The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 2.8M data for 1.2M Compounds and 9.2K Targets. Of those, 1,339K data for 617K Compounds and 4.5K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

If BindingDB was of value to your research, please take a moment to donate to this nonprofit project. Your donation will let us provide you with more data and improved service.

Advanced Search

28 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Discovery and Synthesis of C-Nucleosides as Potential New Anti-HCV Agents.EBI
Biota Scientific Management
New nucleotide-competitive non-nucleoside inhibitors of terminal deoxynucleotidyl transferase: discovery, characterization, and crystal structure in complex with the target.EBI
Sapienza University Of Rome
8-Benzamidochromen-4-one-2-carboxylic acids: potent and selective agonists for the orphan G protein-coupled receptor GPR35.EBI
University Of Bonn
Selective inhibition of the tumor marker aldo-keto reductase family member 1B10 by oleanolic acid.EBI
Gifu Pharmaceutical University
Alpha,beta-methylene-2'-deoxynucleoside 5'-triphosphates as noncleavable substrates for DNA polymerases: isolation, characterization, and stability studies of novel 2'-deoxycyclonucleosides, 3,5'-cyclo-dG, and 2,5'-cyclo-dT.EBI
University Of Rhode Island
A new acylated oleanane triterpenoid from Couepia polyandra that inhibits the lyase activity of DNA polymerase beta.EBI
Virginia Polytechnic Institute And State University
Specific inhibition of human immunodeficiency virus type 1 reverse transcriptase mediated by soulattrolide, a coumarin isolated from the latex of calophyllum teysmannii.EBI
Chulalongkorn University
Inhibitors of DNA polymerase beta: activity and mechanism.EBI
University Of Virginia
Newly synthesized L-enantiomers of 3'-fluoro-modified beta-2'-deoxyribonucleoside 5'-triphosphates inhibit hepatitis B DNA polymerases but not the five cellular DNA polymerases alpha, beta, gamma, delta, and epsilon nor HIV-1 reverse transcriptase.EBI
Max-Delbr�Ck-Centrum F�R Molekulare Medizin
1,5-benzodiazepines, a novel class of hepatitis C virus polymerase nonnucleoside inhibitors.EBI
Tibotec
GS-9191 is a novel topical prodrug of the nucleotide analog 9-(2-phosphonylmethoxyethyl)guanine with antiproliferative activity and possible utility in the treatment of human papillomavirus lesions.EBI
Gilead Sciences
PSI-7851, a pronucleotide of beta-D-2'-deoxy-2'-fluoro-2'-C-methyluridine monophosphate, is a potent and pan-genotype inhibitor of hepatitis C virus replication.EBI
Pharmasset
N-sulfonylanthranilic acid derivatives as allosteric inhibitors of dengue viral RNA-dependent RNA polymerase.EBI
Novartis Institute For Tropical Diseases
Differential Inhibition of Reverse Transcriptase and Various DNA Polymerases by Digallic Acid and Its DerivativesEBI
TBA
Mechanistic Evaluation of New Plant-Derived Compounds That Inhibit HIV-1 Reverse TranscriptaseEBI
TBA
Hymenoic acid, a novel specific inhibitor of human DNA polymerase lambda from a fungus of Hymenochaetaceae sp.EBI
Kobe Gakuin University
Acylphloroglucinol derivatives from Mahurea palustris.EBI
National Center For Scientific Research (Cnrs)-Pierre Fabre
Marine sesquiterpenoids that inhibit the lyase activity of DNA polymerase beta.EBI
Virginia Polytechnic Institute And State University
New neolignans that inhibit DNA polymerase beta lyase.EBI
Virginia Polytechnic Institute And State University
A new ursane triterpene from Monochaetum vulcanicum that inhibits DNA polymerase beta lyase.EBI
Virginia Polytechnic Institute And State University
Benzimidazole derivatives bearing substituted biphenyls as hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitors: structure-activity relationship studies and identification of a potent and highly selective inhibitor JTK-109.EBI
Central Pharmaceutical Research Institute
Discovery of proline sulfonamides as potent and selective hepatitis C virus NS5b polymerase inhibitors. Evidence for a new NS5b polymerase binding site.EBI
Wyeth Research
Synthetic analogues of the manzamenones and plakoridines which inhibit DNA polymerase.EBI
The University Of Manchester
Benzimidazole inhibitors of hepatitis C virus NS5B polymerase: identification of 2-[(4-diarylmethoxy)phenyl]-benzimidazole.EBI
Central Pharmaceutical Research Institute
3-(1,1-dioxo-2H-(1,2,4)-benzothiadiazin-3-yl)-4-hydroxy-2(1H)-quinolinones, potent inhibitors of hepatitis C virus RNA-dependent RNA polymerase.EBI
Glaxosmithkline
Discovery of pyrano[3,4-b]indoles as potent and selective HCV NS5B polymerase inhibitors.EBI
Wyeth Research
Identification of [(naphthalene-1-carbonyl)-amino]-acetic acid derivatives as nonnucleoside inhibitors of HCV NS5B RNA dependent RNA polymerase.EBI
Wyeth Research