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26 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
27393949 21 2-Indolylmethylenebenzofuranones as first effective inhibitors of ABCC2.EBI BMSSI UMR 5086 CNRS/Universit£ Lyon 1
22822035 10 Mechanistic studies on the absorption and disposition of scutellarin in humans: selective OATP2B1-mediated hepatic uptake is a likely key determinant for its unique pharmacokinetic characteristics.EBI Chinese Academy of Sciences
23132334 28 In vitro investigations into the roles of drug transporters and metabolizing enzymes in the disposition and drug interactions of dolutegravir, a HIV integrase inhibitor.EBI GlaxoSmithKline
24959892 152 Optimization of pyrrolamide topoisomerase II inhibitors toward identification of an antibacterial clinical candidate (AZD5099).EBI AstraZeneca
25310383 50 Potent nonimmunosuppressive cyclophilin inhibitors with improved pharmaceutical properties and decreased transporter inhibition.EBI Novartis Institutes for Biomedical Research
9321514 1 Biliary excretion of pravastatin in rats: contribution of the excretion pathway mediated by canalicular multispecific organic anion transporter.EBI Toho University School of Pharmaceutical Sciences
9270020 3 Methotrexate is excreted into the bile by canalicular multispecific organic anion transporter in rats.EBI Toho University School of Pharmaceutical Sciences
7945404 2 Hepatobiliary elimination of the peroxisome proliferator nafenopin by conjugation and subsequent ATP-dependent transport across the canalicular membrane.EBI Deutsches Krebsforschungszentrum
9355767 6 ATP-dependent transport of bilirubin glucuronides by the multidrug resistance protein MRP1 and its hepatocyte canalicular isoform MRP2.EBI Deutsches Krebsforschungszentrum
12134946 6 Are MDCK cells transfected with the human MRP2 gene a good model of the human intestinal mucosa?EBI The University of Kansas
15616150 14 Differential interaction of 3-hydroxy-3-methylglutaryl-coa reductase inhibitors with ABCB1, ABCC2, and OATP1B1.EBI Pfizer Inc.
16384552 4 Interaction of ivermectin with multidrug resistance proteins (MRP1, 2 and 3).EBI Laboratoire de Pharmacologie-Toxicologie INRA
10570049 4 Effect of multidrug resistance-reversing agents on transporting activity of human canalicular multispecific organic anion transporter.EBI Kagoshima University
22541068 73 Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.EBI Uppsala University
9495864 2 Carrier-mediated mechanism for the biliary excretion of the quinolone antibiotic grepafloxacin and its glucuronide in rats.EBI University of Tokyo
9756510 4 Reduced folate derivatives are endogenous substrates for cMOAT in rats.EBI University of Tokyo
9067317 2 Temocaprilat, a novel angiotensin-converting enzyme inhibitor, is excreted in bile via an ATP-dependent active transporter (cMOAT) that is deficient in Eisai hyperbilirubinemic mutant rats (EHBR).EBI Sankyo Co., Ltd.
9918561 7 Primary active transport of peptidic endothelin antagonists by rat hepatic canalicular membrane.EBI University of Tokyo
22366653 3 Discovery of GS-9451: an acid inhibitor of the hepatitis C virus NS3/4A protease.EBI Gilead Sciences, Inc.
19170519 34 Potent and selective inhibitors of breast cancer resistance protein (ABCG2) derived from the p-glycoprotein (ABCB1) modulator tariquidar.EBI University of Regensburg
18707884 12 A 4-aminobenzoic acid derivative as novel lead for selective inhibitors of multidrug resistance-associated proteins.EBI University of Bonn
21189339 5 Interaction potential of etravirine with drug transporters assessed in vitro.EBI University Hospital Heidelberg
19725578 20 Modulation of multidrug resistance protein 1 (MRP1/ABCC1)-mediated multidrug resistance by bivalent apigenin homodimers and their derivatives.EBI The Hong Kong Polytechnic University
18457386 1 Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).EBI Uppsala University
15665139 3 Vectorial transport of the peptide CCK-8 by double-transfected MDCKII cells stably expressing the organic anion transporter OATP1B3 (OATP8) and the export pump ABCC2.BDB German Cancer Research Center