40 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Identification, synthesis and evaluation of SARS-CoV and MERS-CoV 3C-like protease inhibitors.
Academia Sinica
X-ray structural and biological evaluation of a series of potent and highly selective inhibitors of human coronavirus papain-like proteases.
Purdue University
Virtual screening identification of novel severe acute respiratory syndrome 3C-like protease inhibitors and in vitro confirmation.
Chonnam National University
Investigation of the pharmacophore space of Severe Acute Respiratory Syndrome coronavirus (SARS-CoV) NTPase/helicase by dihydroxychromone derivatives.
Konkuk University
Aryl diketoacids (ADK) selectively inhibit duplex DNA-unwinding activity of SARS coronavirus NTPase/helicase.
Konkuk University
Identification of novel drug scaffolds for inhibition of SARS-CoV 3-Chymotrypsin-like protease using virtual and high-throughput screenings.
University Of Illinois At Chicago
Synthesis, modification and docking studies of 5-sulfonyl isatin derivatives as SARS-CoV 3C-like protease inhibitors.
Tianjin University Of Science And Technology
Design, synthesis, and bioevaluation of viral 3C and 3C-like protease inhibitors.
Kansas State University
Dieckol, a SARS-CoV 3CL(pro) inhibitor, isolated from the edible brown algae Ecklonia cava.
Korea Research Institute Of Bioscience And Biotechnology
Design, synthesis and crystallographic analysis of nitrile-based broad-spectrum peptidomimetic inhibitors for coronavirus 3C-like proteases.
The Chinese University Of Hong Kong
Synthesis and evaluation of pyrazolone compounds as SARS-coronavirus 3C-like protease inhibitors.
Academia Sinica
Biflavonoids from Torreya nucifera displaying SARS-CoV 3CL(pro) inhibition.
Korea Research Institute Of Bioscience And Biotechnology
SARS-CoV 3CLpro inhibitory effects of quinone-methide triterpenes from Tripterygium regelii.
Korea Research Institute Of Bioscience And Biotechnology
Quantitative high-throughput screening identifies inhibitors of anthrax-induced cell death.
National Human Genome Research Institute
New developments for the design, synthesis and biological evaluation of potent SARS-CoV 3CL(pro) inhibitors.
Kyoto Pharmaceutical University
Novel small-molecule inhibitors of transmissible gastroenteritis virus.
National Health Research Institute
Structure-based design, synthesis, and biological evaluation of peptidomimetic SARS-CoV 3CLpro inhibitors.
Purdue University
Structure-guided design of potent and permeable inhibitors of MERS coronavirus 3CL protease that utilize a piperidine moiety as a novel design element.
Wichita State University
Discovery of S-217622, a Non-Covalent Oral SARS-CoV-2 3CL Protease Inhibitor Clinical Candidate for Treating COVID-19
Shionogi Pharmaceutical Research Center
A patent review on SARS coronavirus main protease (3CLpro) inhibitors.
Experimental Drug Development Centre
Rational Design of Hybrid SARS-CoV-2 Main Protease Inhibitors Guided by the Superimposed Cocrystal Structures with the Peptidomimetic Inhibitors GC-376, Telaprevir, and Boceprevir.
The University Of Arizona
Structure-Based Optimization of ML300-Derived, Noncovalent Inhibitors Targeting the Severe Acute Respiratory Syndrome Coronavirus 3CL Protease (SARS-CoV-2 3CL
Cleveland Clinic
A head-to-head comparison of the inhibitory activities of 15 peptidomimetic SARS-CoV-2 3CLpro inhibitors.
A*Star
Identification of inhibitors of SARS-CoV-2 3CL-Pro enzymatic activity using a small molecule in-vitro repurposing screen
Fraunhofer Institute For Translational Medicine And Pharmacology (Itmp) And Fraunhofer Cluster Of Excellence For Immune Mediated Diseases (Cimd
The recent outbreaks of human coronaviruses: A medicinal chemistry perspective.
University Of Bonn
An Overview of Severe Acute Respiratory Syndrome-Coronavirus (SARS-CoV) 3CL Protease Inhibitors: Peptidomimetics and Small Molecule Chemotherapy.
University Of Bonn
Structural basis of inhibition specificities of 3C and 3C-like proteases by zinc-coordinating and peptidomimetic compounds.
National Yang-Ming University
Stable benzotriazole esters as mechanism-based inactivators of the severe acute respiratory syndrome 3CL protease.
Academia Sinica
Structure-based virtual screening against SARS-3CL(pro) to identify novel non-peptidic hits.
University Of Mississippi
Structure-based drug design and structural biology study of novel nonpeptide inhibitors of severe acute respiratory syndrome coronavirus main protease.
National Defense Medical Center
Discovery of a novel family of SARS-CoV protease inhibitors by virtual screening and 3D-QSAR studies.
National Tsing Hua University
Inhibition of the severe acute respiratory syndrome 3CL protease by peptidomimetic alpha,beta-unsaturated esters.
National Taiwan University
Discovery of potent anilide inhibitors against the severe acute respiratory syndrome 3CL protease.
National Taiwan University