The following articles (labelled with PubMed ID or TBD) are for your review
||Therapeutic Potential of 5-HT6 Receptor Agonists.
||Universit£ de Caen Basse-Normandie
||Synthesis and biological evaluation of 2-aryliminopyrrolidines as selective ligands for I1 imidazoline receptors: discovery of new sympatho-inhibitory hypotensive agents with potential beneficial effects in metabolic syndrome.
||Universit£ de Strasbourg
||a2-adrenoceptor antagonists: synthesis, pharmacological evaluation, and molecular modeling investigation of pyridinoguanidine, pyridino-2-aminoimidazoline and their derivatives.
||Targeting dopamine D3 and serotonin 5-HT1A and 5-HT2A receptors for developing effective antipsychotics: synthesis, biological characterization, and behavioral studies.
||Universit£ degli Studi di Siena
||N-arylpiperazinyl-N'-propylamino derivatives of heteroaryl amides as functional uroselective alpha 1-adrenoceptor antagonists.
||Pyrrolizidine esters and amides as 5-HT4 receptor agonists and antagonists.
||Azaadamantane benzamide 5-HT4 agonists: gastrointestinal prokinetic SC-54750.
||Selective optimization of side activities: another way for drug discovery.
||Prestwick Chemical Inc.
||A novel and selective 5-HT2 receptor agonist with ocular hypotensive activity: (S)-(+)-1-(2-aminopropyl)-8,9-dihydropyrano[3,2-e]indole.
||Alcon Research, Ltd.
||A series of 6- and 7-piperazinyl- and -piperidinylmethylbenzoxazinones with dopamine D4 antagonist activity: discovery of a potential atypical antipsychotic agent.
||Synthesis and pharmacologic evaluation of 2-endo-amino-3-exo-isopropylbicyclo[2.2.1]heptane: a potent imidazoline1 receptor specific agent.
||Two novel and potent 3-[(o-methoxyphenyl)piperazinylethyl]-5-phenylthien.
||Synthesis and structure--activity relationship in a class of indolebutylpiperazines as dual 5-HT(1A) receptor agonists and serotonin reuptake inhibitors.
||Indolebutylamines as selective 5-HT(1A) agonists.
||Binding of beta-carbolines at imidazoline I2 receptors: a structure-affinity investigation.
||Virginia Commonwealth University
||Design, synthesis, and structure-activity relationships of phthalimide-phenylpiperazines: a novel series of potent and selective alpha(1)(a)-adrenergic receptor antagonists.
||The R.W. Johnson Pharmaceutical Research Institute
||Alpha(2) adrenoceptor agonists as potential analgesic agents. 2. Discovery of 4-(4-imidazo)-1,3-dimethyl-6,7-dihydro-thianaphthene as a high-affinity ligand for the alpha(2D) adrenergic receptor.
||The R. W. Johnson Pharmaceutical Research Institute
||Synthesis and pharmacological characterization of 3-[2-((3aR,9bR)-cis-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benz[e] isoindol-2-yl)ethyl]pyrido-[3',4':4,5]thieno[3,2-d]pyrimidine-2,4 (1H,3H)-dione (A-131701): a uroselective alpha 1A adrenoceptor antagonist for the symptomatic treatment of benign pr
||Synthesis and evaluation of 2-(arylamino)imidazoles as alpha 2-adrenergic agonists.
||Synthesis and evaluation of 2-[(5-methylbenz-1-ox-4-azin-6-yl)imino]imidazoline, a potent, peripherally acting alpha 2 adrenoceptor agonist.
||Synthesis and structure-activity relationships of N-propyl-N-(4-pyridinyl)-1H-indol-1-amine (besipirdine) and related analogs as potential therapeutic agents for Alzheimer's disease.
||Hoechst-Roussel Pharmaceuticals Inc.
||Design, synthesis, and structure-activity relationships of a new series of alpha-adrenergic agonists: spiro[(1,3-diazacyclopent-1-ene)-5,2'-(1',2',3',4'- tetrahydronaphthalene)].
||Institut de Recherches Servier
||OPC-28326, a selective femoral vasodilator, is an alpha2C-adrenoceptor-selective antagonist.
||Otsuka Maryland Research Institute
||RS-102221: a novel high affinity and selective, 5-HT2C receptor antagonist.
||Novel discriminatory ligands for 5-HT2B receptors.
||SmithKline Beecham Pharmaceuticals
||Pharmacological characterization of two novel and potent 5-HT4 receptor agonists, RS 67333 and RS 67506, in vitro and in vivo.
||Syntex Discovery Research
||Characterization of the alpha-2C adrenergic receptor subtype in the opossum kidney and in the OK cell line.
||University of Nebraska
||Pharmacological characteristics of alpha 2-adrenergic receptors: comparison of pharmacologically defined subtypes with subtypes identified by molecular cloning.
||University of Nebraska