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29 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
27074629 5 Identification of Potential Off-target Toxicity Liabilities of Catechol-O-methyltransferase Inhibitors by Differential Competition Capture Compound Mass Spectrometry.EBI Caprotec Bioanalytics GmbH
27133481 30 Synthesis and optimization of N-heterocyclic pyridinones as catechol-O-methyltransferase (COMT) inhibitors.EBI Merck& Co.
26745812 8 Arylpiperidines as a new class of oxidosqualene cyclase inhibitors.EBI Ludwig-Maximilians University
23583910 24 Aminopropylindenes derived from Grundmann's ketone as a novel chemotype of oxidosqualene cyclase inhibitors.EBI Ludwig-Maximilians-Universit£t M£nchen
17760433 37 Influence of conformation on GRIND-based three-dimensional quantitative structure-activity relationship (3D-QSAR).EBI Universit£ di Torino
17981368 22 GRIND-based 3D-QSAR to predict inhibitory activity for similar enzymes, OSC and SHC.EBI CASMedChem Laboratory
1501233 7 2,3-Epoxy-10-aza-10,11-dihydrosqualene, a high-energy intermediate analogue inhibitor of 2,3-oxidosqualene cyclase.EBI Istituto di Chimica Farmaceutica Applicata
22533316 10 Cytotoxic effects of combination of oxidosqualene cyclase inhibitors with atorvastatin in human cancer cells.EBI Centre Hospitalier Universitaire Vaudois (CHUV) and University of Lausanne (UNIL)
17521912 15 The biology and chemistry of hyperlipidemia.EBI Sinhgad College of Pharmacy
17027267 9 Design, synthesis, and biological evaluation of new (2E,6E)-10-(dimethylamino)-3,7-dimethyl-2,6-decadien-1-ol ethers as inhibitors of human and Trypanosoma cruzi oxidosqualene cyclase.EBI Universit£ degli Studi del Piemonte Orientale A. Avogadro
12852766 22 Synthesis and structure-activity studies of novel orally active non-terpenoic 2,3-oxidosqualene cyclase inhibitors.EBI F. Hoffmann-La Roche Ltd.
22137785 6 Inhibitors of human 2,3-oxidosqualene cyclase (OSC) discovered by virtual screening.EBI Institute of Microbial Chemistry
20728352 5 Novel pyrrole- and 1,2,3-triazole-based 2,3-oxidosqualene cyclase inhibitors.EBI Institute of Microbial Chemistry
 11 Potency and inactivation rates of analogues of an irreversible inhibitor of vertebrate oxidosqualene cyclaseEBI TBA
 4 Inhibition of oxidosqualene cyclase by substituted quinolizidinesEBI TBA
 17 Inhibition of 2,3-oxidosqualene cyclase by N-alkylpiperidinesEBI TBA
 3 2,3:18,19-dioxidosqualene: synthesis and activity as a potent inhibitor of 2,3-oxidosqualene-lanosterol cyclase in rat liver microsomesEBI TBA
19119009 75 Oxidosqualene cyclase from Saccharomyces cerevisiae, Trypanosoma cruzi, Pneumocystis carinii and Arabidopsis thaliana expressed in yeast: a model for the development of novel antiparasitic agents.EBI Università di Torino
18467104 13 Design and evaluation of a novel series of 2,3-oxidosqualene cyclase inhibitors with low systemic exposure, relationship between pharmacokinetic properties and ocular toxicity.EBI Laboratoire GlaxoSmithKline
13678402 12 Oxidosqualene cyclase inhibitors as antimicrobial agents.EBI University of Utah
12747780 56 Binding structures and potencies of oxidosqualene cyclase inhibitors with the homologous squalene-hopene cyclase.EBI Albert-Ludwigs-Universität
11514173 4 Novel 4-piperidinopyridine inhibitors of oxidosqualene cyclase-lanosterol synthase derived by consideration of inhibitor pK(a).EBI AstraZeneca
11150166 12 A novel series of 4-piperidinopyridine and 4-piperidinopyrimidine inhibitors of 2,3-oxidosqualene cyclase-lanosterol synthase.EBI AstraZeneca
10197973 4 Quinuclidine inhibitors of 2,3-oxidosqualene cyclase-lanosterol synthase: optimization from lipid profiles.EBI Zeneca Pharmaceuticals
9484504 14 29-Methylidene-2,3-oxidosqualene derivatives as stereospecific mechanism-based inhibitors of liver and yeast oxidosqualene cyclase.EBI Università di Torino
9003518 23 Synthesis and inhibition studies of sulfur-substituted squalene oxide analogues as mechanism-based inhibitors of 2,3-oxidosqualene-lanosterol cyclase.EBI Simon Fraser University
8691425 23 Structural and stereoelectronic requirements for the inhibition of mammalian 2,3-oxidosqualene cyclase by substituted isoquinoline derivatives.EBI Laboratoires Fournier SCA
2769687 23 Squalene analogues containing isopropylidene mimics as potential inhibitors of pig liver squalene epoxidase and oxidosqualene cyclase.EBI State University of New York
1404239 8 N-(1-oxododecyl)-4 alpha,10-dimethyl-8-aza-trans-decal-3 beta-ol: a potent competitive inhibitor of 2,3-oxidosqualene cyclase.EBI Marion Merrell Dow Research Institute