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276 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
28273563 59 Discovery of highly selective and potent monoamine oxidase B inhibitors: Contribution of additional phenyl rings introduced intoá2-aryl-1,3,4-oxadiazin-5(6H)-one.EBI Seoul National University
28186757 66 Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 2: Structure-Based Drug Design and Structure-Activity Relationship.EBI European Institute of Oncology
28186755 85 Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 1: High-Throughput Screening and Preliminary Exploration.EBI European Institute of Oncology
28131710 22 DL-3-n-butylphthalide-Edaravone hybrids as novel dual inhibitors of amyloid-▀ aggregation and monoamine oxidases with high antioxidant potency for Alzheimer's therapy.EBI Sichuan University
27951485 59 Aurone Mannich base derivatives as promising multifunctional agents with acetylcholinesterase inhibition, anti-▀-amyloid aggragation and neuroprotective properties for the treatment of Alzheimer's disease.EBI Sichuan University
28188065 9 Selective inhibition of monoamine oxidase A by purpurin, an anthraquinone.EBI Sunchon National University
28107736 53 Crystal structures, binding interactions, and ADME evaluation of brain penetrant N-substituted indazole-5-carboxamides as subnanomolar, selective monoamine oxidase B and dual MAO-A/B inhibitors.EBI NTZ Lab Ltd
28237559 65 Multifunctional thioxanthone derivatives with acetylcholinesterase, monoamine oxidases and▀-amyloid aggregation inhibitory activities as potential agents against Alzheimer's disease.EBI Sichuan University
28011206 36 Design, synthesis and biological evaluation of 4'-aminochalcone-rivastigmine hybrids as multifunctional agents for the treatment of Alzheimer's disease.EBI Sichuan University
27923535 39 Multitarget drug design strategy against Alzheimer's disease: Homoisoflavonoid Mannich base derivatives serve as acetylcholinesterase and monoamine oxidase B dual inhibitors with multifunctional properties.EBI Sichuan University
27908752 55 N-Propargylpiperidines with naphthalene-2-carboxamide or naphthalene-2-sulfonamide moieties: Potential multifunctional anti-Alzheimer's agents.EBI University of Ljubljana
27692996 84 Neuroprotective effects of benzyloxy substituted small molecule monoamine oxidase B inhibitors in Parkinson's disease.EBI China Pharmaceutical University
26471320 50 Donepezil-like multifunctional agents: Design, synthesis, molecular modeling and biological evaluation.EBI Okayama University
27267007 58 New cinnamic - N-benzylpiperidine and cinnamic - N,N-dibenzyl(N-methyl)amine hybrids as Alzheimer-directed multitarget drugs with antioxidant, cholinergic, neuroprotective and neurogenic properties.EBI Instituto de Qu£mica M£dica
27578245 46 2-Benzylidene-1-indanone derivatives as inhibitors of monoamine oxidase.EBI North-West University
27135371 26 (E)-3-Heteroarylidenechroman-4-ones as potent and selective monoamine oxidase-B inhibitors.EBI Universit£ di Roma
27079124 22 Synthesis and evaluation of 4-hydroxyl aurone derivatives as multifunctional agents for the treatment of Alzheimer's disease.EBI Sichuan University
26710088 248 Recent Progress in Histone Demethylase Inhibitors.EBI University of Oxford
26819666 26 Monoamine Oxidase Inhibitory Activity of Novel Pyrazoline Analogues: Curcumin Based Design and Synthesis.EBI Birla Institute of Technology
26702542 59 Discovery of a Novel Inhibitor of Histone Lysine-Specific Demethylase 1A (KDM1A/LSD1) as Orally Active Antitumor Agent.EBI European Institute of Oncology
26974383 11 Design and synthesis of novel chalcones as potent selective monoamine oxidase-B inhibitors.EBI Qatar University
26700437 32 Identification of SNAIL1 Peptide-Based Irreversible Lysine-Specific Demethylase 1-Selective Inactivators.EBI Kyoto Prefectural University of Medicine
26964672 26 Novel tricyclic pyrazolo[1,5-d][1,4]benzoxazepin-5(6H)-one: Design, synthesis, model and use as hMAO-B inhibitors.EBI Anhui Medical University
26717204 17 Drug design, synthesis, inávitro and in silico evaluation of selective monoaminoxidase B inhibitors based on 3-acetyl-2-dichlorophenyl-5-aryl-2,3-dihydro-1,3,4-oxadiazole chemical scaffold.EBI Universit£ degli Studi di Cagliari
26917219 63 Design, synthesis and biological evaluation of novel donepezil-coumarin hybrids as multi-target agents for the treatment of Alzheimer's disease.EBI China Pharmaceutical University
26821818 25 Inhibition of monoamine oxidase by benzoxathiolone analogues.EBI North-West University
26652247 60 3-(Piperidin-4-ylmethoxy)pyridine Containing Compounds Are Potent Inhibitors of Lysine Specific Demethylase 1.EBI Baylor College of Medicine
26432037 14 Monoamine oxidase inhibitory activities of heterocyclic chalcones.EBI North-West University
26352677 44 Novel 2H-chromen-2-one derivatives of resveratrol: Design, synthesis, modeling and use as human monoamine oxidase inhibitors.EBI Hefei University of Technology
