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68 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
27004954 8 Synthesis and evaluation of novel angiotensin II receptor 1 antagonists as anti-hypertension drugs.EBI Donghua University
25699147 6 Interconversion of Functional Activity by Minor Structural Alterations in Nonpeptide AT2 Receptor Ligands.EBI Uppsala University
15509155 5 NO-sartans: a new class of pharmacodynamic hybrids as cardiovascular drugs.EBI Universit£ di Pisa
19013821 12 Design, synthesis, and evaluation of 5-sulfamoyl benzimidazole derivatives as novel angiotensin II receptor antagonists.EBI Punjabi University
18158200 10 Angiotensin II--AT1 receptor antagonists: design, synthesis and evaluation of substituted carboxamido benzimidazole derivatives.EBI Punjabi University
9379447 20 Angiotensin analogues palmitoylated in positions 1 and 4.EBI Universit£ de Sherbrooke
 19 Substituted lactam biphenyltetrazoles as angiotensin II mediated antihypertensivesEBI TBA
 40 Synthesis and In Vitro evaluation of fused ring heterocyle-containing angiotensin II antagonists.EBI TBA
22727371 22 Design, synthesis and biological activity of 6-substituted carbamoyl benzimidazoles as new nonpeptidic angiotensin II AT1 receptor antagonists.EBI School of Chemical Engineering& the Environment
20073471 15 Design, synthesis, and docking studies of novel benzimidazoles for the treatment of metabolic syndrome.EBI The University of Mississippi
18318468 39 Design, synthesis, and biological evaluation of AT1 angiotensin II receptor antagonists based on the pyrazolo[3,4-b]pyridine and related heteroaromatic bicyclic systems.EBI Universit£ di Siena
10821712 18 Quantized surface complementarity diversity (QSCD): a model based on small molecule-target complementarity.EBI NeoGenesis, Inc.
8576904 78 Nonpeptide angiotensin II receptor antagonists: the next generation in antihypertensive therapy.EBI DuPont Merck Pharmaceutical Company
8410980 9 2-(Alkylamino)nicotinic acid and analogs. Potent angiotensin II antagonists.EBI Abbott Laboratories
8340909 14 Excursions in drug discovery.EBI Merck Research Laboratories
 32 L-161,638: A potent AT2selective quinazolinone angiotensin II binding inhibitorEBI TBA
 17 (6-oxo-3-pyridazinyl)-benzimidazoles as potent angiotensin II receptor antagonistsEBI TBA
22264484 28 Synthesis and antihypertensive activity of pyrimidin-4(3H)-one derivatives as losartan analogue for new angiotensin II receptor type 1 (AT1) antagonists.EBI Kyung Hee University
22309912 28 Design, synthesis and biological evaluation of 6-substituted aminocarbonyl benzimidazole derivatives as nonpeptidic angiotensin II AT1 receptor antagonists.EBI Beijing Institute of Technology
21071232 78 Angiotensin II receptor type 1 (AT1) selective nonpeptidic antagonists--a perspective.EBI The M. S. University of Baroda
 24 The design, binding affinity prediction and synthesis of macrocyclic angiotensin II AT1 and AT2 receptor antagonistsEBI TBA
 10 L-162,389: a potent orally active angiotensin II receptor antagonist with balanced affinity to both AT1 and AT2 receptor subtypesEBI TBA
 17 AT1 selective angiotensin II antagonists with phenoxyphenylacetic acid as a biphenyl replacement part IEBI TBA
 60 The SAR of 6-(N-alkyl-N-acyl)-2-propyl-3-[(2′-tetrazol-5-yl)biphen-4-yl)methyl]-quinazolinones as balanced affinity antagonists of the human AT1 and AT2 receptorsEBI TBA
 54 α-Phenoxyphenylacetic acid derived angiotensin II antagonists with low nanomolar AT1/AT2 receptor subtype affinity (Part II)EBI TBA
 8 Substituted 1,3-benzodioxole & 1,3-benzodithiole -2- carboxylates and their tetrazole analogs with potent binding affinity to the angiotensin II AT1 receptorEBI TBA
 56 Potent triazolinone-based angiotensin II receptor antagonists with equivalent affinity for both the AT1 and AT2 subtypesEBI TBA
 134 Development of angiotensin II antagonists with equipotent affinity for human AT1 and AT2 receptor subtypes.EBI TBA
 54 A new class of balanced AT1/AT2 angiotensin II antagonists: quinazolinone AII antagonists with acylsulfonamide and sulfonylcarbamate acidic functionalitiesEBI TBA
 36 Quinazolinone Biphenyl Acylsulfonamides: A potent new class of angiotensin-II receptor antagonistsEBI TBA
 50 Potent imidazole angiotensinII antagonists: acyl sulfonamides and acyl sulfamides as tetrazole replacementsEBI TBA
 10 Evaluation of heterocyclic acid equivalents as tetrazole replacements in imidazopyridine-based nonpeptide angiotensin II receptor antagonistsEBI TBA
 8 Synthesis of new imidazo[1,2-b]pyridazine isosteres of potent imidazo[4,5-b]pyridine angiotensin II antagonistsEBI TBA
 22 Acidic phenols: a new class of potent nonpeptide angiotensin II receptor antagonistsEBI TBA
 24 Subtituted phenylthiophene benzoylsulfonamides with potent binding affinity to angiotensin II AT1 and AT2 receptorsEBI TBA
 42 Imidazo[4,5-b]pyridine-based AT1 / AT2 angiotensin II receptor antagonistsEBI TBA
 19 Triazolinones as nonpeptide angiotensin II antagonists. 2. discovery of a potent and orally active triazolinone acylsulfonamideEBI TBA
 10 Angiotensin II receptor antagonists containing a phenylpyridine element.EBI TBA
 45 Quinazolinones 2: QSAR and in vivo characterization of AT1 selective AII antagonistsEBI TBA
 23 Quinazolinones 1: design and synthesis of potent quinazolinone- containing AT1-selective angiotensin-II receptor antagonistsEBI TBA
 56 Synthesis and structure-activity relationships of a novel series of non-peptide AT2-selective angiotensin II receptor antagonistsEBI TBA
18599297 50 Selective angiotensin II AT2 receptor agonists: Benzamide structure-activity relationships.EBI Uppsala University
17825570 32 Selective angiotensin II AT(2) receptor agonists devoid of the imidazole ring system.EBI Uppsala University
17412584 26 Synthesis and biological activity of 2-alkylbenzimidazoles bearing a N-phenylpyrrole moiety as novel angiotensin II AT1 receptor antagonists.EBI China Pharmaceutical University
17064065 6 Further studies on imidazo[4,5-b]pyridine AT1 angiotensin II receptor antagonists. Effects of the transformation of the 4-phenylquinoline backbone into 4-phenylisoquinolinone or 1-phenylindene scaffolds.EBI Università di Siena
10579820 4 Specific nonpeptide photoprobes as tools for the structural study of the angiotensin II AT(1) receptor.EBI Laboratoires Fournier S.A.
