Search by Compound Name
Compounds Sorted by Binding Targets per Compound
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 2930 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55
56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 73 74 75 76 77 79 81 84 86 89 95
96 100 108 109 120 124 130 137 143 154 156 168 186 224 240 259 276 278 284 303
304 310 315 323 339 369 370 371 372 373 374 375 376 377 378 380 381 383 384
385 386 388 389 390 391 392 393 394 395 397 398 401 403 404 406 408 418 427
429 443 447 515
Compounds Sorted Alphabetically
Compound Name (alphabetical)
Binding Targets
Enz. Inhib. Data
ITC Data
Alternate Compound Names
- 3-phosphoinositide dependent protein kinase-1
- 3C-like proteinase (3CL-PRO)
- Angiopoietin-1 receptor
- Aurora kinase A/Targeting protein for Xklp2
- Axin-1/Glycogen synthase kinase-3 beta
- Epidermal growth factor receptor
- Fibroblast growth factor receptor 1
- Mast/stem cell growth factor receptor Kit
- Mitogen-activated protein kinase 1
- Mitogen-activated protein kinase 8
- Platelet-derived growth factor receptor beta
- Protein kinase C alpha type
- Proto-oncogene tyrosine-protein kinase Src
- RAC-alpha serine/threonine-protein kinase
- Replicase polyprotein 1ab
- Serine/threonine-protein kinase B-raf
- Signal transducer and activator of transcription 3
- Tyrosine-protein kinase ABL1
- Tyrosine-protein kinase JAK2
- Tyrosine-protein kinase Lyn
- Tyrosine-protein kinase receptor FLT3
- Vascular endothelial growth factor receptor 2
27 IC50
- 5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide
- med.21724, Compound 76
- niclosamide
- 20S proteasome
- Accessory gene regulator protein A
- Aldose reductase (AR)
- Casein Kinase II
- Casein kinase II alpha/beta
- Casein kinase II subunit alpha
- Cytochrome P450 1A
- EBifunctional epoxide hydrolase 2
- Estradiol receptor beta (ERβ)
- Estrogen receptor
- Genome polyprotein
- Human rhinovirus A protease
- Leukocyte elastase
- Procathepsin L
- Proteasome subunit beta type-1/beta type-5
- Protein-tyrosine phosphatase 4A3
- Purinergic receptor P2Y12
- Serine/threonine-protein kinase pim-1
- Sialidase 2
- Tyrosine-protein kinase Lck
- beta-Hydroxyacyl-acyl carrier protein dehydratase (FtFabZ)
- beta-Hydroxyacyl-acyl carrier protein dehydratase (YpFabZ)
- 1,3,8-trihydroxy-6-methyl-9,10-dihydroanthracene-9,10-dione
- 1,3,8-trihydroxy-6-methylanthra-9,10-quinone
- CHEMBL289277
- Emodin
- med.21724, Compound 24
- 3',5'-cyclic phosphodiesterase
- Alkaline phosphatase placental-like
- Alkaline phosphatase tissue-nonspecific
- Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C
- G protein-coupled receptor GPR35
- G-protein coupled receptor 35
- Heart phosphodiesterase
- Homo sapiens phosphodiesterase 2A (PDE2A)
- Phosphodiesterase 1
- Phosphodiesterase 11A (PDE11A)
- Phosphodiesterase 2A
- Phosphodiesterase 3
- Phosphodiesterase 3A
- Phosphodiesterase 4A
- Phosphodiesterase 5A
- Phosphodiesterase 6
- Phosphodiesterase 9A
- cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
- cAMP-specific 3',5'-cyclic phosphodiesterase 4A