26086931 38 Strategies for the Discovery of Target-Specific or Isoform-Selective Modulators.EBI Shandong University
26337020 69 Synthesis of a series of unsaturated ketone derivatives as selective and reversible monoamine oxidase inhibitors.EBI Korea Institute of Science and Technology
26278660 90 Evaluation of Homobivalent Carbolines as Designed Multiple Ligands for the Treatment of Neurodegenerative Disorders.EBI University of Jena
25915162 12 New Frontiers in Selective Human MAO-B Inhibitors.EBI Sapienza University of Rome
25934229 21 Synthesis and evaluation of selegiline derivatives as monoamine oxidase inhibitor, antioxidant and metal chelator against Alzheimer's disease.EBI Sun Yat-sen University
26107513 172 Structure-Based Design and Optimization of Multitarget-Directed 2H-Chromen-2-one Derivatives as Potent Inhibitors of Monoamine Oxidase B and Cholinesterases.EBI Universit£ degli Studi di Bari"Aldo Moro"
25699146 13 Pure Diastereomers of a Tranylcypromine-Based LSD1 Inhibitor: Enzyme Selectivity and In-Cell Studies.EBI Sapienza University of Rome
25812965 80 Multi-target tacrine-coumarin hybrids: cholinesterase and monoamine oxidase B inhibition properties against Alzheimer's disease.EBI China Pharmaceutical University
25768700 30 Pure enantiomers of benzoylamino-tranylcypromine: LSD1 inhibition, gene modulation in human leukemia cells and effects on clonogenic potential of murine promyelocytic blasts.EBI Sapienza University of Rome
25627172 150 Novel arylalkenylpropargylamines as neuroprotective, potent, and selective monoamine oxidase B inhibitors for the treatment of Parkinson's disease.EBI A* STAR
25610955 53 Design, synthesis, and structure-activity relationship of novel LSD1 inhibitors based on pyrimidine-thiourea hybrids as potent, orally active antitumor agents.EBI Zhengzhou University
25418133 51 N-Methyl-N-((1-methyl-5-(3-(1-(2-methylbenzyl)piperidin-4-yl)propoxy)-1H-indol-2-yl)methyl)prop-2-yn-1-amine, a new cholinesterase and monoamine oxidase dual inhibitor.EBI Laboratorio de Quimica Medica (IQOG, CSIC)
25857942 30 The synthesis and evaluation of sesamol and benzodioxane derivatives as inhibitors of monoamine oxidase.EBI North-West University
25827526 33 Histone H3 peptide based LSD1-selective inhibitors.EBI Waseda University
25725609 18 Structure-activity study for (bis)ureidopropyl- and (bis)thioureidopropyldiamine LSD1 inhibitors with 3-5-3 and 3-6-3 carbon backbone architectures.EBI John Hopkins University
25600407 26 Reversible and irreversible small molecule inhibitors of monoamine oxidase B (MAO-B) investigated by biophysical techniques.EBI Dart Neuroscience LLC
25701250 32 Inhibition of monoamine oxidase by indole-5,6-dicarbonitrile derivatives.EBI Yaroslavl State Technical University
25542589 23 Multifunctional coumarin derivatives: monoamine oxidase B (MAO-B) inhibition, anti-▀-amyloid (A▀) aggregation and metal chelation properties against Alzheimer's disease.EBI China Pharmaceutical University
25541201 55 Design and synthesis of novel 2-pyrazoline-1-ethanone derivatives as selective MAO inhibitors.EBI Anhui Medical University
24986657 56 Synthesis of some novel hydrazone and 2-pyrazoline derivatives: monoamine oxidase inhibitory activities and docking studies.EBI Ministry of Health of Turkey
24955776 166 Indazole- and indole-5-carboxamides: selective and reversible monoamine oxidase B inhibitors with subnanomolar potency.EBI University of Bonn
25532905 10 Potent and selective MAO-B inhibitory activity: amino- versus nitro-3-arylcoumarin derivatives.EBI Universidad de Santiago de Compostela
25488845 4 Radiosynthesis and ex vivo evaluation of [(18)F]-(S)-3-(6-(3-fluoropropoxy)benzo[d]isoxazol-3-yl)-5-(methoxymethyl)oxazolidin-2-one for imaging MAO-B with PET.EBI University of Toronto
25173853 50 Synthesis, biological activity and mechanistic insights of 1-substituted cyclopropylamine derivatives: a novel class of irreversible inhibitors of histone demethylase KDM1A.EBI European Institute of Oncology
24904963 18 New insights into the biological properties of Crocus sativus L.: chemical modifications, human monoamine oxidases inhibition and molecular modeling studies.EBI Sapienza University of Rome
24856304 25 New coumarin derivatives: design, synthesis and use as inhibitors of hMAO.EBI Anhui Medical University
24794105 38 a-Tetralone derivatives as inhibitors of monoamine oxidase.EBI North-West University
24793878 25 New 2H-chromene-3-carboxamide derivatives: design, synthesis and use as inhibitors of hMAO.EBI Anhui Medical University
24746464 29 Identification of the stereochemical requirements in the 4-aryl-2-cycloalkylidenhydrazinylthiazole scaffold for the design of selective human monoamine oxidase B inhibitors.EBI Sapienza University of Rome
24187998 96 Design, synthesis, and biological evaluation of Erythrina alkaloid analogues as neuronal nicotinic acetylcholine receptor antagonists.EBI University of Copenhagen
