BindingDB logo
myBDB logout

265 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
28011206 36 Design, synthesis and biological evaluation of 4'-aminochalcone-rivastigmine hybrids as multifunctional agents for the treatment of Alzheimer's disease.EBI Sichuan University
27923535 39 Multitarget drug design strategy against Alzheimer's disease: Homoisoflavonoid Mannich base derivatives serve as acetylcholinesterase and monoamine oxidase B dual inhibitors with multifunctional properties.EBI Sichuan University
27908752 55 N-Propargylpiperidines with naphthalene-2-carboxamide or naphthalene-2-sulfonamide moieties: Potential multifunctional anti-Alzheimer's agents.EBI University of Ljubljana
27692996 84 Neuroprotective effects of benzyloxy substituted small molecule monoamine oxidase B inhibitors in Parkinson's disease.EBI China Pharmaceutical University
26471320 50 Donepezil-like multifunctional agents: Design, synthesis, molecular modeling and biological evaluation.EBI Okayama University
27267007 58 New cinnamic - N-benzylpiperidine and cinnamic - N,N-dibenzyl(N-methyl)amine hybrids as Alzheimer-directed multitarget drugs with antioxidant, cholinergic, neuroprotective and neurogenic properties.EBI Instituto de Qu£mica M£dica
27578245 46 2-Benzylidene-1-indanone derivatives as inhibitors of monoamine oxidase.EBI North-West University
27135371 26 (E)-3-Heteroarylidenechroman-4-ones as potent and selective monoamine oxidase-B inhibitors.EBI Universit£ di Roma
27079124 22 Synthesis and evaluation of 4-hydroxyl aurone derivatives as multifunctional agents for the treatment of Alzheimer's disease.EBI Sichuan University
26710088 248 Recent Progress in Histone Demethylase Inhibitors.EBI University of Oxford
26819666 26 Monoamine Oxidase Inhibitory Activity of Novel Pyrazoline Analogues: Curcumin Based Design and Synthesis.EBI Birla Institute of Technology
26702542 59 Discovery of a Novel Inhibitor of Histone Lysine-Specific Demethylase 1A (KDM1A/LSD1) as Orally Active Antitumor Agent.EBI European Institute of Oncology
26974383 11 Design and synthesis of novel chalcones as potent selective monoamine oxidase-B inhibitors.EBI Qatar University
26700437 32 Identification of SNAIL1 Peptide-Based Irreversible Lysine-Specific Demethylase 1-Selective Inactivators.EBI Kyoto Prefectural University of Medicine
26964672 26 Novel tricyclic pyrazolo[1,5-d][1,4]benzoxazepin-5(6H)-one: Design, synthesis, model and use as hMAO-B inhibitors.EBI Anhui Medical University
26717204 17 Drug design, synthesis, inávitro and in silico evaluation of selective monoaminoxidase B inhibitors based on 3-acetyl-2-dichlorophenyl-5-aryl-2,3-dihydro-1,3,4-oxadiazole chemical scaffold.EBI Universit£ degli Studi di Cagliari
26917219 63 Design, synthesis and biological evaluation of novel donepezil-coumarin hybrids as multi-target agents for the treatment of Alzheimer's disease.EBI China Pharmaceutical University
26821818 25 Inhibition of monoamine oxidase by benzoxathiolone analogues.EBI North-West University
26652247 60 3-(Piperidin-4-ylmethoxy)pyridine Containing Compounds Are Potent Inhibitors of Lysine Specific Demethylase 1.EBI Baylor College of Medicine
26432037 14 Monoamine oxidase inhibitory activities of heterocyclic chalcones.EBI North-West University
26352677 44 Novel 2H-chromen-2-one derivatives of resveratrol: Design, synthesis, modeling and use as human monoamine oxidase inhibitors.EBI Hefei University of Technology
26086931 38 Strategies for the Discovery of Target-Specific or Isoform-Selective Modulators.EBI Shandong University
26337020 69 Synthesis of a series of unsaturated ketone derivatives as selective and reversible monoamine oxidase inhibitors.EBI Korea Institute of Science and Technology
26278660 90 Evaluation of Homobivalent Carbolines as Designed Multiple Ligands for the Treatment of Neurodegenerative Disorders.EBI University of Jena
25915162 12 New Frontiers in Selective Human MAO-B Inhibitors.EBI Sapienza Universit£ di Roma
25934229 21 Synthesis and evaluation of selegiline derivatives as monoamine oxidase inhibitor, antioxidant and metal chelator against Alzheimer's disease.EBI Sun Yat-sen University
25922182 80 Synthesis and evaluation of quinazoline amino acid derivatives as mono amine oxidase (MAO) inhibitors.EBI Alexandria University
26107513 172 Structure-Based Design and Optimization of Multitarget-Directed 2H-Chromen-2-one Derivatives as Potent Inhibitors of Monoamine Oxidase B and Cholinesterases.EBI Universit£ degli Studi di Bari"Aldo Moro"
25466194 34 a-Ketoamino acid ester derivatives as promising MAO inhibitors.EBI King Saud University
25699146 13 Pure Diastereomers of a Tranylcypromine-Based LSD1 Inhibitor: Enzyme Selectivity and In-Cell Studies.EBI Sapienza University of Roma
25812965 80 Multi-target tacrine-coumarin hybrids: cholinesterase and monoamine oxidase B inhibition properties against Alzheimer's disease.EBI China Pharmaceutical University
25768700 30 Pure enantiomers of benzoylamino-tranylcypromine: LSD1 inhibition, gene modulation in human leukemia cells and effects on clonogenic potential of murine promyelocytic blasts.EBI Sapienza University of Roma