- cAMP-specific 3',5'-cyclic phosphodiesterase 4B
- cAMP-specific 3',5'-cyclic phosphodiesterase 4D
- cGMP-specific 3',5'-cyclic phosphodiesterase
- 3-(2-propoxyphenyl)-2,4,7,8,9-pentazabicyclo[4.3.0]nona-1,3,6-trien-5-one
- 5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one
- Tocris-0947
- ZAPRINAST
- Zaprinast
- 3',5'-cyclic phosphodiesterase
- Acetylcholinesterase
- Bile salt export pump
- Canalicular multispecific organic anion transporter 1
- Canalicular multispecific organic anion transporter 2
- DNA recombination protein RecA
- Homo sapiens phosphodiesterase 2A (PDE2A)
- Multidrug resistance-associated protein 4
- Phosphodiesterase (TcrPDEC)
- Phosphodiesterase 1
- Phosphodiesterase 3 (PDE3)
- Phosphodiesterase 3A
- Phosphodiesterase 4A
- Phosphodiesterase Type 10 (PDE10A)
- Potassium voltage-gated channel subfamily H member 2
- Reverse transcriptase
- cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
- cAMP-specific 3',5'-cyclic phosphodiesterase 4B
- cAMP-specific 3',5'-cyclic phosphodiesterase 4C
- cGMP-inhibited 3',5'-cyclic phosphodiesterase B
- cGMP-specific 3',5'-cyclic phosphodiesterase
- protein-arginine deiminase type-4
- 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-isoquinoline
- 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxyisoquinoline
- 6,7-dimethoxy-1-veratryl-isoquinoline;hydrochloride
- CHEMBL19224
- Papaverine
- 5-hydroxytryptamine receptor 1A
- 5-hydroxytryptamine receptor 2A
- 5-hydroxytryptamine receptor 6
- 5-hydroxytryptamine receptor 7
- Bile salt export pump
- Canalicular multispecific organic anion transporter 1
- Canalicular multispecific organic anion transporter 2
- D(2) dopamine receptor
- D(3) dopamine receptor
- D(4) dopamine receptor
- Dopamine receptor
- HTR6
- HTR7
- Histamine H4 receptor
- Multidrug resistance-associated protein 4
- Serotonin (5-HT) receptor
- Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
- Sodium-dependent dopamine transporter
- Sodium-dependent noradrenaline transporter
- Sodium-dependent serotonin transporter
- Sulfotransferase 1A1 (SULT1A1)
- Sulfotransferase 2A1 (SULT2A1)
- 13-chloro-10-(piperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,9,12,14-heptaene
- 2-chloro-11-piperazin-1-yldibenzo[b,f][1,4]oxazepine
- Amoxapine
- Asendin
- CHEMBL1113
- Demolox
- Acetylcholinesterase
- Aurora kinase B
- Carboxylic ester hydrolase
- Cytochrome P450 1A1
- Cytochrome P450 1B1
- Enhancer of zeste homolog 1 (EZH1)
- Fructose-1,6-bisphosphatase
- G protein-coupled receptor kinase 6
- Histone-lysine N-methyltransferase SETD7
- Histone-lysine N-methyltransferase SMYD3
- Myeloid/lymphoid or mixed-lineage leukemia (MLL)
- Neuraminidase
- Nuclear SET domain-containing protein 2 (NSD2)
- Peroxisome proliferator-activated receptor gamma
- Pyruvate kinase (PKM2)
- Receptor-type tyrosine-protein phosphatase S
- Sialidase 2
- Succinate semialdehyde dehydrogenase
- Tyrosine-protein kinase receptor FLT3
- Uridine-5'-diphosphoglucuronosyltransferase 1A1
- Xanthine dehydrogenase
- alpha-Amylase
- 5,6,7-trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one
