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66 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
24456288 2 De-novo designed library of benzoylureas as inhibitors of BCL-XL: synthesis, structural and biochemical characterization.EBI The Walter and Eliza Hall Institute of Medical Research
23200243 5 Fluorescent ligands for adenosine receptors.EBI National Institute of Diabetes and Digestive and Kidney Diseases
23789857 19 Rational design of sulfonated A3 adenosine receptor-selective nucleosides as pharmacological tools to study chronic neuropathic pain.EBI National Institute of Diabetes and Digestive and Kidney Diseases
17418915 48 QSAR study on a novel series of 8-azaadenine analogues proposed as A1 adenosine receptor antagonists.EBI University of Pisa
2016708 26 2-aralkoxyadenosines: potent and selective agonists at the coronary artery A2 adenosine receptor.EBI University of South Florida
22559880 52 Structure-guided design of A(3) adenosine receptor-selective nucleosides: combination of 2-arylethynyl and bicyclo[3.1.0]hexane substitutions.EBI National Institute of Diabetes and Digestive and Kidney Diseases
20188574 141 2-Amino-5-benzoyl-4-phenylthiazoles: Development of potent and selective adenosine A1 receptor antagonists.EBI University of Bonn
18424135 131 Design of (N)-methanocarba adenosine 5'-uronamides as species-independent A3 receptor-selective agonists.EBI National Institute of Diabetes and Digestive and Kidney Diseases
17933541 145 5'-Carbamoyl derivatives of 2'-C-methyl-purine nucleosides as selective A1 adenosine receptor agonists: affinity, efficacy, and selectivity for A1 receptor from different species.EBI Universit£ di Camerino
15743197 37 Synthesis, biological evaluation, and molecular modeling of ribose-modified adenosine analogues as adenosine receptor agonists.EBI Universit£ di Camerino
15214785 58 1,2,4-triazolo[4,3-a]quinoxalin-1-one moiety as an attractive scaffold to develop new potent and selective human A3 adenosine receptor antagonists: synthesis, pharmacological, and ligand-receptor modeling studies.EBI Universit£ degli Studi di Firenze
12383013 44 Synthesis, molecular modeling studies, and pharmacological activity of selective A(1) receptor antagonists.EBI Universit£ degli Studi di Genova
11462973 47 3-Aryl[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-ones: a new class of selective A1 adenosine receptor antagonists.EBI Universit£ di Pisa
10956189 98 A novel class of highly potent and selective A1 adenosine antagonists: structure-affinity profile of a series of 1,8-naphthyridine derivatives.EBI Universit£ di Pisa
9572897 49 2'-C-Methyl analogues of selective adenosine receptor agonists: synthesis and binding studies.EBI Universit£ di Camerino
8246243 5 Photoisomerization of a potent and selective adenosine A2 antagonist, (E)-1,3-Dipropyl-8-(3,4-dimethoxystyryl)-7-methylxanthine.EBI Kyowa Hakko Kogyo Co., Ltd.
8355252 31 Adenosine A1 antagonists. 3. Structure-activity relationships on amelioration against scopolamine- or N6-((R)-phenylisopropyl)adenosine-induced cognitive disturbance.EBI Kyowa Hakko Kogyo Co., Ltd.
1548682 74 8-Polycycloalkyl-1,3-dipropylxanthines as potent and selective antagonists for A1-adenosine receptors.EBI Kyowa Hakko Kogyo Co., Ltd.
1738138 58 Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential.EBI NIDDK
1469688 31 2-(N'-aralkylidenehydrazino)adenosines: potent and selective coronary vasodilators.EBI University of South Florida
1433217 21 Synthesis and biological activity of N6-(p-sulfophenyl)alkyl and N6-sulfoalkyl derivatives of adenosine: water-soluble and peripherally selective adenosine agonists.EBI National Institute of Diabetes
1501234 55 Adenosine A1 antagonists. 2. Structure-activity relationships on diuretic activities and protective effects against acute renal failure.EBI Kyowa Hakko Kogyo Co., Ltd.
