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15 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
25695864 35 Identification of novel aldose reductase inhibitors based on carboxymethylated mercaptotriazinoindole scaffold.EBI Slovak Academy of Sciences
25375908 9 Targeting aldose reductase for the treatment of diabetes complications and inflammatory diseases: new insights and future directions.EBI Universit£ degli Studi di Messina
8893834 30 Synthesis, activity, and molecular modeling of a new series of tricyclic pyridazinones as selective aldose reductase inhibitors.EBI TBA
1900532 44 A highly specific aldose reductase inhibitor, ethyl 1-benzyl-3-hydroxy-2(5H)-oxopyrrole-4-carboxylate, and its congeners.EBI Pfizer Inc.
22104435 54 Design, synthesis, and biological evaluation of novel (1-thioxo-1,2,3,4-tetrahydro-ß-carbolin-9-yl)acetic acids as selective inhibitors for AKR1B1.EBI University of Toyama
20936791 32 A diverse series of substituted benzenesulfonamides as aldose reductase inhibitors with antioxidant activity: design, synthesis, and in vitro activity.EBI Aristotle University of Thessaloniki
20304656 31 Chromene-3-carboxamide derivatives discovered from virtual screening as potent inhibitors of the tumour maker, AKR1B10.EBI Gifu Pharmaceutical University
20036445 2 Structure of aldehyde reductase in ternary complex with a 5-arylidene-2,4-thiazolidinedione aldose reductase inhibitor.EBI Monash University (Parkville Campus)
20189816 8 Design and synthesis of novel series of pyrrole based chemotypes and their evaluation as selective aldose reductase inhibitors. A case of bioisosterism between a carboxylic acid moiety and that of a tetrazole.EBI Aristotle University of Thessaloniki
19121944 4 Correlation of binding constants and molecular modelling of inhibitors in the active sites of aldose reductase and aldehyde reductase.EBI Monash University (Parkville Campus)
16107153 10 Structure of aldehyde reductase holoenzyme in complex with the potent aldose reductase inhibitor fidarestat: implications for inhibitor binding and selectivity.EBI Monash University (Parkville Campus)
12672241 37 Novel, highly potent aldose reductase inhibitors: cyano(2-oxo-2,3-dihydroindol-3-yl)acetic acid derivatives.EBI Università di Pisa
10882376 7 A potent aldose reductase inhibitor, (2S,4S)-6-fluoro-2', 5'-dioxospiro[chroman-4,4'-imidazolidine]-2-carboxamide (Fidarestat): its absolute configuration and interactions with the aldose reductase by X-ray crystallography.EBI Rational Drug Design Laboratories
9057855 33 Highly selective aldose reductase inhibitors. 3. Structural diversity of 3-(arylmethyl)-2,4,5-trioxoimidazolidine-1-acetic acids.EBI Nippon Zoki Pharmaceutical Company Ltd.
15857120 81 Discovery of 3-[(4,5,7-trifluorobenzothiazol-2-yl)methyl]indole-N-acetic acid (lidorestat) and congeners as highly potent and selective inhibitors of aldose reductase for treatment of chronic diabetic complications.BDB The Institute for Diabetes Discovery