- Scutellarein
- Scutellarein (2)
- Scutellarein (28)
- US10252984, Table 2.2
- Bromodomain-containing protein 4
- Catalytic domain 2 (zCD2)
- Cereblon/Histone deacetylase 1
- Cereblon/Histone deacetylase 6
- Class 1 histone deacetylase
- Cytochrome P450 3A
- Histone Deacetylase (pfHDAC-1)
- Histone Deacetylase 4 (HDAC4) Mutant (H976Y)
- Histone deacetylase
- Histone deacetylase (HDAC1 and HDAC2)
- Histone deacetylase 1
- Histone deacetylase 10
- Histone deacetylase 11
- Histone deacetylase 2
- Histone deacetylase 3
- Histone deacetylase 4
- Histone deacetylase 5
- Histone deacetylase 7
- Histone deacetylase 8
- Histone deacetylase 9
- Leukotriene A4 hydrolase
- Potassium voltage-gated channel subfamily H member 2
- (2E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2-enamide
- Belinosta
- Belinostat
- PXD-101
- PXD101
- ADRA1B
- ADRA2A
- ADRB2
- Adrenergic receptor alpha
- Adrenergic receptor alpha-1
- Adrenergic receptor alpha-2
- Adrenergic receptor beta
- Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor
- Alpha-1A adrenergic receptor
- Beta-1 adrenergic receptor
- Beta-2 adrenergic receptor
- Beta-2 adrenergic receptor and beta-3 adrenergic receptor
- Beta-3 adrenergic receptor
- Beta-adrenergic receptor kinase 1
- Bile salt export pump
- Bile salt export pump (BSEP)
- D(1A) dopamine receptor
- D(2) dopamine receptor
- D(3) dopamine receptor
- D(4) dopamine receptor
- Serotonin (5-HT) receptor
- adrenergic Alpha2
- 4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;hydrochloride
- 4-[1-hydroxy-2-(propan-2-ylamino)ethyl]benzene-1,2-diol
- 4-{1-hydroxy-2-[(propan-2-yl)amino]ethyl}benzene-1,2-diol, 2
- CHEMBL434
- ISOPROTERONOL
- Isoprenaline
- Isoproterenol
- Isoproterenol (-)
- Isoproterenol,(+)
- Isoproterenol-l
- Norisodrine
- Novodrin
- 5-hydroxytryptamine receptor 1A
- Adrenergic receptor beta
- Beta-1 adrenergic receptor
- Beta-2 adrenergic receptor
- Beta-3 adrenergic receptor
- Bile salt export pump
- Bile salt export pump (BSEP)
- Canalicular multispecific organic anion transporter 1
- Canalicular multispecific organic anion transporter 2
- Cytochrome P450 1A
- Cytochrome P450 2C19
- Cytochrome P450 2C9
- Cytochrome P450 2D6 (2D6)
- Cytochrome P450 2J2
- Cytochrome P450 3A
- Dipeptidyl peptidase 3
- Multidrug resistance-associated protein 4
- Neuropeptide Y receptor type 1
- Neuropeptide Y receptor type 2
- P-glycoprotein 1
- Serotonin 1B/1D receptor
- Sodium channel protein type I I alpha subunit
- (2R,3R)-2,3-dihydroxysuccinic acid;1-(isopropylamino)-3-[4-(2-methoxyethyl)phenoxy]propan-2-ol
- Betalok
- CHEMBL13
- Metoprolol
- Spesicor
- Spesikor
- metoprolol tartrate
- {2-hydroxy-3-[4-(2-methoxyethyl)phenoxy]propyl}(propan-2-yl)amine
- Alpha-ketoglutarate-dependent dioxygenase FTO
- GRIA1
- GRIA2
- GRIK1
- Glutamate racemase
- Glutamate receptor ionotropic AMPA
- Glutamate receptor ionotropic, NMDA 1
- Glutamate receptor ionotropic, kainate 2
- Glutamate-Kainate 7
- Grik5
- Ionotropic glutamate receptor kainate 2/5
- Metabotropic glutamate receptor
- Metabotropic glutamate receptor 1
