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Synthesis and biological evaluation of a series of N-alkylated imidazole alkanoic acids as mGAT3 selective GABA uptake inhibitors.

Ludwig-Maximilians-Universit£T M£Nchen

Conformationally Restricted GABA with Bicyclo[3.1.0]hexane Backbone as the First Highly Selective BGT-1 Inhibitor.

Hokkaido University

Design, synthesis and SAR studies of GABA uptake inhibitors derived from 2-substituted pyrrolidine-2-yl-acetic acids.

Ludwig-Maximilians-Universit£T M£Nchen

The lignan (-)-hinokinin displays modulatory effects on human monoamine and GABA transporter activities.

Drexel University College Of Medicine

Cyclopropane-based conformational restriction of GABA by a stereochemical diversity-oriented strategy: identification of an efficient lead for potent inhibitors of GABA transports.

Hokkaido University

Synthesis of N-substituted acyclicß-amino acids and their investigation as GABA uptake inhibitors.

Zentrum F£R Pharmaforschung

Aminomethyltetrazoles as potential inhibitors of the¿-aminobutyric acid transporters mGAT1-mGAT4: synthesis and biological evaluation.

Ludwig-Maximilians-University Munich

Design, synthesis, and biological evaluation of the N-diarylalkenyl-piperidinecarboxylic acid derivatives as GABA uptake inhibitors (I).

Fudan University

Development of imidazole alkanoic acids as mGAT3 selective GABA uptake inhibitors.

Ludwig-Maximilians-University Munich

Stereospecific synthesis and structure-activity relationships of unsymmetrical 4,4-diphenylbut-3-enyl derivatives of nipecotic acid as GAT-1 inhibitors.

Glaxosmithkline

Azetidine derivatives as novel gamma-aminobutyric acid uptake inhibitors: synthesis, biological evaluation, and structure-activity relationship.

Zentrum F£R Pharmaforschung

 

On the bioactive conformation of the gaba uptake inhibitor SK&F 89976-A

TBA

Screening oxime libraries by means of mass spectrometry (MS) binding assays: Identification of new highly potent inhibitors to optimized inhibitors ?-aminobutyric acid transporter 1.

Ludwig-Maximilians-University M£Nchen

Five-Membered N-Heterocyclic Scaffolds as Novel Amino Bioisosteres at ?-Aminobutyric Acid (GABA) Type A Receptors and GABA Transporters.

University Of Copenhagen

Novel Allosteric Ligands of ?-Aminobutyric Acid Transporter 1 (GAT1) by MS Based Screening of Pseudostatic Hydrazone Libraries.

Ludwig-Maximilians-Universit£T M£Nchen

Design, synthesis and evaluation of substituted triarylnipecotic acid derivatives as GABA uptake inhibitors: identification of a ligand with moderate affinity and selectivity for the cloned human GABA transporter GAT-3.

Synaptic Pharmaceutical

Structure-Activity Relationship, Pharmacological Characterization, and Molecular Modeling of Noncompetitive Inhibitors of the Betaine/?-Aminobutyric Acid Transporter 1 (BGT1).

University Of Copenhagen