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55 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
26471092 23 Molecular hybridization yields triazole bronchodilators for the treatment of COPD.EBI Pfizer
25592716 6 Insights on the role of boron containing moieties in the design of new potent and efficient agonists targeting the▀2 adrenoceptor.EBI Instituto Polit£cnico Nacional
25065493 92 The identification of 7-[(R)-2-((1S,2S)-2-benzyloxycyclopentylamino)-1-hydroxyethyl]-4-hydroxybenzothiazolone as an inhaled long-acting▀2-adrenoceptor agonist.EBI Novartis Institutes for BioMedical Research
24813741 110 Multivalent design of long-acting▀(2)-adrenoceptor agonists incorporating biarylamines.EBI Theravance, Inc.
24300734 12 Design, synthesis and evaluation of dual pharmacology▀2-adrenoceptor agonists and PDE4 inhibitors.EBI Sun Yat-sen University
22932315 28 An investigation into the structure-activity relationships associated with the systematic modification of theß(2)-adrenoceptor agonist indacaterol.EBI Novartis Institutes for BioMedical Research
22079756 219 From libraries to candidate: the discovery of new ultra long-acting dibasicß2-adrenoceptor agonists.EBI AstraZeneca
21925889 48 The discovery of long-acting saligeninß2 adrenergic receptor agonists incorporating a urea group.EBI GlaxoSmithKline Medicines Research Centre
21696967 51 The discovery of long-acting saligeninß2 adrenergic receptor agonists incorporating hydantoin or uracil rings.EBI GlaxoSmithKline Medicines Research Centre
1956038 21 Synthesis and ocular antihypertensive activity of new imidazolidine derivatives containing a beta-blocking side chain.EBI Institut de Pharmacologie (UA 589 CNRS)
2903245 47 Synthesis and beta-adrenergic antagonism of 2-(aryloxy)-1-(2-piperidyl)ethanols.EBI Universidad de Barcelona
2882026 21 Role of the (acyloxy)methyl moiety in eliciting the adrenergic beta-blocking activity of 3-(acyloxy)propanolamines.EBI TBA
2872332 105 Beta 1-selective adrenoceptor antagonists: examples of the 2-[4-[3-(substituted amino)-2-hydroxypropoxy]phenyl]imidazole class. 2.EBI TBA
3012084 7 Indole-phenol bioisosterism. Synthesis and antihypertensive activity of a pyrrolo analogue of labetalol.EBI TBA
2861288 17 New chiral and isomeric cyclopropyl ketoxime propanolamine derivatives with potent beta-adrenergic blocking properties.EBI TBA
2857200 24 An interdisciplinary approach to the design of new structures active at the beta-adrenergic receptor. Aliphatic oxime ether derivatives.EBI TBA
6148422 36 Synthesis and beta-adrenergic blocking activity of new aliphatic and alicyclic oxime ethers.EBI TBA
6134834 54 Beta 1-selective adrenoceptor antagonists: examples of the 2-[4-[3-(substituted-amino)-2-hydroxypropoxy]phenyl]imidazole class.EBI TBA
6130154 68 Ultra-short-acting beta-adrenergic receptor blocking agents. 2. (Aryloxy)propanolamines containing esters on the aryl function.EBI TBA
6130153 66 Ultra-short-acting beta-adrenergic receptor blocking agents. 1. (Aryloxy)propanolamines containing esters in the nitrogen substituent.EBI TBA
6120237 15 2-Benzodioxinylaminoethanols: a new class of beta-adrenergic blocking and antihypertensive agents.EBI TBA
6104730 47 Synthesis and beta-adrenergic blocking activity of new aliphatic oxime ethers.EBI TBA
19168263 14 Synthesis, pharmacological and in silico evaluation of 1-(4-di-hydroxy-3,5-dioxa-4-borabicyclo[4.4.0]deca-7,9,11-trien-9-yl)-2-(tert-butylamino)ethanol, a compound designed to act as a beta2 adrenoceptor agonist.EBI Instituto Polit£cnico Nacional
17845020 44 Nitric oxide donor beta2-agonists: furoxan derivatives containing the fenoterol moiety and related furazans.EBI Universit£ degli Studi di Torino
7562902 114 Alpha- and beta-adrenoceptors: from the gene to the clinic. 2. Structure-activity relationships and therapeutic applications.EBI SmithKline Beecham Pharmaceuticals
8230093 21 Conformationally restrained analogs of sympathomimetic catecholamines. Synthesis, conformational analysis, and adrenergic activity of isochroman derivatives.EBI Universit£ di Pisa
1359141 47 Synthesis and hypoglycemic activity of substituted 8-(1-piperazinyl)imidazo[1,2-a]pyrazines.EBI Merck Sharp and Dohme Research Laboratories
6126588 34 Use of (S)-(trifloxymethyl)oxirane in the synthesis of a chiral beta-adrenoceptor antagonist, (R)- and (S)-9-[[3-(tert-butylamino)-2-hydroxypropyl]oximino]fluorene.EBI TBA
22297114 20 Dualß2-adrenoceptor agonists-PDE4 inhibitors for the treatment of asthma and COPD.EBI Sun Yat-sen University
21075627 26 Inhalation by design: dual pharmacology β-2 agonists/M3 antagonists for the treatment of COPD.EBI Pfizer Inc.