23454517 56 A novel series of tacrine-selegiline hybrids with cholinesterase and monoamine oxidase inhibition activities for the treatment of Alzheimer's disease.EBI Sun Yat-sen University
23211968 7 Synthesis and biological evaluation of novel propargyl amines as potential fluorine-18 labeled radioligands for detection of MAO-B activity.EBI Karolinska Institutet
23207410 42 1,5-Diphenylpenta-2,4-dien-1-ones as potent and selective monoamine oxidase-B inhibitors.EBI Sapienza University of Rome
23337801 24 Synthesis and SAR study of new thiazole derivatives as vascular adhesion protein-1 (VAP-1) inhibitors for the treatment of diabetic macular edema.EBI Astellas Pharma Inc
23281824 118 Synthesis of (E)-8-(3-chlorostyryl)caffeine analogues leading to 9-deazaxanthine derivatives as dual A(2A) antagonists/MAO-B inhibitors.EBI Universit£ degli Studi di Parma
15203146 30 Inhibition of monoamine oxidases by coumarin-3-acyl derivatives: biological activity and computational study.EBI Sapienza University of Rome
12443774 12 Natural and synthetic geiparvarins are strong and selective MAO-B inhibitors. Synthesis and SAR studies.EBI University of Bari
22705191 45 Inhibition of monoamine oxidase by 8-phenoxymethylcaffeine derivatives.EBI North-West University
20934874 16 Synthesis and molecular modelling studies of prenylated pyrazolines as MAO-B inhibitors.EBI Sapienza University of Rome
17034132 122 Impact of species-dependent differences on screening, design, and development of MAO B inhibitors.EBI University of Geneva
23122934 44 Inhibition of monoamine oxidase by 8-[(phenylethyl)sulfanyl]caffeine analogues.EBI North-West University
23122857 49 Sulfanylphthalonitrile analogues as selective and potent inhibitors of monoamine oxidase B.EBI North-West University
23102654 20 Inhibition of monoamine oxidase by derivatives of piperine, an alkaloid from the pepper plant Piper nigrum, for possible use in Parkinson's disease.EBI Northeast Ohio Medical University
22978824 17 Multitarget-directed benzylideneindanone derivatives: anti-ß-amyloid (Aß) aggregation, antioxidant, metal chelation, and monoamine oxidase B (MAO-B) inhibition properties against Alzheimer's disease.EBI Sun Yat-sen University
23010267 23 Novel sulfanylphthalimide analogues as highly potent inhibitors of monoamine oxidase B.EBI North-West University
23153812 68 Recent advances in the development of selective human MAO-B inhibitors: (hetero)arylidene-(4-substituted-thiazol-2-yl)hydrazines.EBI Sapienza University of Rome
22850212 30 Selected chromone derivatives as inhibitors of monoamine oxidase.EBI North-West University
22781190 102 Synthesis and evaluation of aplysinopsin analogs as inhibitors of human monoamine oxidase A and B.EBI University of Mississippi
22595173 68 The discovery and development of selective 3-fluoro-4-aryloxyallylamine inhibitors of the amine oxidase activity of semicarbazide-sensitive amine oxidase/vascular adhesion protein-1 (SSAO/VAP-1).EBI Pharmaxis Ltd.
22282722 10 Molecular Insights into Human Monoamine Oxidase B Inhibition by the Glitazone Anti-Diabetes Drugs.EBI TBA
22436387 4 Synthesis and evaluation of [¹8F]fluororasagiline, a novel positron emission tomography (PET) radioligand for monoamine oxidase B (MAO-B).EBI Karolinska Institutet
21742494 44 Structure-activity relationship and docking studies of thiazolidinedione-type compounds with monoamine oxidase B.EBI Northeastern Ohio Universities Colleges of Medicine and Pharmacy
21726069 98 Tryptophan 2,3-dioxygenase (TDO) inhibitors. 3-(2-(pyridyl)ethenyl)indoles as potential anticancer immunomodulators.EBI University of Namur
21175212 3 Interactions of monoamine oxidases with the antiepileptic drug zonisamide: specificity of inhibition and structure of the human monoamine oxidase B complex.EBI University of Pavia
20875743 90 Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: design, synthesis, and structure-activity relaEBI Pfizer Inc
20708306 68 Synthesis of new series of quinoxaline based MAO-inhibitors and docking studies.EBI Alexandria University
20579890 111 Synthesis, semipreparative HPLC separation, biological evaluation, and 3D-QSAR of hydrazothiazole derivatives as human monoamine oxidase B inhibitors.EBI Sapienza University of Rome
20650633 12 Identification of novel monoamine oxidase B inhibitors by structure-based virtual screening.EBI Northeastern Ohio Universities
20123154 48 2-Arylthiomorpholine derivatives as potent and selective monoamine oxidase B inhibitors.EBI University of Chile
18272363 7 Potent, nonpeptide inhibitors of human mast cell tryptase. Synthesis and biological evaluation of novel spirocyclic piperidine amide derivatives.EBI Johnson & Johnson Pharmaceutical Research & Development
18181565 71 Multi-target-directed ligands to combat neurodegenerative diseases.EBI University of Bologna
16570912 24 Design, synthesis, and biological evaluation of semicarbazide-sensitive amine oxidase (SSAO) inhibitors with anti-inflammatory activity.EBI La Jolla Pharmaceutical Company