25732770 12 Synthesis, biological investigation and molecular docking study of N-malonyl-1,2-dihydroisoquinoline derivatives as brain specific and shelf-stable MAO inhibitors.EBI Assiut University
25627172 150 Novel arylalkenylpropargylamines as neuroprotective, potent, and selective monoamine oxidase B inhibitors for the treatment of Parkinson's disease.EBI A* STAR (Agency of Science, Technology and Research)
25610955 53 Design, synthesis, and structure-activity relationship of novel LSD1 inhibitors based on pyrimidine-thiourea hybrids as potent, orally active antitumor agents.EBI Zhengzhou University
25707011 52 Exploring new selective 3-benzylquinoxaline-based MAO-A inhibitors: design, synthesis, biological evaluation and docking studies.EBI Alexandria University
25418133 51 N-Methyl-N-((1-methyl-5-(3-(1-(2-methylbenzyl)piperidin-4-yl)propoxy)-1H-indol-2-yl)methyl)prop-2-yn-1-amine, a new cholinesterase and monoamine oxidase dual inhibitor.EBI Laboratorio de Qu�mica M�dica, (IQOG, CSIC)
25857942 30 The synthesis and evaluation of sesamol and benzodioxane derivatives as inhibitors of monoamine oxidase.EBI North-West University
25827526 33 Histone H3 peptide based LSD1-selective inhibitors.EBI Waseda University
25725609 18 Structure-activity study for (bis)ureidopropyl- and (bis)thioureidopropyldiamine LSD1 inhibitors with 3-5-3 and 3-6-3 carbon backbone architectures.EBI John Hopkins University
25600407 26 Reversible and irreversible small molecule inhibitors of monoamine oxidase B (MAO-B) investigated by biophysical techniques.EBI Dart NeuroScience, LLC
25701250 32 Inhibition of monoamine oxidase by indole-5,6-dicarbonitrile derivatives.EBI Yaroslavl State Technical University
25542589 23 Multifunctional coumarin derivatives: monoamine oxidase B (MAO-B) inhibition, anti-▀-amyloid (A▀) aggregation and metal chelation properties against Alzheimer's disease.EBI China Pharmaceutical University
25541201 55 Design and synthesis of novel 2-pyrazoline-1-ethanone derivatives as selective MAO inhibitors.EBI Anhui Medical University
24986657 56 Synthesis of some novel hydrazone and 2-pyrazoline derivatives: monoamine oxidase inhibitory activities and docking studies.EBI Ministry of Health of Turkey
24955776 166 Indazole- and indole-5-carboxamides: selective and reversible monoamine oxidase B inhibitors with subnanomolar potency.EBI University of Bonn
25532905 10 Potent and selective MAO-B inhibitory activity: amino- versus nitro-3-arylcoumarin derivatives.EBI Universidad de Santiago de Compostela
25488845 4 Radiosynthesis and ex vivo evaluation of [(18)F]-(S)-3-(6-(3-fluoropropoxy)benzo[d]isoxazol-3-yl)-5-(methoxymethyl)oxazolidin-2-one for imaging MAO-B with PET.EBI University of Toronto
25462230 80 In silico design of novel 2H-chromen-2-one derivatives as potent and selective MAO-B inhibitors.EBI Universit£ degli Studi di Bari"Aldo Moro"
25173853 50 Synthesis, biological activity and mechanistic insights of 1-substituted cyclopropylamine derivatives: a novel class of irreversible inhibitors of histone demethylase KDM1A.EBI European Institute of Oncology
24904963 18 New insights into the biological properties of Crocus sativus L.: chemical modifications, human monoamine oxidases inhibition and molecular modeling studies.EBI Sapienza University of Rome
24856304 25 New coumarin derivatives: design, synthesis and use as inhibitors of hMAO.EBI Anhui Medical University
24813882 41 Donepezil + propargylamine + 8-hydroxyquinoline hybrids as new multifunctional metal-chelators, ChE and MAO inhibitors for the potential treatment of Alzheimer's disease.EBI Okayama University
24794105 38 a-Tetralone derivatives as inhibitors of monoamine oxidase.EBI North-West University
24793878 25 New 2H-chromene-3-carboxamide derivatives: design, synthesis and use as inhibitors of hMAO.EBI Anhui Medical University
24746464 29 Identification of the stereochemical requirements in the 4-aryl-2-cycloalkylidenhydrazinylthiazole scaffold for the design of selective human monoamine oxidase B inhibitors.EBI Sapienza University of Rome
24187998 96 Design, synthesis, and biological evaluation of Erythrina alkaloid analogues as neuronal nicotinic acetylcholine receptor antagonists.EBI University of Copenhagen
23454517 56 A novel series of tacrine-selegiline hybrids with cholinesterase and monoamine oxidase inhibition activities for the treatment of Alzheimer's disease.EBI Sun Yat-sen University
23211968 7 Synthesis and biological evaluation of novel propargyl amines as potential fluorine-18 labeled radioligands for detection of MAO-B activity.EBI Karolinska Institutet
23207410 42 1,5-Diphenylpenta-2,4-dien-1-ones as potent and selective monoamine oxidase-B inhibitors.EBI Sapienza - Universit£ di Roma
23437843 30 Discovery, biological evaluation, and structure-activity and -selectivity relationships of 6'-substituted (E)-2-(benzofuran-3(2H)-ylidene)-N-methylacetamides, a novel class of potent and selective monoamine oxidase inhibitors.EBI Universit£ degli Studi di Bari"Aldo Moro"
23337801 24 Synthesis and SAR study of new thiazole derivatives as vascular adhesion protein-1 (VAP-1) inhibitors for the treatment of diabetic macular edema.EBI Astellas Pharma Inc.
