13 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
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Studies examining the relationship between the chemical structure of protoxin II and its activity on voltage gated sodium channels.
Purdue Pharma
Novel, broad-spectrum anticonvulsants containing a sulfamide group: advancement of N-((benzo[b]thien-3-yl)methyl)sulfamide (JNJ-26990990) into human clinical studies.
Johnson & Johnson Pharmaceutical Research & Development
Synthesis and pharmacological evaluation of N,N'-diarylguanidines as potent sodium channel blockers and anticonvulsant agents.
Cambridge Neuroscience
Design, synthesis, and pharmacological evaluation of conformationally constrained analogues of N,N'-diaryl- and N-aryl-N-aralkylguanidines as potent inhibitors of neuronal Na+ channels.
Cambridge Neuroscience
Synthesis and pharmacological evaluation of phenylacetamides as sodium-channel blockers.
Warner-Lambert
Lactam-stabilized helical analogues of the analgesicµ-conotoxin KIIIA.
Monash University
Discovery and stereoselective synthesis of the novel isochroman neurokinin-1 receptor antagonist 'CJ-17,493'.
Pfizer
Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels.
University Of Utah