15537343 4 Fluorinated phenylcyclopropylamines. 2. Effects of aromatic ring substitution and of absolute configuration on inhibition of microbial tyramine oxidase.EBI Universit£t M£nster
15056004 36 Synthesis and selective inhibitory activity of 1-acetyl-3,5-diphenyl-4,5-dihydro-(1H)-pyrazole derivatives against monoamine oxidase.EBI Sapienza University of Rome
15027872 7 Fluorinated phenylcyclopropylamines. 1. Synthesis and effect of fluorine substitution at the cyclopropane ring on inhibition of microbial tyramine oxidase.EBI National Institute of Diabetes and Digestive and Kidney Diseases
2296014 42 Inhibition of monoamine oxidases A and B by simple isoquinoline alkaloids: racemic and optically active 1,2,3,4-tetrahydro-, 3,4-dihydro-, and fully aromatic isoquinolines.EBI University of Texas
22264472 30 Inhibition of human monoamine oxidase A and B by 5-phenoxy 8-aminoquinoline analogs.EBI University of Mississippi
22309913 30 Inhibition of monoamine oxidase by selected C6-substituted chromone derivatives.EBI North-West University
22225638 18 A scaffold hopping approach to identify novel monoamine oxidase B inhibitors.EBI Northeast Ohio Medical University
22078410 31 Time-dependent slowly-reversible inhibition of monoamine oxidase A by N-substituted 1,2,3,6-tetrahydropyridines.EBI West Virginia University
21955276 60 Lysine demethylases inhibitors.EBI Kyoto Prefectural University of Medicine
22222137 13 Synthesis and biological assessment of novel 2-thiazolylhydrazones and computational analysis of their recognition by monoamine oxidase B.EBI Universit£ degli Studi Magna Gr£cia di Catanzaro
22137786 9 Hydroxycoumarins as selective MAO-B inhibitors.EBI Universit£ degli Studi di Cagliari
22071524 7 Molecular insights into human monoamine oxidase (MAO) inhibition by 1,4-naphthoquinone: evidences for menadione (vitamin K3) acting as a competitive and reversible inhibitor of MAO.EBI Federal University of Rio de Janeiro
22055712 33 Thio- and aminocaffeine analogues as inhibitors of human monoamine oxidase.EBI North-West University
22018876 4 Synthesis and inhibition study of monoamine oxidase, indoleamine 2,3-dioxygenase and tryptophan 2,3-dioxygenase by 3,8-substituted 5H-indeno[1,2-c]pyridazin-5-one derivatives.EBI Facult£s Universitaires Notre-Dame de Paix
22005185 25 2D MI-DRAGON: a new predictor for protein-ligands interactions and theoretic-experimental studies of US FDA drug-target network, oxoisoaporphine inhibitors for MAO-A and human parasite proteins.EBI University of Santiago de Compostela
21923198 6 Synthesis of three novel fluorine-18 labeled analogues of L-deprenyl for positron emission tomography (PET) studies of monoamine oxidase B (MAO-B).EBI Karolinska Institutet
21923181 28 Synthesis and study of a series of 3-arylcoumarins as potent and selective monoamine oxidase B inhibitors.EBI University of Santiago de Compostela
21899930 37 Monoamine oxidase inhibition by selected anilide derivatives.EBI North-West University
21872365 54 Synthesis and selective human monoamine oxidase inhibition of 3-carbonyl, 3-acyl, and 3-carboxyhydrazido coumarin derivatives.EBI Sapienza University of Rome
21777011 15 3-Acetyl-2,5-diaryl-2,3-dihydro-1,3,4-oxadiazoles: a new scaffold for the selective inhibition of monoamine oxidase B.EBI University of Cagliari
21778064 40 Inhibition of monoamine oxidase by C5-substituted phthalimide analogues.EBI North-West University
21696156 23 Chromone, a privileged scaffold for the development of monoamine oxidase inhibitors.EBI Universidade do Porto
21621312 58 8-Aryl- and alkyloxycaffeine analogues as inhibitors of monoamine oxidase.EBI North-West University
21684743 12 MAO inhibitory activity modulation: 3-Phenylcoumarins versus 3-benzoylcoumarins.EBI Universidad de Santiago de Compostela
21680183 48 Pyrazoline based MAO inhibitors: synthesis, biological evaluation and SAR studies.EBI Birla Institute of Technology
19423346 8 A new series of 3-phenylcoumarins as potent and selective MAO-B inhibitors.EBI Facultad de Farmacia
21405131 39 Homoisoflavonoids: natural scaffolds with potent and selective monoamine oxidase-B inhibition properties.EBI Sapienza University of Rome
21377879 44 Development of selective and reversible pyrazoline based MAO-B inhibitors: virtual screening, synthesis and biological evaluation.EBI Birla Institute of Technology
21316817 14 Synthesis, human monoamine oxidase inhibitory activity and molecular docking studies of 3-heteroarylcoumarin derivatives.EBI Universita degli Studi di Cagliari
21134756 90 Inhibition of monoamine oxidase by selected C5- and C6-substituted isatin analogues.EBI North-West University
21194943 9 Chromone 3-phenylcarboxamides as potent and selective MAO-B inhibitors.EBI Universidade do Porto
21183355 18 Synthesis and evaluation ofß-carboline derivatives as potential monoamine oxidase inhibitors.EBI Facult£s Universitaires Notre-Dame de la Paix
