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10 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
24593905 16 Application of encoded library technology (ELT) to a protein-protein interaction target: discovery of a potent class of integrin lymphocyte function-associated antigen 1 (LFA-1) antagonists.EBI GlaxoSmithKline
23339734 4 Design, synthesis, and functional evaluation of leukocyte function associated antigen-1 antagonists in early and late stages of cancer development.EBI Ikerchem Ltd.
20655213 31 Discovery of tetrahydroisoquinoline (THIQ) derivatives as potent and orally bioavailable LFA-1/ICAM-1 antagonists.EBI Sunesis Pharmaceuticals, Inc.
20405922 53 Small molecule antagonist of leukocyte function associated antigen-1 (LFA-1): structure-activity relationships leading to the identification of 6-((5S,9R)-9-(4-cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]nonan-7-yl)nicotinic acid (BMS-688521).EBI Bristol-Myers Squibb Research and Development
7852999 6 Cucurbitacins, Cell Adhesion Inhibitors from Conobea scoparioidesEBI TBA
9322361 1 Four new clerodane diterpenes from the leaves of Casearia guianensis which inhibit the interaction of leukocyte function antigen 1 with intercellular adhesion molecule 1.EBI Searle Research and Development
18783948 31 Structure-activity relationship of ortho- and meta-phenol based LFA-1 ICAM inhibitors.EBI Biogen Idec Inc.
18778938 20 Design and synthesis of a series of meta aniline-based LFA-1 ICAM inhibitors.EBI Biogen Idec Inc.
11728185 55 Discovery of novel p-arylthio cinnamides as antagonists of leukocyte function-associated antigen-1/intercellular adhesion molecule-1 interaction. 4. Structure-activity relationship of substituents on the benzene ring of the cinnamide.EBI Abbott Laboratories