21277205 26 Discovery of substituted phenyl urea derivatives as novel long-actingß2-adrenoreceptor agonists.EBI Rhône-Poulenc Rorer
20402514 34 The identification of indacaterol as an ultralong-acting inhaled beta2-adrenoceptor agonist.EBI Novartis Institutes for Biomedical Research
12873495 2 Synthesis and preliminary evaluation of (R,R)(S,S) 5-(2-(2-[4-(2-[(18)F]fluoroethoxy)phenyl]-1-methylethylamino)-1-hydroxyethyl)-benzene-1,3-diol ([(18)F]FEFE) for the in vivo visualisation and quantification of the beta2-adrenergic receptor status in lung.EBI University of Mainz
7910217 36 The [(methyloxy)imino]methyl moiety as a bioisoster of aryl. A novel class of completely aliphatic beta-adrenergic receptor antagonists.EBI Universitá di Pisa
2563296 38 A new series of tricyclic (aryloximino)propanolamines displaying very high selective beta 2-blocking properties.EBI Université de Nancy I
1672155 11 Effect of fluorine substitution on the adrenergic properties of 3-(tert-butylamino)-1-(3,4-dihydroxyphenoxy)-2-propanol.EBI National Institute of Diabetes
19337725 43 Amisulpride is a potent 5-HT7 antagonist: relevance for antidepressant actions in vivo.BDB Case Western Reserve University
16051698 5 Characterization of isoprenaline- and salmeterol-stimulated interactions between beta2-adrenoceptors and beta-arrestin 2 using beta-galactosidase complementation in C2C12 cells.BDB Institute of Cell Signaling
15131245 89 SR147778 [5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-4-ethyl-N-(1-piperidinyl)-1H-pyrazole-3-carboxamide], a new potent and selective antagonist of the CB1 cannabinoid receptor: biochemical and pharmacological characterization.BDB Sanofi-Synthelabo Recherche
14730417 62 Comparative pharmacology of human beta-adrenergic receptor subtypes--characterization of stably transfected receptors in CHO cells.BDB Universität Würzburg
12784105 53 Aripiprazole, a novel atypical antipsychotic drug with a unique and robust pharmacology.BDB Case Western Reserve University
12388666 301 Differential actions of antiparkinson agents at multiple classes of monoaminergic receptor. I. A multivariate analysis of the binding profiles of 14 drugs at 21 native and cloned human receptor subtypes.BDB Institut de Recherches Servier
11750183 29 Extended radioligand binding profile of iloperidone: a broad spectrum dopamine/serotonin/norepinephrine receptor antagonist for the management of psychotic disorders.BDB Novartis Pharma
11512051 80 The in vitro pharmacology of the beta-adrenergic receptor pet ligand (s)-fluorocarazolol reveals high affinity for cloned beta-adrenergic receptors and moderate affinity for the human 5-HT1A receptor.BDB Case Western Reserve University
11438309 51 The in vitro pharmacological profile of prucalopride, a novel enterokinetic compound.BDB Janssen Research Foundation
11356907 15 Antiparkinsonian agent piribedil displays antagonist properties at native, rat, and cloned, human alpha(2)-adrenoceptors: cellular and functional characterization.BDB Institut de Recherches Servier
11303056 2 Pharmacological characterization of KUR-1246, a selective uterine relaxant.BDB Kissei Pharmaceutical Co., Ltd.
11082457 63 S18616, a highly potent, spiroimidazoline agonist at alpha(2)-adrenoceptors: I. Receptor profile, antinociceptive and hypothermic actions in comparison with dexmedetomidine and clonidine.BDB Centre de Recherches de Croissy
9454810 73 SR 144528, the first potent and selective antagonist of the CB2 cannabinoid receptor.BDB Sanofi Recherche
9144661 24 BW 723C86, a 5-HT2B receptor agonist, causes hyperphagia and reduced grooming in rats.BDB SmithKline Beecham Pharmaceuticals
8935801 586 Risperidone compared with new and reference antipsychotic drugs: in vitro and in vivo receptor binding.BDB Janssen Research Foundation
8788493 64 Novel discriminatory ligands for 5-HT2B receptors.BDB SmithKline Beecham Pharmaceuticals
8012715 38 GR113808: a novel, selective antagonist with high affinity at the 5-HT4 receptor.BDB Glaxo Group Research Ltd.
7921604 16 The effects of SB 204070, a highly potent and selective 5-HT4 receptor antagonist, on guinea-pig distal colon.BDB SmithKline Beecham Pharmaceuticals
7915318 120 Biochemical and pharmacological characterization of high-affinity trimetoquinol analogs on guinea pig and human beta adrenergic receptor subtypes: evidence for partial agonism.BDB Ohio State University