23281824 118 Synthesis of (E)-8-(3-chlorostyryl)caffeine analogues leading to 9-deazaxanthine derivatives as dual A(2A) antagonists/MAO-B inhibitors.EBI Universit£ degli Studi di Parma
16884303 27 Structural insights into monoamine oxidase inhibitory potency and selectivity of 7-substituted coumarins from ligand- and target-based approaches.EBI Universit£ di Bari
11543689 34 Coumarins derivatives as dual inhibitors of acetylcholinesterase and monoamine oxidase.EBI Universit£ de Lausanne
15203146 30 Inhibition of monoamine oxidases by coumarin-3-acyl derivatives: biological activity and computational study.EBI Universit£ degli Studi di Roma 'La Sapienza'
12443774 12 Natural and synthetic geiparvarins are strong and selective MAO-B inhibitors. Synthesis and SAR studies.EBI University of Bari
22705191 45 Inhibition of monoamine oxidase by 8-phenoxymethylcaffeine derivatives.EBI North-West University
20934874 16 Synthesis and molecular modelling studies of prenylated pyrazolines as MAO-B inhibitors.EBI Universit£ di Roma La Sapienza P.le Aldo Moro
18281126 56 Synthesis, molecular modeling studies and selective inhibitory activity against MAO of N1-propanoyl-3,5-diphenyl-4,5-dihydro-(1H)-pyrazole derivatives.EBI Universit£ La Sapienza
17266193 2 Monoamine oxidase isoform-dependent tautomeric influence in the recognition of 3,5-diaryl pyrazole inhibitors.EBI Universit£ di Roma"La Sapienza"
17034132 122 Impact of species-dependent differences on screening, design, and development of MAO B inhibitors.EBI University of Geneva
11123983 112 Inhibition of monoamine oxidases by functionalized coumarin derivatives: biological activities, QSARs, and 3D-QSARs.EBI Universit£ de Lausanne
23122934 44 Inhibition of monoamine oxidase by 8-[(phenylethyl)sulfanyl]caffeine analogues.EBI North-West University
23122857 49 Sulfanylphthalonitrile analogues as selective and potent inhibitors of monoamine oxidase B.EBI North-West University
23102654 20 Inhibition of monoamine oxidase by derivatives of piperine, an alkaloid from the pepper plant Piper nigrum, for possible use in Parkinson's disease.EBI Northeast Ohio Medical University
23153282 70 Synthesis of new 7-oxycoumarin derivatives as potent and selective monoamine oxidase A inhibitors.EBI National Research Center
22978824 17 Multitarget-directed benzylideneindanone derivatives: anti-ß-amyloid (Aß) aggregation, antioxidant, metal chelation, and monoamine oxidase B (MAO-B) inhibition properties against Alzheimer's disease.EBI Sun Yat-sen University
23010267 23 Novel sulfanylphthalimide analogues as highly potent inhibitors of monoamine oxidase B.EBI North-West University
23153812 68 Recent advances in the development of selective human MAO-B inhibitors: (hetero)arylidene-(4-substituted-thiazol-2-yl)hydrazines.EBI Universit£ degli Studi di Roma La Sapienza
22850212 30 Selected chromone derivatives as inhibitors of monoamine oxidase.EBI North-West University
22781190 102 Synthesis and evaluation of aplysinopsin analogs as inhibitors of human monoamine oxidase A and B.EBI University of Mississippi
22385498 24 Synthesis and evaluation of a set of para-substituted 4-phenylpiperidines and 4-phenylpiperazines as monoamine oxidase (MAO) inhibitors.EBI NeuroSearch Sweden AB
22595173 68 The discovery and development of selective 3-fluoro-4-aryloxyallylamine inhibitors of the amine oxidase activity of semicarbazide-sensitive amine oxidase/vascular adhesion protein-1 (SSAO/VAP-1).EBI Pharmaxis Ltd.
22436387 4 Synthesis and evaluation of [¹8F]fluororasagiline, a novel positron emission tomography (PET) radioligand for monoamine oxidase B (MAO-B).EBI Karolinska Institutet
22503231 66 Multipotent MAO and cholinesterase inhibitors for the treatment of Alzheimer's disease: synthesis, pharmacological analysis and molecular modeling of heterocyclic substituted alkyl and cycloalkyl propargyl amine.EBI Laboratorio de Radicales Libres y Qu�mica Computacional (IQOG, CSIC)
22475561 42 Synthesis and inhibitory effect of piperine derivates on monoamine oxidase.EBI General Hospital of PLA
21742494 44 Structure-activity relationship and docking studies of thiazolidinedione-type compounds with monoamine oxidase B.EBI Northeastern Ohio Universities Colleges of Medicine and Pharmacy
21726069 98 Tryptophan 2,3-dioxygenase (TDO) inhibitors. 3-(2-(pyridyl)ethenyl)indoles as potential anticancer immunomodulators.EBI University of Namur
21175212 3 Interactions of monoamine oxidases with the antiepileptic drug zonisamide: specificity of inhibition and structure of the human monoamine oxidase B complex.EBI University of Pavia
20875743 90 Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: design, synthesis, and structure-activity relaEBI Pfizer Inc.
