36 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
A novel class of potent nonglycosidic and nonpeptidic pan-selectin inhibitors.
Johannes Gutenberg University
Is adamantane a suitable substituent to pre-organize the acid orientation in E-selectin antagonists?
University Of Basel
Rational design of novel, potent small molecule pan-selectin antagonists.
Revotar Biopharmaceuticals
Synthesis and biological evaluation of sialylmimetics as rotavirus inhibitors.
Griffith University (Gold Coast Campus)
Development of potent non-carbohydrate imidazole-based small molecule selectin inhibitors with antiinflammatory activity.
Ontogen
Novel synthetic inhibitors of selectin-mediated cell adhesion: synthesis of 1,6-bis[3-(3-carboxymethylphenyl)-4-(2-alpha-D- mannopyranosyloxy)phenyl]hexane (TBC1269).
Texas Biotechnology
Studies on selectin blockers. 7. Structure-activity relationships of sialyl Lewis X mimetics based on modified Ser-Glu dipeptides.
Kanebo
Studies on selectin blockers. 6. Discovery of homologous fucose sugar unit necessary for E-selectin binding.
Kanebo
Studies on selectin blocker. 1. Structure-activity relationships of sialyl Lewis X analogs.
Institute Of Cancer Research
Studies on selectin blockers. 2. Novel selectin blocker as potential therapeutics for inflammatory disorders.
New Drug Research Laboratory
Rational design and synthesis of small molecule, non-oligosaccharide selectin inhibitors: (alpha-D-mannopyranosyloxy)biphenyl-substituted carboxylic acids.
Texas Biotechnology
Design and synthesis of a new sialyl Lewis X mimetic: how selective are the selectin receptors?
Universit£
Synthesis of sialyl Lewis(x) mimics. Modifications of the 6-position of galactose.
Novartis Pharma
Synthesis of novel sialylmimetics as biological probes.
Monash University (Parkville Campus)
Exploration of beta-turn scaffolding motifs as components of sialyl Le(X) mimetics and their relevance to P-selectin.
Universit£
Synthesis of sialyl Lewis X mimetics using the Ugi four-component reaction.
Scripps Research Institute
Synthesis and inhibitory effects of bivalent sialyl lewis X analogs at preventing cell adhesion
TBA
Synthesis and biological activity of conformationally constrained sialyl Lewis X analogues with reduced carbohydrate character
TBA
Synthesis of fluorinated C-mannopeptides as sialyl Lewisx mimics for E- and P-selectin inhibition.
Universit£
Sialyl Lewis(x) analogs based on a quinic acid scaffold as the fucose mimic.
National Chemical Engineering Institute In Paris
Selective inhibition of ICAM-1 and E-selectin expression in human endothelial cells. 2. Aryl modifications of 4-(aryloxy)thieno[2,3-c]pyridines with fine-tuning at C-2 carbamides.
Abbott Laboratories
Discovery of inhibitors of cell adhesion molecule expression in human endothelial cells. 1. Selective inhibition of ICAM-1 and E-selectin expression.
Abbott Laboratories
Synthesis and biological evaluation of a sialyl Lewis X mimic with significantly improved E-selectin inhibition.
Novartis Pharma
Selectin-ligand interactions revealed by molecular dynamics simulation in solution.
Kanebo
Ligand interactions with E-selectin. Identification of a new binding site for recognition of N-acyl aromatic glucosamine substituents of sialyl Lewis X.
Cytel
3-Alkoxybenzo[b]thiophene-2-carboxamides as inhibitors of neutrophil-endothelial cell adhesion.
Warner-Lambert