2016707 34 2-Alkoxyadenosines: potent and selective agonists at the coronary artery A2 adenosine receptor.EBI University of South Florida
2002461 26 1H-imidazo[4,5-c]quinolin-4-amines: novel non-xanthine adenosine antagonists.EBI Center for Bio-Pharmaceutical Sciences
2709373 51 Electrophilic derivatives of purines as irreversible inhibitors of A1 adenosine receptors.EBI NIDDK
3351850 32 125I-labeled 8-phenylxanthine derivatives: antagonist radioligands for adenosine A1 receptors.EBI University of Virginia School of Medicine
2991519 98 Synthesis of xanthines as adenosine antagonists, a practical quantitative structure-activity relationship application.EBI TBA
6279840 17 Adenosine receptors: targets for future drugs.EBI TBA
15203164 38 Structure-affinity relationships of 5'-aromatic ethers and 5'-aromatic sulfides as partial A1 adenosine agonists, potential supraventricular anti-arrhythmic agents.EBI CV Therapeutics, Inc.
10714510 36 The discovery and synthesis of highly potent, A2a receptor agonists.EBI Glaxo Wellcome Medicines Research Centre
21401121 16 The identification of the 2-phenylphthalazin-1(2H)-one scaffold as a new decorable core skeleton for the design of potent and selective human A3 adenosine receptor antagonists.EBI Universita` degli Studi di Firenze
20937560 54 Pyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-ones as selective human A(1) adenosine receptor ligands.EBI Dipartimento di Scienze Farmaceutiche
19301821 55 Pyrido[2,3-e]-1,2,4-triazolo[4,3-a]pyrazin-1-one as a new scaffold to develop potent and selective human A3 adenosine receptor antagonists. Synthesis, pharmacological evaluation, and ligand-receptor modeling studies.EBI Universita di Firenze
18468446 55 Synthesis, ligand-receptor modeling studies and pharmacological evaluation of novel 4-modified-2-aryl-1,2,4-triazolo[4,3-a]quinoxalin-1-one derivatives as potent and selective human A3 adenosine receptor antagonists.EBI Universita' di Firenze
17028066 41 Synthesis, biological activity and molecular modelling of new trisubstituted 8-azaadenines with high affinity for A1 adenosine receptors.EBI Università di Pisa
16789747 71 4-amido-2-aryl-1,2,4-triazolo[4,3-a]quinoxalin-1-ones as new potent and selective human A3 adenosine receptor antagonists. synthesis, pharmacological evaluation, and ligand-receptor modeling studies.EBI Università di Firenze
16335918 68 1,2,4-Triazolo[1,5-a]quinoxaline as a versatile tool for the design of selective human A3 adenosine receptor antagonists: synthesis, biological evaluation, and molecular modeling studies of 2-(hetero)aryl- and 2-carboxy-substituted derivatives.EBI Università degli Studi di Firenze
16279775 61 Synthesis and 3D QSAR of new pyrazolo[3,4-b]pyridines: potent and selective inhibitors of A1 adenosine receptors.EBI Università degli Studi di Siena
16099648 128 1,8-Naphthyridin-4-one derivatives as new ligands of A2A adenosine receptors.EBI Dipartimento di Scienze Farmaceutiche
15163184 227 Study on affinity profile toward native human and bovine adenosine receptors of a series of 1,8-naphthyridine derivatives.EBI Università di Pisa
12408725 1 Synthesis and evaluation of no-carrier-added 8-cyclopentyl-3-(3-[(18)F]fluoropropyl)-1-propylxanthine ([(18)F]CPFPX): a potent and selective A(1)-adenosine receptor antagonist for in vivo imaging.EBI Forschungszentrum Jülich GmbH
12408713 54 Design, synthesis and biological evaluation of novel N-alkyl- and N-acyl-(7-substituted-2-phenylimidazo[1,2-a][1,3,5]triazin-4-yl)amines (ITAs) as novel A(1) adenosine receptor antagonists.EBI Università di Pisa