20708306 68 Synthesis of new series of quinoxaline based MAO-inhibitors and docking studies.EBI Alexandria University
20579890 111 Synthesis, semipreparative HPLC separation, biological evaluation, and 3D-QSAR of hydrazothiazole derivatives as human monoamine oxidase B inhibitors.EBI Dipartimento di Chimica e Tecnologie del Farmaco Universit£ degli Studi di Roma La Sapienza
20650633 12 Identification of novel monoamine oxidase B inhibitors by structure-based virtual screening.EBI Northeastern Ohio Universities
20123154 48 2-Arylthiomorpholine derivatives as potent and selective monoamine oxidase B inhibitors.EBI University of Chile
19243954 36 Naphthylisopropylamine and N-benzylamphetamine derivatives as monoamine oxidase inhibitors.EBI University of Chile
18272363 7 Potent, nonpeptide inhibitors of human mast cell tryptase. Synthesis and biological evaluation of novel spirocyclic piperidine amide derivatives.EBI Johnson& Johnson Pharmaceutical Research& Development
18181565 71 Multi-target-directed ligands to combat neurodegenerative diseases.EBI University of Bologna
17611112 36 A new therapeutic approach in Alzheimer disease: some novel pyrazole derivatives as dual MAO-B inhibitors and antiinflammatory analgesics.EBI Hacettepe University
16570912 24 Design, synthesis, and biological evaluation of semicarbazide-sensitive amine oxidase (SSAO) inhibitors with anti-inflammatory activity.EBI La Jolla Pharmaceutical Company
15689151 112 Alkylamino derivatives of 4-aminomethylpyridine as inhibitors of copper-containing amine oxidases.EBI Universit£ di Genova
15537343 4 Fluorinated phenylcyclopropylamines. 2. Effects of aromatic ring substitution and of absolute configuration on inhibition of microbial tyramine oxidase.EBI Universit£t M£nster
15056004 36 Synthesis and selective inhibitory activity of 1-acetyl-3,5-diphenyl-4,5-dihydro-(1H)-pyrazole derivatives against monoamine oxidase.EBI Universit£ degli Studi di Roma La Sapienza
15027872 7 Fluorinated phenylcyclopropylamines. 1. Synthesis and effect of fluorine substitution at the cyclopropane ring on inhibition of microbial tyramine oxidase.EBI National Institute of Diabetes and Digestive and Kidney Diseases
11881986 24 3-(1H-Pyrrol-1-yl)-2-oxazolidinones as reversible, highly potent, and selective inhibitors of monoamine oxidase type A.EBI Universit£ degli Studi di Roma La Sapienza
9258353 45 Selective inhibitors of monoamine oxidase. 4. SAR of tricyclic N-methylcarboxamides and congeners binding at the tricyclics' hydrophilic binding site.EBI Wellcome Research Laboratories
8487255 84 5-[4-(benzyloxy)phenyl]-1,3,4-oxadiazol-2(3H)-one derivatives and related analogues: new reversible, highly potent, and selective monamine oxidase type B inhibitors.EBI Universit£ Paris 7
8246228 11 Transformation of heterocyclic reversible monoamine oxidase-B inactivators into irreversible inactivators by N-methylation.EBI Northwestern University
1548678 5 5-(Aminomethyl)-3-aryldihydrofuran-2(3H)-ones, a new class of monoamine oxidase-B inactivators.EBI Northwestern University
1433183 25 Aliphatic propargylamines: potent, selective, irreversible monoamine oxidase B inhibitors.EBI University of Saskatchewan
2296014 42 Inhibition of monoamine oxidases A and B by simple isoquinoline alkaloids: racemic and optically active 1,2,3,4-tetrahydro-, 3,4-dihydro-, and fully aromatic isoquinolines.EBI University of Texas
3397993 31 Stereoisomers of allenic amines as inactivators of monoamine oxidase type B. Stereochemical probes of the active site.EBI Syntex Research
7200144 2 (+/-)-4-Aryl-4,5-dihydro-3H-1,3-benzodiazepines. 1. Synthesis and evaluation of (+/-)-4,5-dihydro-2,3-dimethyl-4-phenyl-3H-1,3-benzodiazepine and analogues as potential antidepressant agents.EBI TBA
22264472 30 Inhibition of human monoamine oxidase A and B by 5-phenoxy 8-aminoquinoline analogs.EBI University of Mississippi
22257893 22 Design and synthesis of 8-substituted benzamido-phenylxanthine derivatives as MAO-B inhibitors.EBI Wenzhou Medical College
22309913 30 Inhibition of monoamine oxidase by selected C6-substituted chromone derivatives.EBI North-West University
22225638 18 A scaffold hopping approach to identify novel monoamine oxidase B inhibitors.EBI Northeast Ohio Medical University
22078410 31 Time-dependent slowly-reversible inhibition of monoamine oxidase A by N-substituted 1,2,3,6-tetrahydropyridines.EBI West Virginia University
22017497 34 Novel reversible monoamine oxidase A inhibitors: highly potent and selective 3-(1H-pyrrol-3-yl)-2-oxazolidinones.EBI Sapienza Universit£ di Roma
21955276 60 Lysine demethylases inhibitors.EBI Kyoto Prefectural University of Medicine
22222137 13 Synthesis and biological assessment of novel 2-thiazolylhydrazones and computational analysis of their recognition by monoamine oxidase B.EBI Universit£ degli Studi Magna Gr£cia di Catanzaro
22137786 9 Hydroxycoumarins as selective MAO-B inhibitors.EBI Universit£ degli Studi di Cagliari
22071524 7 Molecular insights into human monoamine oxidase (MAO) inhibition by 1,4-naphthoquinone: evidences for menadione (vitamin K3) acting as a competitive and reversible inhibitor of MAO.EBI Federal University of Rio de Janeiro
22055712 33 Thio- and aminocaffeine analogues as inhibitors of human monoamine oxidase.EBI North-West University
22023459 42 Synthesis, biological evaluation, and molecular modeling of donepezil and N-[(5-(benzyloxy)-1-methyl-1H-indol-2-yl)methyl]-N-methylprop-2-yn-1-amine hybrids as new multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer's disease.EBI Universitat Aut£noma de Barcelona