20843688 8 'Click' assembly of selective inhibitors for MAO-A.EBI Zhejiang University
20702005 17 Synthesis of new 3-aryl-4,5-dihydropyrazole-1-carbothioamide derivatives. An investigation on their ability to inhibit monoamine oxidase.EBI Dipartimento Farmaco Chimico Tecnologico
20674099 48 Inhibition of monoamine oxidase by indole and benzofuran derivatives.EBI North-West University
20715818 78 Synthesis, stereochemical separation, and biological evaluation of selective inhibitors of human MAO-B: 1-(4-arylthiazol-2-yl)-2-(3-methylcyclohexylidene)hydrazines.EBI Sapienza University of Rome
20659799 10 New halogenated 3-phenylcoumarins as potent and selective MAO-B inhibitors.EBI Universidad de Santiago de Compostela
20615716 55 Investigations on the 2-thiazolylhydrazyne scaffold: synthesis and molecular modeling of selective human monoamine oxidase inhibitors.EBI Sapienza University of Rome
20382016 8 Chromone-2- and -3-carboxylic acids inhibit differently monoamine oxidases A and B.EBI Universit£ Magna Graecia di Catanzaro
19926363 29 Synthesis and inhibitory activity against human monoamine oxidase of N1-thiocarbamoyl-3,5-di(hetero)aryl-4,5-dihydro-(1H)-pyrazole derivatives.EBI Universit£ di Roma
20045650 56 A new series of flavones, thioflavones, and flavanones as selective monoamine oxidase-B inhibitors.EBI Sapienza University of Rome
20093036 28 Inhibition of monoamine oxidase by 8-benzyloxycaffeine analogues.EBI North-West University
19628387 6 Synthesis and evaluation of 6-methyl-3-phenylcoumarins as potent and selective MAO-B inhibitors.EBI Universidad de Santiago de Compostela
19321235 22 Knowledge based identification of MAO-B selective inhibitors using pharmacophore and structure based virtual screening models.EBI GVK Biosciences Pvt. Ltd
 52 Imino 1,2,3,4-tetrahydrocyclopent[b]indole carbamates as dual inhibitors of acetylcholinesterase and monoamine oxidaseEBI TBA
19342233 12 Inhibition of monoamine oxidase by (E)-styrylisatin analogues.EBI North-West University
19064321 37 Ultrasound promoted synthesis of 2-imidazolines in water: a greener approach toward monoamine oxidase inhibitors.EBI Universidade Federal de Santa Maria
19053775 4 Structural and mechanistic studies of mofegiline inhibition of recombinant human monoamine oxidase B.EBI Emory University
18834112 52 Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.EBI University of Santiago de Compostela
18723354 12 Dual inhibition of monoamine oxidase B and antagonism of the adenosine A(2A) receptor by (E,E)-8-(4-phenylbutadien-1-yl)caffeine analogues.EBI North-West University
18666768 39 Synthesis, stereochemical identification, and selective inhibitory activity against human monoamine oxidase-B of 2-methylcyclohexylidene-(4-arylthiazol-2-yl)hydrazones.EBI Sapienza University of Rome
18640844 38 Fluorinated phenylcyclopropylamines. Part 5: Effects of electron-withdrawing or -donating aryl substituents on the inhibition of monoamine oxidases A and B by 2-aryl-2-fluoro-cyclopropylamines.EBI Universität Münster
17521909 15 Human and rat monoamine oxidase-A are differentially inhibited by (S)-4-alkylthioamphetamine derivatives: insights from molecular modeling studies.EBI University of Santiago de Chile
16137882 10 Docking studies on monoamine oxidase-B inhibitors: estimation of inhibition constants (K(i)) of a series of experimentally tested compounds.EBI Kadir Has University
15974574 56 Design, synthesis, and biological activities of pyrrolylethanoneamine derivatives, a novel class of monoamine oxidases inhibitors.EBI Sapienza University of Rome
12540239 3 Indanylidenes. 1. Design and synthesis of (E)-2-(4,6-difluoro-1-indanylidene)acetamide, a potent, centrally acting muscle relaxant with antiinflammatory and analgesic activity.EBI GlaxoSmithKline
12467619 12 Rational approaches towards reversible inhibition of type B monoamine oxidase. Design and evaluation of a novel 5H-Indeno[1,2-c]pyridazin-5-one derivative.EBI Facultés Universitaires Notre-Dame de la Paix
12443791 14 Inhibition of amine oxidases activity by 1-acetyl-3,5-diphenyl-4,5-dihydro-(1H)-pyrazole derivatives.EBI Sapienza University of Rome
27020523 73 An evaluation of synthetic indole derivatives as inhibitors of monoamine oxidase.EBI Yaroslavl State Technical University
26536532 19 Synthesis and biological evaluation of novel 5-(hydroxamic acid)methyl oxazolidinone derivatives.EBI Kuwait University
25580204 10 3,5-Diamino-1,2,4-triazoles as a novel scaffold for potent, reversible LSD1 (KDM1A) inhibitors.EBI Medical University of South Carolina
24560738 64 Alkynyl-coumarinyl ethers as MAO-B inhibitors.EBI University of Bonn
24325601 74 Pan-histone demethylase inhibitors simultaneously targeting Jumonji C and lysine-specific demethylases display high anticancer activities.EBI Sapienza University of Rome
24169316 46 Chromenylchalcones with inhibitory effects on monoamine oxidase B.EBI Konkuk University