- Metabotropic glutamate receptor 2
- Metabotropic glutamate receptor 3
- Metabotropic glutamate receptor 4 (mGlu4)
- Metabotropic glutamate receptor 4 (mGluR4)
- Metabotropic glutamate receptor 5
- Metabotropic glutamate receptor 6
- Metabotropic glutamate receptor 6 (mGlu6)
- Metabotropic glutamate receptor 7 (mGlu7)
- Metabotropic glutamate receptor 8 (mGlu8)
- (2R)-2-aminopentanedioic acid
- CHEMBL76232
- D-Glu
- D-Glutamate
- D-[14C]Glu
- 5-hydroxytryptamine receptor 1A
- 5-hydroxytryptamine receptor 1B
- 5-hydroxytryptamine receptor 1D
- 5-hydroxytryptamine receptor 2A
- 5-hydroxytryptamine receptor 2B
- 5-hydroxytryptamine receptor 2C
- 5-hydroxytryptamine receptor 6
- 5-hydroxytryptamine receptor 7
- Acetylcholinesterase
- HTR1D
- HTR2B
- HTR6
- HTR7
- Melatonin receptor
- Serotonin (5-HT) receptor
- Serotonin 1 (5-HT1) receptor
- Serotonin 1B/1D receptor
- Serotonin 1d (5-HT1d) receptor
- Serotonin 2 (5-HT2) receptor
- Serotonin receptor 2a and 2b (5HT2A and 5HT2B)
- Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
- Sphingosine 1-phosphate receptor 3
- 2-(5-methoxy-1H-indol-3-yl)-N,N-dimethyl-ethanamine
- 2-(5-methoxy-1H-indol-3-yl)-N,N-dimethylethanamine
- 2-(5-methoxy-1H-indol-3-yl)ethyl-dimethyl-amine
- 3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE
- CHEMBL7257
- MLS000069438
- Methoxydimethyltryptamines
- SMR000059066
- cid_1832
- Axin-1/Glycogen synthase kinase-3 beta
- Beta-chymotrypsin
- Glycogen Synthase Kinase-3, beta
- Homeodomain-interacting protein kinase 1
- Malate dehydrogenase
- Mitogen-activated protein kinase kinase kinase 8
- Mitogen-activated protein kinase kinase kinase kinase 1
- NAD-Dependent Deacetylase Sirtuin-1
- NAD-dependent deacetylase HST2
- NAD-dependent deacetylase sirtuin 2
- NAD-dependent protein deacetylase sirtuin-3 (SIRT3)
- Protein Kinase C
- Protein kinase C alpha type
- Ribosomal protein S6 kinase (P70S6K)
- Ribosomal protein S6 kinase alpha 5
- Ribosomal protein S6 kinase alpha-3
- Serine/threonine-protein kinase PIM
- Serine/threonine-protein kinase TBK1
- Serine/threonine-protein kinase VRK1
- Serine/threonine-protein kinase VRK2
- Serine/threonine-protein kinase pim-1
- cAMP-Dependent Protein Kinase (PKA)
1 ΔG°
- 3-[1-[3-(Amidinothio)propyl]-3-indolyl]-4-(1-methyl-3-indolyl)-1H-pyrrole-2,5-dione Methanesulfonate
- BIM-9
- Bisindolylmaleimide 11b
- Bisindolylmaleimide IX
- CHEMBL6291
- ROCHE screening, 57
- Ro 31-8220
- Ro31-8220
- [(3-{3-[4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl]-1H-indol-1-yl}propyl)sulfanyl]methanimidamide
- 1,3-beta-glucan synthase component GLS2
- Axin-1/Glycogen synthase kinase-3 beta
- Carbonic anhydrase
- Carbonic anhydrase 1
- Carbonic anhydrase 2
- Carbonic anhydrases; II & IX
- Cereblon/BCR/ABL
- Cytochrome P450 2C9
- Cytochrome P450 3A
- DNA-PK/Ku70/Ku85
- Dual-specificity tyrosine-phosphorylation regulated kinase 2
- Focal adhesion kinase 1/vascular endothelial growth factor receptor 3
- Glycogen synthase kinase-3
- Mast/stem cell growth factor receptor Kit
- Mitogen-activated protein kinase kinase kinase 9
- Serine-protein kinase ATM