22018876 4 Synthesis and inhibition study of monoamine oxidase, indoleamine 2,3-dioxygenase and tryptophan 2,3-dioxygenase by 3,8-substituted 5H-indeno[1,2-c]pyridazin-5-one derivatives.EBI Facult£s Universitaires Notre-Dame de Paix
22005185 25 2D MI-DRAGON: a new predictor for protein-ligands interactions and theoretic-experimental studies of US FDA drug-target network, oxoisoaporphine inhibitors for MAO-A and human parasite proteins.EBI University of Santiago de Compostela 15782
21923198 6 Synthesis of three novel fluorine-18 labeled analogues of L-deprenyl for positron emission tomography (PET) studies of monoamine oxidase B (MAO-B).EBI Karolinska Institutet
21923181 28 Synthesis and study of a series of 3-arylcoumarins as potent and selective monoamine oxidase B inhibitors.EBI University of Santiago de Compostela
21899930 37 Monoamine oxidase inhibition by selected anilide derivatives.EBI North-West University
21872365 54 Synthesis and selective human monoamine oxidase inhibition of 3-carbonyl, 3-acyl, and 3-carboxyhydrazido coumarin derivatives.EBI Universit£ degli Studi di Roma Sapienza
21777011 15 3-Acetyl-2,5-diaryl-2,3-dihydro-1,3,4-oxadiazoles: a new scaffold for the selective inhibition of monoamine oxidase B.EBI University of Cagliari
21778064 40 Inhibition of monoamine oxidase by C5-substituted phthalimide analogues.EBI North-West University
21696156 23 Chromone, a privileged scaffold for the development of monoamine oxidase inhibitors.EBI Universidade do Porto
21621312 58 8-Aryl- and alkyloxycaffeine analogues as inhibitors of monoamine oxidase.EBI North-West University
21684743 12 MAO inhibitory activity modulation: 3-Phenylcoumarins versus 3-benzoylcoumarins.EBI Universidad de Santiago de Compostela
21680183 48 Pyrazoline based MAO inhibitors: synthesis, biological evaluation and SAR studies.EBI Birla Institute of Technology
19423346 8 A new series of 3-phenylcoumarins as potent and selective MAO-B inhibitors.EBI Facultad de Farmacia
21405131 39 Homoisoflavonoids: natural scaffolds with potent and selective monoamine oxidase-B inhibition properties.EBI Universita` La Sapienza di Roma
21377879 44 Development of selective and reversible pyrazoline based MAO-B inhibitors: virtual screening, synthesis and biological evaluation.EBI Birla Institute of Technology
21316817 14 Synthesis, human monoamine oxidase inhibitory activity and molecular docking studies of 3-heteroarylcoumarin derivatives.EBI Universita degli Studi di Cagliari
21134756 90 Inhibition of monoamine oxidase by selected C5- and C6-substituted isatin analogues.EBI North-West University
21194943 9 Chromone 3-phenylcarboxamides as potent and selective MAO-B inhibitors.EBI Universidade do Porto
21183355 18 Synthesis and evaluation ofß-carboline derivatives as potential monoamine oxidase inhibitors.EBI Facult£s Universitaires Notre-Dame de la Paix
20843688 8 'Click' assembly of selective inhibitors for MAO-A.EBI Zhejiang University
20702005 17 Synthesis of new 3-aryl-4,5-dihydropyrazole-1-carbothioamide derivatives. An investigation on their ability to inhibit monoamine oxidase.EBI Dipartimento Farmaco Chimico Tecnologico
20674099 48 Inhibition of monoamine oxidase by indole and benzofuran derivatives.EBI North-West University
20715818 78 Synthesis, stereochemical separation, and biological evaluation of selective inhibitors of human MAO-B: 1-(4-arylthiazol-2-yl)-2-(3-methylcyclohexylidene)hydrazines.EBI Universita degli Studi di Roma La Sapienza
20659799 10 New halogenated 3-phenylcoumarins as potent and selective MAO-B inhibitors.EBI Universidad de Santiago de Compostela
20615716 55 Investigations on the 2-thiazolylhydrazyne scaffold: synthesis and molecular modeling of selective human monoamine oxidase inhibitors.EBI Università degli Studi di Roma La Sapienza
20382016 8 Chromone-2- and -3-carboxylic acids inhibit differently monoamine oxidases A and B.EBI Universit£ Magna Graecia di Catanzaro
19926363 29 Synthesis and inhibitory activity against human monoamine oxidase of N1-thiocarbamoyl-3,5-di(hetero)aryl-4,5-dihydro-(1H)-pyrazole derivatives.EBI Universit£ di Roma
20045650 56 A new series of flavones, thioflavones, and flavanones as selective monoamine oxidase-B inhibitors.EBI Universit£ degli Studi di Roma La Sapienza
20117937 56 Design of novel nicotinamides as potent and selective monoamine oxidase a inhibitors.EBI Nanjing University
20093036 28 Inhibition of monoamine oxidase by 8-benzyloxycaffeine analogues.EBI North-West University
19969454 7 Proposed structural basis of interaction of piperine and related compounds with monoamine oxidases.EBI University of Cambridge
19945874 24 Towards development of selective and reversible pyrazoline based MAO-inhibitors: Synthesis, biological evaluation and docking studies.EBI Institute of Technology
19804982 1 Synthesis and in vitro evaluation of pteridine analogues as monoamine oxidase B and nitric oxide synthase inhibitors.EBI North-West University
19682910 48 Synthesis and molecular modeling of some novel hexahydroindazole derivatives as potent monoamine oxidase inhibitors.EBI Hacettepe University
19628387 6 Synthesis and evaluation of 6-methyl-3-phenylcoumarins as potent and selective MAO-B inhibitors.EBI Universidad de Santiago de Compostela
19810674 93 Discovery of a novel class of potent coumarin monoamine oxidase B inhibitors: development and biopharmacological profiling of 7-[(3-chlorobenzyl)oxy]-4-[(methylamino)methyl]-2H-chromen-2-one methanesulfonate (NW-1772) as a highly potent, selective, reversible, and orally active monoamine oxidase B EBI Universita degli Studi di Bari
19321235 22 Knowledge based identification of MAO-B selective inhibitors using pharmacophore and structure based virtual screening models.EBI GVK Biosciences Pvt. Ltd.