24139167 419 1,3-Dialkyl-substituted tetrahydropyrimido[1,2-f]purine-2,4-diones as multiple target drugs for the potential treatment of neurodegenerative diseases.EBI University of Bonn
24140951 19 Novel polyamine analogues: from substrates towards potential inhibitors of monoamine oxidases.EBI University of Padova
24012376 5 Development of a novel fluorine-18 labeled deuterated fluororasagiline ([(18)F]fluororasagiline-D2) radioligand for PET studies of monoamino oxidase B (MAO-B).EBI Karolinska Institutet
24099995 21 Monoamine oxidase inhibitory activity of 3,5-biaryl-4,5-dihydro-1H-pyrazole-1-carboxylate derivatives.EBI Birla Institute of Technology
24012182 28 Inhibition of monoamine oxidase by 3,4-dihydro-2(1H)-quinolinone derivatives.EBI North-West University
23927971 51 Design, synthesis, and in vitro hMAO-B inhibitory evaluation of some 1-methyl-3,5-diphenyl-4,5-dihydro-1H-pyrazoles.EBI Universit£ La Sapienza
23860591 38 Selected furanochalcones as inhibitors of monoamine oxidase.EBI North-West University
23807114 12 Exploring 4-substituted-2-thiazolylhydrazones from 2-, 3-, and 4-acetylpyridine as selective and reversible hMAO-B inhibitors.EBI Sapienza University of Rome
23374869 49 Inhibition of monoamine oxidase by phthalide analogues.EBI North-West University
23631427 212 Dual targeting of adenosine A(2A) receptors and monoamine oxidase B by 4H-3,1-benzothiazin-4-ones.EBI University of Bonn
23517722 13 A comprehensive review on synthesis and designing aspects of coumarin derivatives as monoamine oxidase inhibitors for depression and Alzheimer's disease.EBI R.C. Patel Institute of Pharmaceutical Education and Research
23474901 12 Novel (coumarin-3-yl)carbamates as selective MAO-B inhibitors: synthesis, in vitro and in vivo assays, theoretical evaluation of ADME properties and docking study.EBI University of Santiago de Compostela
23207409 24 Combining QSAR classification models for predictive modeling of human monoamine oxidase inhibitors.EBI Universidade do Porto
30096650 102 Donepezil-butylated hydroxytoluene (BHT) hybrids as Anti-Alzheimer's disease agents with cholinergic, antioxidant, and neuroprotective properties.EBI China Pharmaceutical University
30025348 149 Neurogenic and neuroprotective donepezil-flavonoid hybrids with sigma-1 affinity and inhibition of key enzymes in Alzheimer's disease.EBI Consejo Superior de Investigaciones Cient�ficas (IQM-CSIC)
30245401 61 Multi-target-directed ligands for Alzheimer's disease: Discovery of chromone-based monoamine oxidase/cholinesterase inhibitors.EBI University of Porto
30243151 23 Donepezil-based multi-functional cholinesterase inhibitors for treatment of Alzheimer's disease.EBI China Pharmaceutical University
29247860 80 Structure-activity studies on N-Substituted tranylcypromine derivatives lead to selective inhibitors of lysine specific demethylase 1 (LSD1) and potent inducers of leukemic cell differentiation.EBI University of Freiburg
30153955 20 Optimization of 5-arylidene barbiturates as potent, selective, reversible LSD1 inhibitors for the treatment of acute promyelocytic leukemia.EBI Fudan University
30016860 58 Development of Novel Monoamine Oxidase-B (MAO-B) Inhibitors with Reduced Blood-Brain Barrier Permeability for the Potential Management of Noncentral Nervous System (CNS) Diseases.EBI The University of British Columbia
29500132 59 Multifunctional 5,6-dimethoxybenzo[d]isothiazol-3(2H)-one-N-alkylbenzylamine derivatives with acetylcholinesterase, monoamine oxidases and ?-amyloid aggregation inhibitory activities as potential agents against Alzheimer's disease.EBI Sichuan University
29331452 9 Design, synthesis and evaluation of ?-turn mimetics as LSD1-selective inhibitors.EBI Kyoto Prefectural University of Medicine
3260955 14 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine analogues. Inactivation of monoamine oxidase by conformationally rigid analogues of N,N-dimethylcinnamylamine.EBI Northwestern University
29477889 36 Novel indanone derivatives as MAO B/HEBI Heinrich Heine University Duesseldorf
29459279 10 Cyclic peptide inhibitors of lysine-specific demethylase 1 with improved potency identified by alanine scanning mutagenesis.EBI Medical University of South Carolina
28797883 56 Design, synthesis and biological evaluation of novel coumarin-N-benzyl pyridinium hybrids as multi-target agents for the treatment of Alzheimer's disease.EBI Shanghai University of Traditional Chinese Medicine
28797881 20 Synthesis and structure-activity relationship study of novel 3-heteroarylcoumarins based on pyridazine scaffold as selective MAO-B inhibitors.EBI Universidade de Vigo
28728104 52 Design, synthesis and evaluation of coumarin-pargyline hybrids as novel dual inhibitors of monoamine oxidases and amyloid-? aggregation for the treatment of Alzheimer's disease.EBI Shenyang Pharmaceutical University
29409707 6 Design, synthesis and evaluation of 4'-OH-flurbiprofen-chalcone hybrids as potential multifunctional agents for Alzheimer's disease treatment.EBI Sichuan University