9046346 1 Synthesis and structure-activity relationship of a new series of potent AT1 selective angiotensin II receptor antagonists: 5-(biphenyl-4-ylmethyl)pyrazoles.EBI J. Uriach & Cía, S.A.
8496939 100 Nonpeptide angiotensin II antagonists derived from 4H-1,2,4-triazoles and 3H-imidazo[1,2-b][1,2,4]triazoles.EBI Merck Research Laboratories
8355255 103 Triazolinones as nonpeptide angiotensin II antagonists. 1. Synthesis and evaluation of potent 2,4,5-trisubstituted triazolinones.EBI Merck Research Laboratories
8277506 58 Non-peptide angiotensin II receptor antagonists. 2. Design, synthesis, and biological activity of N-substituted (phenylamino)phenylacetic acids and acyl sulfonamides.EBI Merck Research Laboratories
8277505 58 Non-peptide angiotensin II receptor antagonists. 1. Design, synthesis, and biological activity of N-substituted indoles and dihydroindoles.EBI Merck Research Laboratories
8246245 26 (Dipropylphenoxy)phenylacetic acids: a new generation of nonpeptide angiotensin II receptor antagonists.EBI Merck Research Laboratories
8246227 57 Nonpeptide angiotensin II antagonists derived from 1H-pyrazole-5-carboxylates and 4-aryl-1H-imidazole-5-carboxylates.EBI Merck Research Laboratories
8230109 18 A potent, orally active, balanced affinity angiotensin II AT1 antagonist and AT2 binding inhibitor.EBI Merck Research Laboratories
8064808 202 Triazolinone biphenylsulfonamide derivatives as orally active angiotensin II antagonists with potent AT1 receptor affinity and enhanced AT2 affinity.EBI Merck Research Laboratories
7990105 16 A highly potent, orally active imidazo[4,5-b]pyridine biphenylacylsulfonamide (MK-996; L-159,282): a new AT1-selective angiotensin II receptor antagonist.EBI Merck Research Laboratories
7799397 86 Triazolinone biphenylsulfonamides as angiotensin II receptor antagonists with high affinity for both the AT1 and AT2 subtypes.EBI Merck Research Laboratories
7562905 258 Potent and orally active angiotensin II receptor antagonists with equal affinity for human AT1 and AT2 subtypes.EBI Merck Research Laboratories
2362273 1 Conformational restriction of angiotensin II: cyclic analogues having high potency.EBI G. D. Searle and Company
1433184 18 Discovery of a novel class of orally active, non-peptide angiotensin II antagonists.EBI Abbott Laboratories
15831442 46 Beneficial effects of a new 20-hydroxyeicosatetraenoic acid synthesis inhibitor, TS-011 [N-(3-chloro-4-morpholin-4-yl) phenyl-N'-hydroxyimido formamide], on hemorrhagic and ischemic stroke.BDB Taisho Pharmaceutical Co., Ltd
12721338 61 N-(4-tertiarybutylphenyl)-4-(3-chloropyridin-2-yl)tetrahydropyrazine -1(2H)-carbox-amide (BCTC), a novel, orally effective vanilloid receptor 1 antagonist with analgesic properties: I. in vitro characterization and pharmacokinetic properties.BDB Pudue Pharma Discovery Research
12570021 16 Binding of KRH-594, an antagonist of the angiotensin II type 1 receptor, to cloned human and rat angiotensin II receptors.BDB Shinshu University
11082453 77 ABT-702 (4-amino-5-(3-bromophenyl)-7-(6-morpholinopyridin-3-yl)pyrido[2, 3-d]pyrimidine), a novel orally effective adenosine kinase inhibitor with analgesic and anti-inflammatory properties: I. In vitro characterization and acute antinociceptive effects in the mouse.BDB Abbott Laboratories
8996185 121 Neurochemical characteristics of amisulpride, an atypical dopamine D2/D3 receptor antagonist with both presynaptic and limbic selectivity.BDB Synthélabo Recherche
7891350 9 Pharmacologic characterization of CI-996, a new angiotensin receptor antagonist.BDB Parke-Davis Pharmaceutical Research
7582507 14 RS 39604: a potent, selective and orally active 5-HT4 receptor antagonist.BDB Syntex Discovery Research