 1 Metabolism of the Catharanthus Alkaloids: from Streptomyces griseus to Monoamine Oxidase BEBI TBA
 52 Imino 1,2,3,4-tetrahydrocyclopent[b]indole carbamates as dual inhibitors of acetylcholinesterase and monoamine oxidaseEBI TBA
 2 Selective inactivation of monoamine oxidase B by aminoethyl 3-chlorobenzyl etherEBI TBA
19342233 12 Inhibition of monoamine oxidase by (E)-styrylisatin analogues.EBI North-West University
19091581 128 New pyrazoline bearing 4(3H)-quinazolinone inhibitors of monoamine oxidase: synthesis, biological evaluation, and structural determinants of MAO-A and MAO-B selectivity.EBI Hacettepe University
19064321 37 Ultrasound promoted synthesis of 2-imidazolines in water: a greener approach toward monoamine oxidase inhibitors.EBI Universidade Federal de Santa Maria
19053775 4 Structural and mechanistic studies of mofegiline inhibition of recombinant human monoamine oxidase B.EBI Emory University
18980841 72 Pyrazoline-based mycobactin analogues as MAO-inhibitors.EBI Institute of Technology
18951803 90 Synthesis, structure-activity relationships and molecular modeling studies of new indole inhibitors of monoamine oxidases A and B.EBI Sapienza Università di Roma
18834112 52 Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.EBI University of Santiago de Compostela 15782
18723354 12 Dual inhibition of monoamine oxidase B and antagonism of the adenosine A(2A) receptor by (E,E)-8-(4-phenylbutadien-1-yl)caffeine analogues.EBI North-West University
18666768 39 Synthesis, stereochemical identification, and selective inhibitory activity against human monoamine oxidase-B of 2-methylcyclohexylidene-(4-arylthiazol-2-yl)hydrazones.EBI Università degli Studi di Roma La Sapienza
18640844 38 Fluorinated phenylcyclopropylamines. Part 5: Effects of electron-withdrawing or -donating aryl substituents on the inhibition of monoamine oxidases A and B by 2-aryl-2-fluoro-cyclopropylamines.EBI Universität Münster
16792415 3 Quercetin as the active principle of Hypericum hircinum exerts a selective inhibitory activity against MAO-A: extraction, biological analysis, and computational study.EBI Università degli Studi di Roma La Sapienza
17824599 39 Solid-phase synthesis and insights into structure-activity relationships of safinamide analogues as potent and selective inhibitors of type B monoamine oxidase.EBI University of Bari
17521909 15 Human and rat monoamine oxidase-A are differentially inhibited by (S)-4-alkylthioamphetamine derivatives: insights from molecular modeling studies.EBI University of Santiago de Chile
16942031 4 3-[5-(4,5-dihydro-1H-imidazol-2-yl)-furan-2-yl]phenylamine (Amifuraline), a promising reversible and selective peripheral MAO-A inhibitor.EBI Università degli Studi di Camerino
16759116 8 Synthesis, structural reassignment, and biological activity of type B MAO inhibitors based on the 5H-indeno[1,2-c]pyridazin-5-one core.EBI Facultés Universitaires N.D de la Paix
16356714 16 Synthesis of 3-benzyl-2-substituted quinoxalines as novel monoamine oxidase A inhibitors.EBI University of Alexandria
16137882 10 Docking studies on monoamine oxidase-B inhibitors: estimation of inhibition constants (K(i)) of a series of experimentally tested compounds.EBI Kadir Has University
15974574 56 Design, synthesis, and biological activities of pyrrolylethanoneamine derivatives, a novel class of monoamine oxidases inhibitors.EBI Università di Roma La Sapienza
15189042 24 Novel pyridazino[4,3-b]indoles with dual inhibitory activity against Mycobacterium tuberculosis and monoamine oxidase.EBI Russian Academy of Sciences
12620068 44 Simple, potent, and selective pyrrole inhibitors of monoamine oxidase types A and B.EBI Università degli Studi di Roma La Sapienza
12540239 3 Indanylidenes. 1. Design and synthesis of (E)-2-(4,6-difluoro-1-indanylidene)acetamide, a potent, centrally acting muscle relaxant with antiinflammatory and analgesic activity.EBI GlaxoSmithKline Research and Development
12467619 12 Rational approaches towards reversible inhibition of type B monoamine oxidase. Design and evaluation of a novel 5H-Indeno[1,2-c]pyridazin-5-one derivative.EBI Facultés Universitaires Notre-Dame de la Paix
12443791 9 Inhibition of amine oxidases activity by 1-acetyl-3,5-diphenyl-4,5-dihydro-(1H)-pyrazole derivatives.EBI Università di Roma La Sapienza
12127518 23 The synthesis and biological evaluation of a novel series of antimicrobials of the oxazolidinone class.EBI Abbott Laboratories
11591508 18 Synthesis of N-propargylphenelzine and analogues as neuroprotective agents.EBI CV Technologies Inc.