29395970 18 Selective inhibition of monoamine oxidase A by hispidol.EBI Sunchon National University
29648817 7 Tight-Binding Inhibition of Human Monoamine Oxidase B by Chromone Analogs: A Kinetic, Crystallographic, and Biological Analysis.EBI University of Porto
29198865 9 Histone H3 peptides incorporating modified lysine residues as lysine-specific demethylase 1 inhibitors.EBI Waseda University
29198609 96 Synthesis and evaluation of biaryl derivatives for structural characterization of selective monoamine oxidase B inhibitors toward Parkinson's disease therapy.EBI Yonsei University
28988627 22 Design, synthesis, and evaluation of salicyladimine derivatives as multitarget-directed ligands against Alzheimer's disease.EBI Shenyang Pharmaceutical University
28082069 41 Synthesis and evaluation of frentizole-based indolyl thiourea analogues as MAO/ABAD inhibitors for Alzheimer's disease treatment.EBI Charles University in Prague
29339253 55 Design, synthesis and bioevalucation of novel 2,3-dihydro-1H-inden-1-amine derivatives as potent and selective human monoamine oxidase B inhibitors based on rasagiline.EBI Hefei University of Technology
29248751 36 Design, synthesis and biological assessment of new thiazolylhydrazine derivatives as selective and reversible hMAO-A inhibitors.EBI Anadolu University
29172081 68 Discovery of novel propargylamine-modified 4-aminoalkyl imidazole substituted pyrimidinylthiourea derivatives as multifunctional agents for the treatment of Alzheimer's disease.EBI East China University of Science and Technology
29126727 75 Design, synthesis and biochemical evaluation of novel multi-target inhibitors as potential anti-Parkinson agents.EBI "G. D'Annunzio" University of Chieti-Pescara
29969030 24 Contilisant, a Tetratarget Small Molecule for Alzheimer's Disease Therapy Combining Cholinesterase, Monoamine Oxidase Inhibition, and H3R Antagonism with S1R Agonism Profile.EBI IQOG, CSIC
29031059 61 Tying up tranylcypromine: Novel selective histone lysine specific demethylase 1 (LSD1) inhibitors.EBI East China Normal University
28987602 38 Design and synthesis of tranylcypromine derivatives as novel LSD1/HDACs dual inhibitors for cancer treatment.EBI Xinxiang Medical University
30017112 36 Developing hybrid molecule therapeutics for diverse enzyme inhibitory action: Active role of coumarin-based structural leads in drug discovery.EBI Abbottabad University of Science and Technology
29925480 26 Selective inhibition of monoamine oxidase A by chelerythrine, an isoquinoline alkaloid.EBI Sunchon National University
30279044 16 Synthesis and evaluation of 2-substituted 4(3H)-quinazolinone thioether derivatives as monoamine oxidase inhibitors.EBI North-West University
29792714 32 Docking Screens for Dual Inhibitors of Disparate Drug Targets for Parkinson's Disease.EBI Uppsala University
28549891 50 Synthesis and pharmacological evaluation of novel chromone derivatives as balanced multifunctional agents against Alzheimer's disease.EBI China Pharmaceutical University
28456030 20 The evaluation of 1,4-benzoquinones as inhibitors of human monoamine oxidase.EBI North-West University
29033233 56 Design, synthesis and biological evaluation of 2-acetyl-5-O-(amino-alkyl)phenol derivatives as multifunctional agents for the treatment of Alzheimer's disease.EBI Nanyang Normal University
29033232 164 Design, synthesis and biological evaluation of phthalimide-alkylamine derivatives as balanced multifunctional cholinesterase and monoamine oxidase-B inhibitors for the treatment of Alzheimer's disease.EBI Nanyang Normal University
28927796 42 Development and evaluation of 4-(pyrrolidin-3-yl)benzonitrile derivatives as inhibitors of lysine specific demethylase 1.EBI University of Manchester
28368606 5 Anisucoumaramide, a Bioactive Coumarin from Clausena anisum-olens.EBI Yunnan University
27855360 23 Benzyloxynitrostyrene analogues - A novel class of selective and highly potent inhibitors of monoamine oxidase B.EBI North-West University
27754693 16 Isolation of Acacetin from Calea urticifolia with Inhibitory Properties against Human Monoamine Oxidase-A and -B.EBI Temple University
27744252 102 Synthesis and evaluation of 7-substituted coumarin derivatives as multimodal monoamine oxidase-B and cholinesterase inhibitors for the treatment of Alzheimer's disease.EBI University of the Western Cape
28753307 35 Coumarin versus Chromone Monoamine Oxidase B Inhibitors: Quo Vadis?EBI University of Porto
28301816 22 MAO enzymes inhibitory activity of new benzimidazole derivatives including hydrazone and propargyl side chains.EBI Anadolu University
28487125 174 Design, synthesis and biological evaluation of 3,4-dihydro-2(1H)-quinoline-O-alkylamine derivatives as new multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer's disease.EBI Nanyang Normal University
29316397 47 Discovery of Potent and Orally Bioavailable Dihydropyrazole GPR40 Agonists.EBI Bristol-Myers Squibb Co.
