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35 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
722731 1 Prodrugs of 9-beta-D-arabinofuranosyladenine. 1. Synthesis and evaluation of some 5'-(O-acyl) derivatives.EBI TBA
10450967 4 The design and synthesis of inhibitors of adenosine 5'-monophosphate deaminase.EBI AgrEvo UK Limited
21138280 33 Investigations into the origin of the molecular recognition of several adenosine deaminase inhibitors.EBI Bar-Ilan University
16078836 13 Novel, highly potent adenosine deaminase inhibitors containing the pyrazolo[3,4-d]pyrimidine ring system. Synthesis, structure-activity relationships, and molecular modeling studies.EBI Universit£ di Pisa
14761206 10 Inhibition of adenosine deaminase by novel 5:7 fused heterocycles containing the imidazo[4,5-e][1,2,4]triazepine ring system: a structure-activity relationship study.EBI University of Maryland
11606136 10 Design, synthesis, and biological evaluation of novel nucleoside and nucleotide analogues as agents against DNA viruses and/or retroviruses.EBI Institute of Chemistry
11101360 14 Adenosine deaminase inhibitors: synthesis and biological evaluation of unsaturated, aromatic, and oxo derivatives of (+)-erythro-9-(2'S-hydroxy-3'R-nonyl)adenine [(+)-EHNA].EBI University of Rhode Island
9397178 1 Enzymatic properties of the unnatural beta-L-enantiomers of 2',3'-dideoxyadenosine and 2',3'-didehydro-2',3'-dideoxyadenosine.EBI Universit£ Montpellier-2 des Sciences et Techniques du Languedoc
7562937 48 Synthesis and biological evaluation of N6-cycloalkyl derivatives of 1-deazaadenine nucleosides: a new class of anti-human immunodeficiency virus agents.EBI Universit£ di Camerino
8289197 20 Adenosine deaminase inhibitors: synthesis and structure-activity relationships of 2-hydroxy-3-nonyl derivatives of azoles.EBI Universit£ di Camerino
1433220 12 Adenosine deaminase inhibitors. Synthesis and biological evaluation of C1' and nor-C1' derivatives of (+)-erythro-9-(2(S)-hydroxy-3(R)-nonyl)adenine.EBI University of Rhode Island
2066996 4 Purine and 1-deazapurine ribonucleosides and deoxyribonucleosides: synthesis and biological activity.EBI Universit£ di Camerino
2002459 28 Adenosine deaminase inhibitors: synthesis and structure-activity relationships of imidazole analogues of erythro-9-(2-hydroxy-3-nonyl)adenine.EBI Universit£ di Camerino
3339608 10 Adenosine deaminase inhibitors. Synthesis and biological activity of deaza analogues of erythro-9-(2-hydroxy-3-nonyl)adenine.EBI Universit£ di Camerino
3585903 2 Synthesis, structure, and biological activity of certain 2-deoxy-beta-D-ribo-hexopyranosyl nucleosides and nucleotides.EBI TBA
4068002 2 Study on the inhibition of adenosine deaminase.EBI TBA
6699873 10 Adenosine deaminase inhibitors. Synthesis of deaza analogues of erythro-9-(2-hydroxy-3-nonyl)adenine.EBI TBA
6604819 5 Adenosine deaminase inhibitors. Synthesis and biological evaluation of (+/-)-3,6,7,8-tetrahydro-3-[(2-hydroxyethoxy)methyl]imidazo[4,5-d] [1,3]diazepin-8-ol and some selected C-5 homologues of pentostatin.EBI TBA
11677121 4 A unique ring-expanded acyclic nucleoside analogue that inhibits both adenosine deaminase (ADA) and guanine deaminase (GDA; guanase): synthesis and enzyme inhibition studies of 4,6-diamino-8H-1-hydroxyethoxymethyl-8-iminoimidazo[4,5-e][1,3]diazepine.EBI University of Maryland
11356110 2 Synthesis and biological evaluation of purine-containing butenolides.EBI Institute of Chemistry
11170651 47 AMP deaminase inhibitors. 5. Design, synthesis, and SAR of a highly potent inhibitor series.EBI Metabasis Therapeutics Inc.
10780908 40 AMP deaminase inhibitors. 4. Further N3-substituted coformycin aglycon analogues: N3-alkylmalonates as ribose 5'-monophosphate mimetics.EBI Metabasis Therapeutics Inc.
10780907 63 AMP deaminase inhibitors. 3. SAR of 3-(carboxyarylalkyl)coformycin aglycon analogues.EBI Metabasis Therapeutics Inc.
10780906 94 AMP deaminase inhibitors. 2. Initial discovery of a non-nucleotide transition-state inhibitor series.EBI Metabasis Therapeutics Inc.
9873405 9 Adenosine deaminase inhibitors. Synthesis and biological evaluation of aralkyladenines (ARADS).EBI University of Rhode Island
9341908 2 Effect of a chemical modification on the hydrated adenosine intermediate produced by adenosine deaminase and a model reaction for a potential mechanism of action of 5-aminoimidazole ribonucleotide carboxylase.EBI Southern Illinois University
8295218 3 Adenosine deaminase inhibitors. Synthesis and biological evaluation of 4-amino-1-(2(S)-hydroxy-3(R)-nonyl)-1H-imidazo[4,5-c]pyridine (3-deaza-(+)-EHNA) and certain C1' derivatives.EBI University of Rhode Island
7966142 4 Adenosine deaminase inhibitors. Synthesis and biological evaluation of putative metabolites of (+)-erythro-9-(2S-hydroxy-3R-nonyl)adenine.EBI University of Rhode Island
7473592 2 Design, synthesis, and structure-activity relationship of novel dinucleotide analogs as agents against herpes and human immunodeficiency viruses.EBI Institute of Chemistry
7401106 18 Heat-induced formation of alpha,beta-unsaturated nucleoside dialdehydes and their activity with adenosine deaminase.EBI TBA
7086847 4 Inhibitors of adenosine deaminase. Studies in combining high-affinity enzyme-binding structural units. erythro-1,6-Dihydro-6-(hydroxymethyl)-9-(2-hydroxy-3-nonyl)purine and erythro-9-(2-hydroxy-3-nonyl)purine.EBI TBA
6965728 5 Binding specificities of adenosine aminohydrolase from calf intestinal mucosa with dialdehydes derived from hexofuranosyladenine nucleosides.EBI TBA
19226143 17 Exploiting the pyrazolo[3,4-d]pyrimidin-4-one ring system as a useful template to obtain potent adenosine deaminase inhibitors.BDB Universita di Pisa
18173230 5 Inhibition of adenosine deaminase by analogues of adenosine and inosine, incorporating a common heterocyclic base, 4(7)-amino-6(5)H-imidazo[4,5-d]pyridazin-7(4)one.BDB University of Maryland Baltimore County