- Serine/threonine-protein kinase ATR
- Tyrosine-protein kinase JAK2
- Tyrosine-protein kinase Mer
- Tyrosine-protein kinase SYK
- Tyrosine-protein kinase receptor FLT3
- p110α/p85α
- 3-[3-[4-[dideuterio(methylamino)methyl]phenyl]isoxazol-5-yl]-5-(4-isopropylsulfonylphenyl)pyrazin-2-amine
- BDBM50226746
- US10208027, Compound II-1
- US10208027, Compound II-2
- US10208027, Compound II-3
- US10208027, Compound II-4
- US10479784, Compound IIA-7
- US10822331, Cmpd II-4
- GRIA1
- GRIA2
- GRIA3
- GRIK1
- GRIK4
- Glutamate kainate
- Glutamate receptor 1
- Glutamate receptor ionotropic AMPA
- Glutamate receptor ionotropic kainate
- Glutamate receptor ionotropic kainate 4
- Glutamate receptor ionotropic kainate 5
- Glutamate receptor ionotropic, AMPA 2
- Glutamate receptor ionotropic, AMPA 4
- Glutamate receptor ionotropic, NMDA 1
- Glutamate receptor ionotropic, kainate
- Glutamate receptor ionotropic, kainate 1
- Glutamate receptor ionotropic, kainate 2
- Glutamate-Kainate 7
- Grik5
- Ionotropic glutamate receptor kainate 2/5
- Metabotropic glutamate receptor 5
- Metabotropic glutamate receptor 6
- (2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic acid
- (3S,4R)-3-(carboxymethyl)-4-(prop-1-en-2-yl)-L-proline
- CHEMBL275040
- Digenin
- Digensaeure
- Helminal
- Kainate
- Kainsaeure
- L-alpha-kainic acid
- alpha-Kainic acid
- digenic acid
- kainic acid
- ATP-binding cassette sub-family G member 2
- Adrenergic Alpha
- Bile salt export pump
- Bile salt export pump (BSEP)
- Calcium channel
- Calcium channel (Type L)
- Canalicular multispecific organic anion transporter 1
- Canalicular multispecific organic anion transporter 2
- Cav1.3/Cav beta3/Cav alpha2delta complex
- Cytochrome P450 2J2
- Cytochrome P450 3A
- Multidrug resistance protein 1/Multidrug resistance associated protein 1
- Multidrug resistance-associated protein 4
- P-glycoprotein 1
- Potassium voltage-gated channel subfamily H member 2
- Sodium channel protein type 7 subunit alpha
- Sodium channel protein type I I alpha subunit
- Voltage-dependent L-type calcium channel subunit alpha-1C
- Voltage-dependent L-type calcium channel subunit alpha-1S
- Voltage-gated L-type calcium channel
- Voltage-gated L-type calcium channel alpha-1C subunit
- Voltage-gated potassium channel subfamily A member 1/beta-1
- (+)-cis-Diltiazem
- (2S,3S)-5-(2-(dimethylamino)ethyl)-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-3-yl acetate
- 5-(2-dimethylamino-ethyl)-2-(4-methoxy-phenyl)-4-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]thiazepin-3-yl ester(Diltiazem)Acetic acid
- 8-Chloro-1-methyl-6-phenyl-4H-2,3,5,10b-tetraaza-benzo[e]azulene
- Acetic acid (2S,3S)-5-(2-dimethylamino-ethyl)-2-(4-methoxy-phenyl)-4-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]thiazepin-3-yl ester
- Acetic acid (S)-5-(2-dimethylamino-ethyl)-2-(4-methoxy-phenyl)-4-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]thiazepin-3-yl ester
- Acetic acid 5-(2-dimethylamino-ethyl)-2-(4-methoxy-phenyl)-4-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]thiazepin-3-yl ester