28537720 5 Chromone as a Privileged Scaffold in Drug Discovery: Recent Advances.EBI University of Porto
21985377 42 Synthesis and biological evaluation of novel N, N'-disubstituted urea and thiourea derivatives as potential anti-melanoma agents.BDB Nanjing University
21815772 22 Inhibition of human carbonic anhydrase isozymes I, II and VI with a series of bisphenol, methoxy and bromophenol compounds.BDB Artvin Coruh University
20030512 1 New antihyperglycemic, alpha-glucosidase inhibitory, and cytotoxic derivatives of benzimidazoles.BDB Indian Institute of Chemical Technology
28525735 2 Structure-based rational design of self-inhibitory peptides to disrupt the intermolecular interaction between the troponin subunits C and I in neuropathic pain.BDB The Affiliated Hospital of Qingdao University
28481076 7 Heme Proximal Hydrogen Bonding between His170 and Asp132 Plays an Essential Role in the Heme Degradation Reaction of HutZ from Vibrio cholerae.BDB Hokkaido University
28387506 3 Interaction of Azole-Based Environmental Pollutants with the Coelomic Hemoglobin from Amphitrite ornata: A Molecular Basis for Toxicity.BDB North Carolina State University
14500740 13 Differential activation of formyl peptide receptor signaling by peptide ligands.BDB Pohang University of Science and Technology
11093776 5 Correlation of the apparent affinities and efficacies of gamma-aminobutyric acid(C) receptor agonists.BDB University of Alabama at Birmingham
8813598 34 Affinity of various ligands for GABAA receptors containing alpha 4 beta 3 gamma 2, alpha 4 gamma 2, or alpha 1 beta 3 gamma 2 subunits.BDB University Clinic for Psychiatry
8788493 64 Novel discriminatory ligands for 5-HT2B receptors.BDB SmithKline Beecham Pharmaceuticals Ltd
3014519 39 Design of potent, orally effective, nonpeptidal antagonists of the peptide hormone cholecystokinin.BDB Merck Sharp & Dohme Research Laboratories
19113826 12 Rigid duplex alpha-cyclodextrin reversibly connected with disulfide bonds. Synthesis and inclusion complexes.BDB Institute of Organic Chemistry and Biochemistry AS CR
17416521 67 Discovery and structure-activity relationship studies of indole derivatives as liver X receptor (LXR) agonists.BDB Tanabe Research Laboratories USA, Inc.
19143565 58 Structural analysis of ARC-type inhibitor (ARC-1034) binding to protein kinase A catalytic subunit and rational design of bisubstrate analogue inhibitors of basophilic protein kinases.BDB University of Tartu
19128055 24 Pyrazolo[1,5-a]-1,3,5-triazine as a purine bioisostere: access to potent cyclin-dependent kinase inhibitor (R)-roscovitine analogue.BDB Universite de Lyon
18790643 42 A study of the structure-activity relationship of GABA(A)-benzodiazepine receptor bivalent ligands by conformational analysis with low temperature NMR and X-ray analysis.BDB University of Wisconsin-Milwaukee
18578471 16 Synthesis and pharmacological evaluation of novel gamma-aminobutyric acid type B (GABAB) receptor agonists as gastroesophageal reflux inhibitors.BDB AstraZeneca
12951118 24 HIV-1 protease inhibitors with picomolar potency against PI-resistant HIV-1 by modification of the P1' substituent.BDB Merck Research Laboratories
12941332 27 6-aryl-pyrazolo[3,4-b]pyridines: potent inhibitors of glycogen synthase kinase-3 (GSK-3).BDB GlaxoSmithKline
12941338 18 Structure-based design of 2-arylamino-4-cyclohexylmethyl-5-nitroso-6-aminopyrimidine inhibitors of cyclin-dependent kinases 1 and 2.BDB University of Newcastle
12646019 48 Discovery of 5-[5-fluoro-2-oxo-1,2- dihydroindol-(3Z)-ylidenemethyl]-2,4- dimethyl-1H-pyrrole-3-carboxylic acid (2-diethylaminoethyl)amide, a novel tyrosine kinase inhibitor targeting vascular endothelial and platelet-derived growth factor receptor tyrosine kinase.BDB SUGEN, Inc.
2552117 68 Tyrphostins I: synthesis and biological activity of protein tyrosine kinase inhibitors.BDB Hebrew University of Jerusalem
18589438 10 Structure of the BH3 domains from the p53-inducible BH3-only proteins Noxa and Puma in complex with Mcl-1.BDB University of Otago
8523406 59 Phenethylthiazolethiourea (PETT) compounds, a new class of HIV-1 reverse transcriptase inhibitors. 1. Synthesis and basic structure-activity relationship studies of PETT analogs.BDB Eli Lilly and Company
1588552 30 HIV-1 protease inhibitors based on hydroxyethylene dipeptide isosteres: an investigation into the role of the P1' side chain on structure-activity.BDB Merck Research Laboratories