BindingDB logo
myBDB logout

43 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
23218776 45 Discovery of novela1-adrenoceptor ligands based on the antipsychotic sertindole suitable for labeling as PET ligands.EBI H. Lundbeck A/S
9276013 38 N-arylpiperazinyl-N'-propylamino derivatives of heteroaryl amides as functional uroselective alpha 1-adrenoceptor antagonists.EBI Roche Bioscience
12519065 243 Synthesis and structure-affinity relationship investigations of 5-heteroaryl-substituted analogues of the antipsychotic sertindole. A new class of highly selective alpha(1) adrenoceptor antagonists.EBI H. Lundbeck A/S
9135028 114 Pharmacological options in the treatment of benign prostatic hyperplasia.EBI Pfizer Central Research
9083484 84 New benzocycloalkylpiperazines, potent and selective 5-HT1A receptor ligands.EBI Cooperation Pharmaceutique Fran�aise
7912735 270 3,4-Dihydro-3-amino-2H-1-benzopyran derivatives as 5-HT1A receptor ligands and potential anxiolytic agents. 1. Synthesis and structure--activity relationship studies.EBI Universit£ d'Orl£ans
1433205 8 4-Oxospiro[benzopyran-2,4'-piperidines] as class III antiarrhythmic agents. Pharmacological studies on 3,4-dihydro-1'-[2-(benzofurazan-5-yl)- ethyl]-6-methanesulfonamidospiro[(2H)-1-benzopyran-2,4'-piperidin]-4-on e (L-691,121).EBI Merck Research Laboratories
6134835 22 Synthesis and receptor binding studies relevant to the neuroleptic activities of some 1-methyl-4-piperidylidene-9-substituted-pyrrolo[2,1-b][3]benzazepine derivatives.EBI TBA
11354357 68 Two novel and potent 3-[(o-methoxyphenyl)piperazinylethyl]-5-phenylthien.EBI Abbott Laboratories
20857909 176 Exploring the neuroleptic substituent in octoclothepin: potential ligands for positron emission tomography with subnanomolar affinity fora(1)-adrenoceptors.EBI University of Copenhagen
18378462 5 Recent advances in selective alpha1-adrenoreceptor antagonists as antihypertensive agents.EBI Sinhgad College of Pharmacy
12723959 61 Synthesis and biological evaluation of new 2-(4,5-dihydro-1H-imidazol-2-yl)-3,4-dihydro-2H-1,4-benzoxazine derivatives.EBI Université d'Orléans
9622542 119 Novel benzothiazolin-2-one and benzoxazin-3-one arylpiperazine derivatives with mixed 5HT1A/D2 affinity as potential atypical antipsychotics.EBI Institut de Chimie Pharmaceutique
8667368 42 Synthesis, absolute configuration, and biological profile of the enantiomers of trans-[2-(2,6-dimethoxyphenoxy)ethyl] [(3-p-tolyl-2,3-dihydro-1,4-benzodioxin-2-yl)methyl]amine (mephendioxan), a potent competitive alpha 1A-adrenoreceptor antagonist.EBI University of Camerino
7658428 94 Alpha- and beta-adrenoceptors: from the gene to the clinic. 1. Molecular biology and adrenoceptor subclassification.EBI SmithKline Beecham Pharmaceuticals
6139479 48 Pyridinylpiperazines, a new class of selective alpha 2-adrenoceptor antagonists.EBI TBA
6088770 13 Adrenoceptor and tetrabenazine antagonism activities of some pyridinyltetrahydropyridines.EBI TBA
2999400 8 N-(1,3,4,6,7,12b-hexahydro-2H-benzo[b]furo[2,3-a]quinolizin -2-yl)-N- methyl-2-hydroxyethane-sulfonamide: a potent and selective alpha 2-adrenoceptor antagonist.EBI TBA
2831365 32 Structure-affinity relationships of arylquinolizines at alpha-adrenoceptors.EBI Merck Sharp & Dohme Research Laboratories
17221184 55 Synthesis and in vivo evaluation of a novel 5-HT1A receptor agonist radioligand [O-methyl- 11C]2-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-4-methyl-1,2,4-triazine-3,5(2H,4H)dione in nonhuman primates.BDB Columbia University
