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8 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Novel, broad-spectrum anticonvulsants containing a sulfamide group: advancement of N-((benzo[b]thien-3-yl)methyl)sulfamide (JNJ-26990990) into human clinical studies.EBI
Johnson & Johnson Pharmaceutical Research & Development
Synthesis and pharmacological evaluation of N,N'-diarylguanidines as potent sodium channel blockers and anticonvulsant agents.EBI
Cambridge Neuroscience
Design, synthesis, and pharmacological evaluation of conformationally constrained analogues of N,N'-diaryl- and N-aryl-N-aralkylguanidines as potent inhibitors of neuronal Na+ channels.EBI
Cambridge Neuroscience
Synthesis and pharmacological evaluation of phenylacetamides as sodium-channel blockers.EBI
Warner-Lambert
Lactam-stabilized helical analogues of the analgesicµ-conotoxin KIIIA.EBI
Monash University
Discovery and stereoselective synthesis of the novel isochroman neurokinin-1 receptor antagonist 'CJ-17,493'.EBI
Pfizer
Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels.EBI
University Of Utah
A structure-activity relationship study of novel phenylacetamides which are sodium channel blockers.EBI
Warner-Lambert