- Acetic acid 5-(2-dimethylamino-ethyl)-2-(4-methoxy-phenyl)-4-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]thiazepin-3-yl ester (diltiazem)
- Acetic acid 5-(2-dimethylamino-ethyl)-2-(4-methoxy-phenyl)-4-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]thiazepin-3-yl ester(cis-(+)-Diltiazem)
- Acetic acid 5-(2-dimethylamino-ethyl)-2-(4-methoxy-phenyl)-4-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]thiazepin-3-yl ester; hydrochloride
- CHEMBL23
- Cardizem
- DILTIAZEM
- Dilt-CD
- Diltzac
- Teczem
- Tiamate
- Tiazac
- cis-Acetic acid 5-(2-dimethylamino-ethyl)-2-(4-methoxy-phenyl)-4-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]thiazepin-3-yl ester
- diltiazem;Acetic acid 5-(2-dimethylamino-ethyl)-2-(4-methoxy-phenyl)-4-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]thiazepin-3-yl ester
- 5-hydroxytryptamine receptor 1A
- 5-hydroxytryptamine receptor 2A
- 5-hydroxytryptamine receptor 2C
- Alpha-1A adrenergic receptor
- Alpha-2A adrenergic receptor
- D(2) dopamine receptor
- Dopamine transporter
- HTR1D
- HTR2C
- Histamine H1 receptor
- Muscarinic acetylcholine receptor M1
- Muscarinic acetylcholine receptor M2
- Muscarinic acetylcholine receptor M3
- Muscarinic acetylcholine receptor M4
- Muscarinic acetylcholine receptor M5
- Norepinephrine transporter
- SLC6A3
- Serotonin (5-HT) receptor
- Serotonin 1B/1D receptor
- Sodium-dependent dopamine transporter
- Sodium-dependent noradrenaline transporter
- Sodium-dependent serotonin transporter
27 Ki
- (3R,4S)-3-(4-Methoxy-phenoxymethyl)-1-methyl-4-phenyl-piperidine
- 3-(4-Methoxy-phenoxymethyl)-1-methyl-4-phenyl-piperidine(femoxetine)
- CHEMBL94739
- Femoxetine
- Aldehyde oxidase
- Arachidonate 5-lipoxygenase
- Bile salt export pump
- Butyrylcholinesterase (BuChE)
- Calcium channel
- Cyclooxygenase
- Cystic fibrosis transmembrane conductance regulator
- DNA-directed RNA polymerase subunit beta'
- Glutathione reductase (GR)
- Histidine-rich protein
- P-glycoprotein 1
- Phospholipase A2 group 1B
- Phospholipase A2 group IIA
- Phospholipase A2, acidic
- Phospholipase A2, major isoenzyme
- Phospholipase A2, membrane associated
- Prion protein
- Prostaglandin G/H synthase (cyclooxygenase)
- Replicase polyprotein 1ab
- Riboflavin-binding protein
- Sodium channel protein type I I alpha subunit
- Trypanothione reductase
- 6-chloro-2-methoxy-9-acridinyl(4-diethylamino-1-methylbutyl)amine
- 6-chloro-N-(5-(diethylamino)pentan-2-yl)-2-methoxyacridin-9-amine
- CHEMBL7568
- N'-(6-chloro-2-methoxy-acridin-9-yl)-N,N-diethyl-pentane-1,4-diamine
- N*4*-(6-Chloro-2-methoxy-acridin-9-yl)-N*1*,N*1*-diethyl-pentane-1,4-diamine
- N*4*-(6-Chloro-2-methoxy-acridin-9-yl)-N*1*,N*1*-diethyl-pentane-1,4-diamine (Mepacrine)
- N*4*-(6-Chloro-2-methoxy-acridin-9-yl)-N*1*,N*1*-diethyl-pentane-1,4-diamine ; (mepacrine)
- N-(4-Hydroxy-phenyl)-acetamide
- cid_237
- quinacrine
- Adrenaline alpha1
- Adrenaline alpha2
- Alpha-1A adrenergic receptor
- Bile salt export pump
- Bile salt export pump (BSEP)
- Canalicular multispecific organic anion transporter 1
- Canalicular multispecific organic anion transporter 2