10794685 42 Molecular determinants of MAO selectivity in a series of indolylmethylamine derivatives: biological activities, 3D-QSAR/CoMFA analysis, and computational simulation of ligand recognition.EBI Universitat Autònoma de Barcelona
9748356 28 Inhibition of monoamine oxidase-B by condensed pyridazines and pyrimidines: effects of lipophilicity and structure-activity relationships.EBI Université de Neuchâtel
9622553 42 Selective inhibitors of monoamine oxidase (MAO). 5. 1-Substituted phenoxathiin inhibitors containing no nitrogen that inhibit MAO A by binding it to a hydrophobic site.EBI The Wellcome Research Laboratories
9089337 3 4-substituted cubylcarbinylamines: a new class of mechanism-based monoamine oxidase B inactivators.EBI Northwestern University
8627609 51 Selective inhibitors of monoamine oxidase. 3. Structure-activity relationship of tricyclics bearing imidazoline, oxadiazole, or tetrazole groups.EBI Wellcome Research Laboratories
8510099 6 Transformation of monoamine oxidase-B primary amine substrates into time-dependent inhibitors. Tertiary amine homologues of primary amine substrates.EBI Northwestern University
8474100 8 Inactivation of monoamine oxidase B by analogues of the anticonvulsant agent milacemide (2-(n-pentylamino)acetamide).EBI Northwestern University
8027990 25 Selective inhibitors of monoamine oxidase. 2. Arylamide SAR.EBI Burroughs Wellcome Company
7562919 132 Inhibition of monoamine oxidase-B by 5H-indeno[1,2-c]pyridazines: biological activities, quantitative structure-activity relationships (QSARs) and 3D-QSARs.EBI Université de Lausanne
7490728 87 Selective and potent monoamine oxidase type B inhibitors: 2-substituted 5-aryltetrazole derivatives.EBI Université Paris 7
3260955 14 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine analogues. Inactivation of monoamine oxidase by conformationally rigid analogues of N,N-dimethylcinnamylamine.EBI Northwestern University
2783613 4 Studies on semirigid tricyclic analogues of the nigrostriatal toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.EBI University of California
2704029 44 Synthesis of some novel potent and selective catechol O-methyltransferase inhibitors.EBI Orion Corporation Ltd.
2362262 1 Vinblastine and vincristine are inhibitors of monoamine oxidase B.EBI University of Iowa
1433219 9 Synthesis of novel MPTP analogs as potential monoamine oxidase B (MAO-B) inhibitors.EBI Virginia Polytechnic Institute and State University
28460360 13 Design, synthesis and biological activity of 3-oxoamino-benzenesulfonamides as selective and reversible LSD1 inhibitors.BDB China Pharmaceutical University
28267984 35 Pyridoxine-resveratrol hybrids Mannich base derivatives as novel dual inhibitors of AChE and MAO-B with antioxidant and metal-chelating properties for the treatment of Alzheimer's disease.BDB Sichuan University
27863747 21 Symmetrical aryl linked bis-iminothiazolidinones as new chemical entities for the inhibition of monoamine oxidases: Synthesis, in vitro biological evaluation and molecular modelling analysis.BDB Quaid-i-Azam University
27666135 59 Rapid synthesis of flavone-based monoamine oxidase (MAO) inhibitors targeting two active sites using click chemistry.BDB Zhejiang University of Technology
27434226 140 Evaluation of multifunctional synthetic tetralone derivatives for treatment of Alzheimer's disease.BDB Wuhan University of Technology
27662218 29 2-Heteroarylidene-1-indanone derivatives as inhibitors of monoamine oxidase.BDB North-West University
25581511 32 The Synthesis and Evaluation of C7-Substituted a-Tetralone Derivatives as Inhibitors of Monoamine Oxidase.BDB North-West University
25346162 16 Synthesis, Biological Evaluation, and Molecular Simulation of Chalcones and Aurones as Selective MAO-B Inhibitors.BDB Pontificia Universidad Catˇlica de Chile
25346381 6 Identification of Novel Selective Lysine-Specific Demethylase 1 (LSD1) Inhibitors Using a Pharmacophore-Based Virtual Screening Combined with Docking.BDB China Pharmaceutical University
26189013 14 Development of fluorinated methoxylated chalcones as selective monoamine oxidase-B inhibitors: Synthesis, biochemistry and molecular docking studies.BDB Grace College of Pharmacy
25746740 23 The adenosine receptor affinities and monoamine oxidase B inhibitory properties of sulfanylphthalimide analogues.BDB North-West University
25506816 42 Monoamine oxidase inhibitory activity of 2-aryl-4H-chromen-4-ones.BDB Birla Institute of Technology
24797717 40 Synthesis and evaluation of novel marine bromopyrrole alkaloid-based derivatives as potential antidepressant agents.BDB University of KwaZulu-Natal
25045125 4 Methyl Yellow: A Potential Drug Scaffold for Parkinson's Disease.BDB Northeast Ohio Medial University (NEOMED), College of Pharmacy, 4209 State Route 44, Rootstown, OH 44272 (USA)
24707965 33 A Selective Phenelzine Analogue Inhibitor of Histone Demethylase LSD1.BDB Johns Hopkins University School of Medicine , Baltimore, Maryland 21205, United States
24165164 9 Beyond topoisomerase inhibition: antitumor 1,4-naphthoquinones as potential inhibitors of human monoamine oxidase.BDB Institute of Chemistry, Federal University of Rio de Janeiro, Rio de Janeiro, 21941-909, Brazil.
