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10 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Application of encoded library technology (ELT) to a protein-protein interaction target: discovery of a potent class of integrin lymphocyte function-associated antigen 1 (LFA-1) antagonists.EBI
Glaxosmithkline
Design, synthesis, and functional evaluation of leukocyte function associated antigen-1 antagonists in early and late stages of cancer development.EBI
Ikerchem
Discovery of tetrahydroisoquinoline (THIQ) derivatives as potent and orally bioavailable LFA-1/ICAM-1 antagonists.EBI
Sunesis Pharmaceuticals
Small molecule antagonist of leukocyte function associated antigen-1 (LFA-1): structure-activity relationships leading to the identification of 6-((5S,9R)-9-(4-cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]nonan-7-yl)nicotinic acid (BMS-688521).EBI
Bristol-Myers Squibb Research And Development
Cucurbitacins, Cell Adhesion Inhibitors from Conobea scoparioidesEBI
TBA
Four new clerodane diterpenes from the leaves of Casearia guianensis which inhibit the interaction of leukocyte function antigen 1 with intercellular adhesion molecule 1.EBI
Searle Research And Development
Structure-activity relationship of ortho- and meta-phenol based LFA-1 ICAM inhibitors.EBI
Biogen Idec
Design and synthesis of a series of meta aniline-based LFA-1 ICAM inhibitors.EBI
Biogen Idec
Discovery of novel p-arylthio cinnamides as antagonists of leukocyte function-associated antigen-1/intercellular adhesion molecule-1 interaction. 4. Structure-activity relationship of substituents on the benzene ring of the cinnamide.EBI
Abbott Laboratories
Antiparasitic alkaloids from Psychotria klugii.EBI
University Of Mississippi