- Cytochrome P450 2J2
- Histamine H1 receptor
- Histamine H3 receptor
- Histamine H4 receptor
- Multidrug resistance-associated protein 4
- Muscarinic acetylcholine receptor M1
- Muscarinic acetylcholine receptor M2
- Muscarinic acetylcholine receptor M3
- Muscarinic acetylcholine receptor M4
- Muscarinic acetylcholine receptor M5
- Phosphoehtnaolamine Methyltransferases 2 (PMT2)
- Potassium voltage-gated channel subfamily H member 2
- Sodium channel protein type 5 subunit alpha
- Sodium channel protein type I I alpha subunit
- Voltage-dependent L-type calcium channel subunit alpha-1C
- (2-Benzhydryloxy-ethyl)-dimethyl-amine
- 2-(benzhydryloxy)-N,N-dimethylethanamine
- 2-(diphenylmethoxy)-N,N-dimethylethanamine
- Antitussive
- Beldin
- Belix
- Benadryl
- Benylin
- CHEMBL657
- DIMENHYDRINATE
- DIPHENHYDRAMINE
- Dibenil
- Diphen
- Hydramine
- N-[2-(BENZHYDRYLOXY)ETHYL]-N,N-DIMETHYLAMINE
- Silphen
- US9138431, DIPHENHYDRAMINE (Benadryl)
- US9333199, DIPHENHYDRAMINE (Benadryl)
- 5-hydroxytryptamine receptor 1A
- 5-hydroxytryptamine receptor 2A
- ADRA1A
- ADRA1B
- Adrenergic alpha1B
- Adrenergic receptor
- Adrenergic receptor alpha
- Adrenergic receptor alpha-2
- Alpha adrenergic receptor (1a and 1d)
- Alpha adrenergic receptor 1A and 1B
- Alpha adrenergic receptor 1A and 1D
- Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor
- Alpha-1A adrenergic receptor
- Alpha-1D adrenergic receptor
- Cerebral cortex alpha adrenergic receptor
- D(2) dopamine receptor
- D(3) dopamine receptor
- Dopamine receptor
- HTR2C
- Serotonin (5-HT) receptor
- Serotonin 1B/1D receptor
- Serotonin 2 (5-HT2) receptor
- 8-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-8-azaspiro[4.5]decane-7,9-dione
- 8-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-8-azaspiro[4.5]decane-7,9-dione
- 8-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-8-aza-spiro[4.5]decane-7,9-dione
- 8-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-8-aza-spiro[4.5]decane-7,9-dione(BMY-7378)
- BMY 7378
- BMY-7378
- CHEMBL1256934
- CHEMBL13647
- CHEMBL543741
- Bile salt export pump
- Canalicular multispecific organic anion transporter 1
- Canalicular multispecific organic anion transporter 2
- Cytochrome CYP26A1
- Cytochrome P450 26B1
- Multidrug resistance-associated protein 4
- NR2B Channel Blocker
- Nuclear receptor subfamily 4 group A member 2/Retinoic acid receptor RXR-alpha
- Oxysterols receptor LXR-alpha
- Oxysterols receptor LXR-beta
- Retinoic acid receptor RXR-alpha
- Retinoic acid receptor RXR-alpha/Retinoic acid receptor beta
- Retinoic acid receptor RXR-alpha/gamma
- Retinoic acid receptor alpha/Retinoid X receptor alpha
- Retinoid X receptor
- Retinoid X receptor alpha
- Retinoid X receptor alpha (F313I/L436F)
- Retinoid X receptor alpha (F313I/L436V)
- Retinoid X receptor beta
- Retinoid X receptor gamma
- Retinoid X receptor gamma/retinoic acid receptor alpha
- Retinoid receptor
- 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl]benzoic acid
- BEXAROTENE
- CHEMBL1023
- p-(1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthyl)vinyl)benzoic acid