1610807 6 Interaction of flexible analogs of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and of N-methyl-4-phenylpyridinium with highly purified monoamine oxidase A and B.BDB University of California, San Francisco
18092818 4 Comparison of the structural properties of the active site cavities of human and rat monoamine oxidase A and B in their soluble and membrane-bound forms.BDB Emory University
23064123 30 Selected C7-substituted chromone derivatives as monoamine oxidase inhibitors.BDB North-West University
22100142 41 Monoamine oxidase inhibition by C4-substituted phthalonitriles.BDB North-West University
12721338 61 N-(4-tertiarybutylphenyl)-4-(3-chloropyridin-2-yl)tetrahydropyrazine -1(2H)-carbox-amide (BCTC), a novel, orally effective vanilloid receptor 1 antagonist with analgesic properties: I. in vitro characterization and pharmacokinetic properties.BDB Pudue Pharma Discovery Research
11750180 139 Comparative affinity of duloxetine and venlafaxine for serotonin and norepinephrine transporters in vitro and in vivo, human serotonin receptor subtypes, and other neuronal receptors.BDB Lilly Research Laboratories
11356907 15 Antiparkinsonian agent piribedil displays antagonist properties at native, rat, and cloned, human alpha(2)-adrenoceptors: cellular and functional characterization.BDB Institut de Recherches Servier
11082457 63 S18616, a highly potent, spiroimidazoline agonist at alpha(2)-adrenoceptors: I. Receptor profile, antinociceptive and hypothermic actions in comparison with dexmedetomidine and clonidine.BDB Centre de Recherches de Croissy
11082453 77 ABT-702 (4-amino-5-(3-bromophenyl)-7-(6-morpholinopyridin-3-yl)pyrido[2, 3-d]pyrimidine), a novel orally effective adenosine kinase inhibitor with analgesic and anti-inflammatory properties: I. In vitro characterization and acute antinociceptive effects in the mouse.BDB Abbott Laboratories
10445051 7 Thiazole derivatives as inhibitors of purified bovine liver mitochondrial monoamine oxidase-B: structure-activity relationships and theoretical study.BDB University of Catania
16611214 84 Synthesis and molecular modelling of novel substituted-4,5-dihydro-(1H)-pyrazole derivatives as potent and highly selective monoamine oxidase-A inhibitors.BDB Università degli Studi di Roma
20455574 9 Site-activated chelators targeting acetylcholinesterase and monoamine oxidase for Alzheimer's therapy.BDB The Weizmann Institute of Science
20081854 6 Rapid behavior-based identification of neuroactive small molecules in the zebrafish.BDB Harvard Medical School
19267475 118 Synthesis, molecular modeling, and selective inhibitory activity against human monoamine oxidases of 3-carboxamido-7-substituted coumarins.BDB Universita degli Studi di Roma La Sapienza
19378991 40 Chalcones: a valid scaffold for monoamine oxidases inhibitors.BDB Universita degli Studi di Roma La Sapienza
17915852 6 Structures of Human Monoamine Oxidase B Complexes with Selective Noncovalent Inhibitors: Safinamide and Coumarin Analogs.BDB University of Pavia
17910428 48 Synthesis and monoamine oxidase inhibitory activity of new pyridazine-, pyrimidine- and 1,2,4-triazine-containing tricyclic derivatives.BDB University of Bari
17256833 68 New pyrrole inhibitors of monoamine oxidase: synthesis, biological evaluation, and structural determinants of MAO-A and MAO-B selectivity.BDB Universita di Roma La Sapienza
15710600 29 Demonstration of isoleucine 199 as a structural determinant for the selective inhibition of human monoamine oxidase B by specific reversible inhibitors.BDB Emory University
16279769 28 Synthesis, molecular modeling studies, and selective inhibitory activity against monoamine oxidase of 1-thiocarbamoyl-3,5-diaryl-4,5-dihydro-(1H)- pyrazole derivatives.BDB Universita degli Studi di Roma La Sapienza
15027867 10 Inactivation of purified human recombinant monoamine oxidases A and B by rasagiline and its analogues.BDB Emory University
16366596 18 Binding of rasagiline-related inhibitors to human monoamine oxidases: a kinetic and crystallographic analysis.BDB University of Pavia
12431053 293 Novel dual inhibitors of AChE and MAO derived from hydroxy aminoindan and phenethylamine as potential treatment for Alzheimer's disease.BDB Teva Pharmaceutical Industries