15131245 89 SR147778 [5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-4-ethyl-N-(1-piperidinyl)-1H-pyrazole-3-carboxamide], a new potent and selective antagonist of the CB1 cannabinoid receptor: biochemical and pharmacological characterization.BDB Sanofi-Synthelabo Recherche
12232544 79 [Second generation SSRIS: human monoamine transporter binding profile of escitalopram and R-fluoxetine].BDB Emory University
11750180 141 Comparative affinity of duloxetine and venlafaxine for serotonin and norepinephrine transporters in vitro and in vivo, human serotonin receptor subtypes, and other neuronal receptors.BDB Lilly Research Laboratories
11438309 51 The in vitro pharmacological profile of prucalopride, a novel enterokinetic compound.BDB Janssen Research Foundation
11132243 125 Binding of antipsychotic drugs to human brain receptors focus on newer generation compounds.BDB Mayo Foundation for Medical Education and Research and Mayo Clinic
9454810 73 SR 144528, the first potent and selective antagonist of the CB2 cannabinoid receptor.BDB Sanofi Recherche
9400006 184 Neurotransmitter receptor and transporter binding profile of antidepressants and their metabolites.BDB Emory University
9163561 56 The putative 5-HT1A receptor antagonist DU125530 blocks the discriminative stimulus of the 5-HT1A receptor agonist flesinoxan in pigeons.BDB CNS-Pharmacology
9144661 24 BW 723C86, a 5-HT2B receptor agonist, causes hyperphagia and reduced grooming in rats.BDB SmithKline Beecham Pharmaceuticals
8887981 72 A-85380 [3-(2(S)-azetidinylmethoxy) pyridine]: in vitro pharmacological properties of a novel, high affinity alpha 4 beta 2 nicotinic acetylcholine receptor ligand.BDB Abbott Laboratories
8822531 111 Radioreceptor binding profile of the atypical antipsychotic olanzapine.BDB Lilly Research Laboratories
8788493 64 Novel discriminatory ligands for 5-HT2B receptors.BDB SmithKline Beecham Pharmaceuticals
8730737 23 Effects of the 5-HT2B receptor agonist, BW 723C86, on three rat models of anxiety.BDB SmithKline Beecham Pharmaceuticals
7921604 16 The effects of SB 204070, a highly potent and selective 5-HT4 receptor antagonist, on guinea-pig distal colon.BDB SmithKline Beecham Pharmaceuticals
7855217 139 Binding of antidepressants to human brain receptors: focus on newer generation compounds.BDB Mayo Clinic Jacksonville
7815325 65 Cloning and pharmacological characterization of human alpha-1 adrenergic receptors: sequence corrections and direct comparison with other species homologues.BDB Duke University
7518514 46 (S)-3-methyl-5-(1-methyl-2-pyrrolidinyl) isoxazole (ABT 418): a novel cholinergic ligand with cognition-enhancing and anxiolytic activities: I. In vitro characterization.BDB Abbott Laboratories
6149136 83 Antagonism by neuroleptics of neurotransmitter receptors of normal human brain in vitro.BDB Mayo Clinic and Foundation
2904784 109 Neuroleptic binding to human brain receptors: relation to clinical effects.BDB Mayo Clinic and Foundation
2885412 25 Alpha-1 adrenergic receptor binding in aortas from rat and dog: comparison of [3H]prazosin and beta-iodo-[125I]-4-hydroxyphenyl-ethyl-aminomethyl-tetralone.BDB UnWersity of Misscuri
2867217 29 Selective alpha-2 adrenoceptor blockade by SK&F 86466: in vitro characterization of receptor selectivity.BDB Smith Kline & French Laboratories
1706716 29 Molecular cloning and expression of the cDNA for the alpha 1A-adrenergic receptor. The gene for which is located on human chromosome 5.BDB Duke University
1620241 6 SDZ 205-557, a selective, surmountable antagonist for 5-HT4 receptors in the isolated guinea pig ileum.BDB SANDOZ Pharma Ltd.