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24 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
26899595 32 A potent and selective inhibitor targeting human and murine 12/15-LOX.EBI University of California
24924423 21 Inhibitory and mechanistic investigations of oxo-lipids with human lipoxygenase isozymes.EBI University of California
25462262 98 Development and evaluation of ST-1829 based on 5-benzylidene-2-phenylthiazolones as promising agent for anti-leukotriene therapy.EBI Goethe-University Frankfurt
24920381 77 SAR studies on curcumin's pro-inflammatory targets: discovery of prenylated pyrazolocurcuminoids as potent and selective novel inhibitors of 5-lipoxygenase.EBI University Jena
24393039 97 Synthesis and structure-activity relationship studies of 4-((2-hydroxy-3-methoxybenzyl)amino)benzenesulfonamide derivatives as potent and selective inhibitors of 12-lipoxygenase.EBI National Institutes of Health
23871907 64 Discovery and biological evaluation of novel 1,4-benzoquinone and related resorcinol derivatives that inhibit 5-lipoxygenase.EBI University of Salerno
19848434 27 Using enzyme assays to evaluate the structure and bioactivity of sponge-derived meroterpenes.EBI University of California Santa Cruz
12608855 25 Exploring sponge-derived terpenoids for their potency and selectivity against 12-human, 15-human, and 15-soybean lipoxygenases.EBI University of California Santa Cruz
17826100 18 Discovery of platelet-type 12-human lipoxygenase selective inhibitors by high-throughput screening of structurally diverse libraries.EBI University of California
12036375 25 Structure-activity relationship studies of nordihydroguaiaretic acid inhibitors toward soybean, 12-human, and 15-human lipoxygenase.EBI University of California
21868137 69 Pyrazol-3-propanoic acid derivatives as novel inhibitors of leukotriene biosynthesis in human neutrophils.EBI Gazi University
21739938 72 Discovery of potent and selective inhibitors of human platelet-type 12- lipoxygenase.EBI National Human Genome Research Institute
21319773 8 Natural compound cudraflavone B shows promising anti-inflammatory properties in vitro.EBI University of Veterinary and Pharmaceutical Sciences Brno
21044840 47 Potent and selective 5-LO inhibitor bearing benzothiophene pharmacophore: discovery of MK-5286.EBI Merck Frosst Centre for Therapeutic Research
20866075 87 Discovery of potent and selective inhibitors of human reticulocyte 15-lipoxygenase-1.EBI National Human Genome Research Institute
 19 Catechol based inhibitors of 15-lipoxygenaseEBI TBA
 21 1-Phenyl-[2H]-tetrahydropyridazin-3-one, A-53612, a selective orally active 5-lipoxygenase inhibitorEBI TBA
15332838 2 An analysis of phakellin and oroidin structures stimulated by further study of an Agelas sponge.EBI University of California
17869117 153 Structure-activity relationship studies of flavonoids as potent inhibitors of human platelet 12-hLO, reticulocyte 15-hLO-1, and prostate epithelial 15-hLO-2.EBI Universidad de Santiago de Chile
16480270 40 Novel human lipoxygenase inhibitors discovered using virtual screening with homology models.EBI University of California
15267244 40 Probing the activity differences of simple and complex brominated aryl compounds against 15-soybean, 15-human, and 12-human lipoxygenase.EBI University of California
8831760 108 5-Lipoxygenase inhibitors: synthesis and structure-activity relationships of a series of 1-aryl-2H,4H-tetrahydro-1,2,4-triazin-3-ones.EBI Abbott Laboratories
8246226 86 Substituted chromenes as potent, orally active 5-lipoxygenase inhibitors.EBI Ciba-Geigy Corporation
23663316 39 In vitro study of isoflavones and isoflavans as potent inhibitors of human 12- and 15-lipoxygenases.BDB Universidad de Santiago de Chile