-one derivatives as a novel class of selective aldose reductase inhibitors exhibiting antioxidant activity.EBI
Università
Discovery of potent CRTh2 (DP2) receptor antagonists.EBI
Astrazeneca R&D Charnwood
Structure of aldehyde reductase holoenzyme in complex with the potent aldose reductase inhibitor fidarestat: implications for inhibitor binding and selectivity.EBI
Monash University (Parkville Campus)
[1-(3,5-difluoro-4-hydroxyphenyl)-1H-pyrrol-3-yl]phenylmethanone as a bioisostere of a carboxylic acid aldose reductase inhibitor.EBI
Aristotle University Of Thessaloniki
Novel, highly potent aldose reductase inhibitors: cyano(2-oxo-2,3-dihydroindol-3-yl)acetic acid derivatives.EBI
Università
[1,2,4]Triazino[4,3-a]benzimidazole acetic acid derivatives: a new class of selective aldose reductase inhibitors.EBI
Università
A potent aldose reductase inhibitor, (2S,4S)-6-fluoro-2', 5'-dioxospiro[chroman-4,4'-imidazolidine]-2-carboxamide (Fidarestat): its absolute configuration and interactions with the aldose reductase by X-ray crystallography.EBI
Rational Drug Design Laboratories
Highly selective aldose reductase inhibitors. 3. Structural diversity of 3-(arylmethyl)-2,4,5-trioxoimidazolidine-1-acetic acids.EBI
Nippon Zoki Pharmaceutical
Highly selective aldose reductase inhibitors. 1. 3-(Arylalkyl)-2,4,5-trioxoimidazolidine-1-acetic acids.EBI
Nippon Zoki Pharmaceutical
Synthesis, absolute configuration, and conformation of the aldose reductase inhibitor sorbinil.EBI
TBA
Aldose reductase inhibitors: a potential new class of agents for the pharmacological control of certain diabetic complications.EBI
TBA
Novel inhibitors of rat lens aldose reductase: N-[[(substituted amino)phenyl]sulfonyl]glycines.EBI
TBA
Synthesis and biological evaluation of irreversible inhibitors of aldose reductase.EBI
TBA
Design and synthesis of 2-(arylamino)-4(3H)-quinazolinones as novel inhibitors of rat lens aldose reductase.EBI
TBA
Computer-assisted design and synthesis of novel aldose reductase inhibitors.EBI
Wyeth-Ayerst Research
Synthesis and in vitro aldose reductase inhibitory activity of compounds containing an N-acylglycine moiety.EBI
Auburn University
Relative structure-inhibition analyses of the N-benzoyl and N-(phenylsulfonyl) amino acid aldose reductase inhibitors.EBI
Auburn University
Novel, potent aldose reductase inhibitors: 3,4-dihydro-4-oxo-3-[[5-(trifluoromethyl)-2-benzothiazolyl] methyl]-1-phthalazineacetic acid (zopolrestat) and congeners.EBI
Pfizer
Selective irreversible inhibitors of aldose reductase.EBI
Ohio State University