The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 2.8M data for 1.2M Compounds and 9.2K Targets. Of those, 1,346K data for 622K Compounds and 4.5K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

If BindingDB was of value to your research, please take a moment to donate to this nonprofit project. Your donation will let us provide you with more data and improved service.

Advanced Search

40 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Synthesis and evaluation of N-(benzofuran-5-yl)aromaticsulfonamide derivatives as novel HIF-1 inhibitors that possess anti-angiogenic potential.EBI
China Pharmaceutical University
Screening and Biological Effects of Marine Pyrroloiminoquinone Alkaloids: Potential Inhibitors of the HIF-1a/p300 Interaction.EBI
National Cancer Institute-Frederick
Isoform-Selective and Stereoselective Inhibition of Hypoxia Inducible Factor-2.EBI
University Of Texas Southwestern Medical Center
Bioactive benzofuran derivatives: moracins A-Z in medicinal chemistry.EBI
Dongguk University-Seoul
Synthesis and structure-activity relationship study of chemical probes as hypoxia induced factor-1a/malate dehydrogenase 2 inhibitors.EBI
Dongguk University-Seoul
A perylene derivative regulates HIF-1a and Stat3 signaling pathways.EBI
Baylor College Of Medicine
Discovery of Indenopyrazoles as a New Class of Hypoxia Inducible Factor (HIF)-1 Inhibitors.EBI
Gakushuin University
Recent advances in hypoxia-inducible factor (HIF)-1 inhibitors.EBI
Dongguk University-Seoul
Synthesis and structure-activity relationship of (E)-phenoxyacrylic amide derivatives as hypoxia-inducible factor (HIF) 1a inhibitors.EBI
Dongguk University-Seoul
Discovery of a new molecular probe ML228: an activator of the hypoxia inducible factor (HIF) pathway.EBI
The Broad Institute Probe Development Center
Joys of molecules. 2. Endeavors in chemical biology and medicinal chemistry.EBI
The Scripps Research Institute
Synthesis and evaluation of quinazolin-4-ones as hypoxia-inducible factor-1a inhibitors.EBI
National Human Genome Research Institute
HIF-1a inhibitors: synthesis and biological evaluation of novel moracin O and P analogues.EBI
Dongguk University-Seoul
1-[4-(N-Benzylamino)phenyl]-3-phenylurea derivatives as a new class of hypoxia-inducible factor-1alpha inhibitors.EBI
Gakushuin University
Development of novel inhibitors targeting HIF-1a towards anticancer drug discovery.EBI
Piramal Life Sciences
Boron-containing phenoxyacetanilide derivatives as hypoxia-inducible factor (HIF)-1alpha inhibitors.EBI
Gakushuin University
HIF-1alpha peptide derivatives with modifications at the hydroxyproline residue as activators of HIF-1alpha.EBI
Institute Of Science And Technology
Total synthesis and absolute configuration of laurenditerpenol: a hypoxia inducible factor-1 activation inhibitor.EBI
University Of Mississippi. University
Synthesis of (aryloxyacetylamino)-isonicotinic/nicotinic acid analogues as potent hypoxia-inducible factor (HIF)-1alpha inhibitors.EBI
Molecular Cancer Research Center
Benzo[EBI
Fudan University
Design, synthesis of novel celastrol derivatives and study on their antitumor growth through HIF-1? pathway.EBI
Yanbian University
Design, synthesis, and target identification of new hypoxia-inducible factor 1 (HIF-1) inhibitors containing 1-alkyl-1H-pyrazole-3-carboxamide moiety.EBI
Kyoto University
Total synthesis and biological evaluation of 7-hydroxyneolamellarin A as hypoxia-inducible factor-1? inhibitor for cancer therapy.EBI
Dalian University Of Technology
Synthesis and evaluation of HIF-1? inhibitory activities of novel panaxadiol derivatives.EBI
Yanbian University
Design, synthesis, and evaluation of indeno[2,1-c]pyrazolones for use as inhibitors against hypoxia-inducible factor (HIF)-1 transcriptional activity.EBI
Tokyo Institute Of Innovative Research
Advances in inhibition of protein-protein interactions targeting hypoxia-inducible factor-1 for cancer therapy.EBI
China Pharmaceutical University
Small-Molecule Modulators of the Hypoxia-Inducible Factor Pathway: Development and Therapeutic Applications.EBI
China Pharmaceutical University
Synthesis and evaluation of the HIF-1? inhibitory activities of novel ursolic acid tetrazole derivatives.EBI
Yanbian University College Of Pharmacy
Design, synthesis, and screening of novel ursolic acid derivatives as potential anti-cancer agents that target the HIF-1? pathway.EBI
Yanbian University College Of Pharmacy
Discovery of Novel Aryl Carboxamide Derivatives as Hypoxia-Inducible Factor 1? Signaling Inhibitors with Potent Activities of Anticancer Metastasis.EBI
Anhui Medical University
Small molecules targeting HIF-1? pathway for cancer therapy in recent years.EBI
Shandong University
An isoaurone and other constituents from Trichosanthes kirilowii seeds inhibit hypoxia-inducible factor-1 and nuclear factor-kappaB.EBI
Korean Research Institute Of Biosciences And Biotechnology
Hypoxia-inducible factor-1 inhibitory benzofurans and chalcone-derived diels-alder adducts from Morus species.EBI
Korean Research Institute Of Biosciences And Biotechnology
Novel Hypoxia-Inducible Factor 1? (HIF-1?) Inhibitors for Angiogenesis-Related Ocular Diseases: Discovery of a Novel Scaffold via Ring-Truncation Strategy.EBI
Seoul National University
Synthesis and biological evaluation of kresoxim-methyl analogues as novel inhibitors of hypoxia-inducible factor (HIF)-1 accumulation in cancer cells.EBI
Yeungnam University
Methyl 3-(3-(4-(2,4,4-Trimethylpentan-2-yl)phenoxy)-propanamido)benzoate as a Novel and Dual Malate Dehydrogenase (MDH) 1/2 Inhibitor Targeting Cancer Metabolism.EBI
Dongguk University
Utilization of an in vivo reporter for high throughput identification of branched small molecule regulators of hypoxic adaptation.BDB
Weill Medical College Of Cornell University