11549462 11 Synthesis and biological data of 4-amino-1-(2-chloro-2-phenylethyl)-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl esters, a new series of A1-adenosine receptor (A1AR) ligands.EBI Facoltà di Farmacia dell'Università degli Studi di Genova
10956220 93 Synthesis and structure-activity relationships of a new set of 2-arylpyrazolo[3,4-c]quinoline derivatives as adenosine receptor antagonists.EBI Universita' di Firenze
10737748 81 1,2,4-Triazolo[4,3-a]quinoxalin-1-one: a versatile tool for the synthesis of potent and selective adenosine receptor antagonists.EBI Universita' di Firenze
9513594 41 Novel 3-aralkyl-7-(amino-substituted)-1,2,3-triazolo[4,5-d]pyrimidines with high affinity toward A1 adenosine receptors.EBI Università di Pisa
9484505 12 A1 adenosine receptor antagonists as ligands for positron emission tomography (PET) and single-photon emission tomography (SPET).EBI Forschungszentrum Jülich GmbH
9191953 11 Synthesis and biological evaluation of the enantiomers of the potent and selective A1-adenosine antagonist 1,3-dipropyl-8-[2-(5,6-epoxynorbonyl)]-xanthine.EBI CV Therapeutics
8809156 2 Synthesis and cardiotonic activity of novel pyrimidine derivatives: crystallographic and quantum chemical studies.EBI Università di Padova
8496906 43 Bronchodilator activity of xanthine derivatives substituted with functional groups at the 1- or 7-position.EBI Hokuriku University
8071944 37 8-Azaxanthine derivatives as antagonists of adenosine receptors.EBI Università di Camerino
6315938 1 Neurotransmitter receptor binding and drug discovery.EBI TBA
1992150 30 8-(Dicyclopropylmethyl)-1,3-dipropylxanthine: a potent and selective adenosine A1 antagonist with renal protective and diuretic activities.EBI Kyowa Hakko Kogyo Co., Ltd.
1613758 52 (E)-1,3-dialkyl-7-methyl-8-(3,4,5-trimethoxystyryl)xanthines: potent and selective adenosine A2 antagonists.EBI Kyowa Hakko Kogyo Co., Ltd
1469687 21 2-(N'-alkylidenehydrazino)adenosines: potent and selective coronary vasodilators.EBI University of South Florida
1404238 7 7,8-Dihydro-8-ethyl-2-(3-noradamantyl)-4-propyl-1H-imidazo[2,1-i]purin-5(4H)-one: a potent and water-soluble adenosine A1 antagonist.EBI Kyowa Hakko Kogyo Co., Ltd.
1331453 75 Effects of alkyl substitutions of xanthine skeleton on bronchodilation.EBI Hokuriku University
17221184 55 Synthesis and in vivo evaluation of a novel 5-HT1A receptor agonist radioligand [O-methyl- 11C]2-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-4-methyl-1,2,4-triazine-3,5(2H,4H)dione in nonhuman primates.BDB Columbia University
8386236 11 In vitro and in vivo pharmacological characterization of N6-cyclopentyl-9-methyladenine (N-0840): a selective, orally active A1 adenosine receptor antagonist.BDB Whitby Research, Inc.
2997628 56 Xanthine derivatives as antagonists at A1 and A2 adenosine receptors.BDB TBA
2825043 23 8-Cyclopentyl-1,3-dipropylxanthine (DPCPX)--a selective high affinity antagonist radioligand for A1 adenosine receptors.BDB Universität Heidelberg
2067592 83 Comparison of A1 adenosine receptors in brain from different species by radioligand binding and photoaffinity labelling.BDB Universität Heidelberg
1661335 95 Receptor binding profiles of amiloride analogues provide no evidence for a link between receptors and the Na+/H+ exchanger, but indicate a common structure on receptor proteins.BDB Center for Bio-Pharmaceutical Sciences