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38 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
25752984 32 Design and synthesis of a novel series of [1-(4-hydroxy-benzyl)-1H-indol-5-yloxy]-acetic acid compounds as potent, selective, thyroid hormone receptor▀ agonists.EBI Eli Lilly and Company
24745969 36 Identification of the first potent, selective and bioavailable PPARa antagonist.EBI Inception Sciences
24712661 47 Discovery of 2-[3,5-dichloro-4-(5-isopropyl-6-oxo-1,6-dihydropyridazin-3-yloxy)phenyl]-3,5-dioxo-2,3,4,5-tetrahydro[1,2,4]triazine-6-carbonitrile (MGL-3196), a Highly Selective Thyroid Hormone Receptor▀ agonist in clinical trials for the treatment of dyslipidemia.EBI Madrigal Pharmaceuticals Inc
24290064 44 Synthesis and pharmacological characterization of 1-benzyl-4-aminoindole-based thyroid hormone receptor▀ agonists.EBI Sanwa Kagaku Kenkyusho Co., Ltd
24799995 54 Development of novel Vitamin D Receptor-Coactivator Inhibitors.EBI University of Wisconsin-Milwaukee
23414840 285 Synthesis and evaluation of methylsulfonylnitrobenzamides (MSNBAs) as inhibitors of the thyroid hormone receptor-coactivator interaction.EBI St. Jude Children's Research Hospital
24040486 30 Identification of Potent and Selective Diphenylpropanamide ROR? Inhibitors.EBI New York University School of Medicine
23276448 46 Design, synthesis, and structure-activity relationship (SAR) of N-[7-(4-hydroxyphenoxy)-6-methylindan-4-yl]malonamic acids as thyroid hormone receptorß (TRß) selective agonists.EBI Kissei Pharmaceutical Co., Ltd
17467994 136 2D QSAR studies on thyroid hormone receptor ligands.EBI Universidade de S£o Paulo
17524652 84 QSAR study of selective ligands for the thyroid hormone receptor beta.EBI University of Insubria
22512468 13 Selective thyromimetics using receptor and tissue selectivity approaches: prospects for dyslipidemia.EBI Zydus Research Centre
22324546 55 Synthesis and evaluation of sulfonylnitrophenylthiazoles (SNPTs) as thyroid hormone receptor-coactivator interaction inhibitors.EBI Institut Pasteur Korea
22542282 25 Discovery of novel indane derivatives as liver-selective thyroid hormone receptorß (TRß) agonists for the treatment of dyslipidemia.EBI Kissei Pharmaceutical Co., Ltd
17988877 60 Characterization of thyroid hormone receptor alpha (TRalpha)-specific analogs with varying inner- and outer-ring substituents.EBI University of California San Francisco
15293993 172 Liver-selective glucocorticoid antagonists: a novel treatment for type 2 diabetes.EBI Abbott Laboratories
19900809 12 Thyroid receptor agonists for the treatment of androgenetic alopecia.EBI Pfizer Inc
19469546 208 Improvement of pharmacological properties of irreversible thyroid receptor coactivator binding inhibitors.EBI St. Jude Children's Hospital
18975928 54 Synthesis and biological evaluation of a series of liver-selective phosphonic acid thyroid hormone receptor agonists and their prodrugs.EBI Metabasis Therapeutics Inc
18585912 6 Design and synthesis of novel 3-hydroxy-cyclobut-3-ene-1,2-dione derivatives as thyroid hormone receptor beta (TR-beta) selective ligands.EBI Zydus Research Centre
17878314 8 Targeting thyroid hormone receptor-beta agonists to the liver reduces cholesterol and triglycerides and improves the therapeutic index.EBI Metabasis Therapeutics Inc
16338239 26 Thyroid receptor ligands. Part 5: novel bicyclic agonist ligands selective for the thyroid hormone receptor beta.EBI Karo Bio AB
16099653 28 A new class of high affinity thyromimetics containing a phenyl-naphthylene core.EBI Pharmaceutical Research Institute
15780617 20 Novel heterocyclic thyromimetics.EBI Bayer HealthCare AG
15177480 42 Novel and potent transforming growth factor beta type I receptor kinase domain inhibitor: 7-amino 4-(2-pyridin-2-yl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)-quinolines.EBI Eli Lilly and Company
12825953 12 Structural determinants of selective thyromimetics.EBI University of California
12565933 30 Discovery of a novel series of 6-azauracil-based thyroid hormone receptor ligands: potent, TR beta subtype-selective thyromimetics.EBI Pfizer Inc
12109914 24 Rational design and synthesis of a novel thyroid hormone antagonist that blocks coactivator recruitment.EBI University of California
11806713 8 Synthesis and preliminary characterization of a novel antiarrhythmic compound (KB130015) with an improved toxicity profile compared with amiodarone.EBI Karo Bio AB
11597408 12 A designed antagonist of the thyroid hormone receptor.EBI University of California
15054115 11 DiPOA ([8-(3,3-diphenyl-propyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]dec-3-yl]-acetic acid), a novel, systemically available, and peripherally restricted mu opioid agonist with antihyperalgesic activity: I. In vitro pharmacological characterization and pharmacokinetic properties.BDB Purdue Pharma Discovery Research
14517179 5 WAY-855 (3-amino-tricyclo[]heptane-1,3-dicarboxylic acid): a novel, EAAT2-preferring, nonsubstrate inhibitor of high-affinity glutamate uptake.BDB Wyeth Research
14522054 98 Discovery of inhibitors that elucidate the role of UCH-L1 activity in the H1299 lung cancer cell line.BDB Brigham and Women's Hospital