- 5-hydroxytryptamine receptor 2A
- 5-hydroxytryptamine receptor 2B
- 5-hydroxytryptamine receptor 2C
- 5-hydroxytryptamine receptor 2C (5HT2C)
- 5-hydroxytryptamine receptor 7
- Adenosine receptor A1
- Alpha-1A adrenergic receptor
- Cytochrome P450 19A1
- Cytochrome P450 1A
- Cytochrome P450 2C9
- Cytochrome P450 2D6 (2D6)
- Cytochrome P450 3A
- D(2) dopamine receptor
- D(3) dopamine receptor
- D(4) dopamine receptor
- Gamma-aminobutyric acid receptor subunit alpha-1
- Histamine H1 receptor
- Neuronal acetylcholine receptor protein alpha-7 subunit
- Serotonin (5-HT) receptor
- Serotonin 1d (5-HT1d) receptor
- Serotonin receptor 2a and 2b (5HT2A and 5HT2B)
- Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
- 5-Methyl-3,5-dihydro-2H-pyrrolo[2,3-f]indole-1-carboxylic acid pyridin-3-ylamide
- CHEMBL297784
- SB 206553
- SB-206553
- ATP-binding cassette sub-family G member 2
- Cytochrome P450 1A
- Cytochrome P450 2A6
- Cytochrome P450 2B6
- Cytochrome P450 2C19
- Cytochrome P450 2C8
- Cytochrome P450 2C9
- Cytochrome P450 2D6 (2D6)
- Cytochrome P450 3A
- Human immunodeficiency virus type 1 reverse transcriptase
- Human immunodeficiency virus type 2 integrase
- Integrase
- Multidrug resistance-associated protein 2 (MRP2)
- P-glycoprotein 1
- Sigma intracellular receptor 2
- Sigma non-opioid intracellular receptor 1
- Sigma-2 receptor
- Solute carrier family 22 member 2
- Solute carrier organic anion transporter family member 1B1 (OATP1B1)
- Solute carrier organic anion transporter family member 1B3 (OATP1B3)
- Uridine-5'-diphosphoglucuronosyltransferase 1A1
- Vesicular acetylcholine transporter
- CHEBI:76010
- DOLUTEGRAVIR
- Dolutegravir
- GSK1349572
- S-349572
- ATPase family AAA domain-containing protein 2
- ATPase family AAA domain-containing protein 2B
- Bromodomain adjacent to zinc finger domain protein 2A
- Bromodomain adjacent to zinc finger domain protein 2B
- Bromodomain and PHD finger-containing protein 3
- Bromodomain testis-specific protein
- Bromodomain-containing protein 1
- Bromodomain-containing protein 2
- Bromodomain-containing protein 3
- Bromodomain-containing protein 4
- Bromodomain-containing protein 7
- Bromodomain-containing protein 9
- Cat eye syndrome critical region protein 2
- Histone acetyltransferase KAT2A
- Histone acetyltransferase PCAF
- Nucleosome-remodeling factor subunit BPTF
- Peregrin
- Protein polybromo-1
- Transcription activator BRG1
- Transcription initiation factor TFIID subunit 1
- Transcription initiation factor TFIID subunit 1-like
- Tyrosine-protein kinase BAZ1B
- CHEMBL3590408
- 5-hydroxytryptamine receptor 1A
- 5-hydroxytryptamine receptor 1B
- 5-hydroxytryptamine receptor 1D
- 5-hydroxytryptamine receptor 2A
- 5-hydroxytryptamine receptor 2C
- 5-hydroxytryptamine receptor 5A
- 5-hydroxytryptamine receptor 6
- 5-hydroxytryptamine receptor 7
- D(1A) dopamine receptor
- D(2) dopamine receptor
- D(3) dopamine receptor
- Delta-type opioid receptor
- Dopamine D1B
- Dopamine receptor
- Histamine H1 receptor
- Kappa-type opioid receptor
- Mu-type opioid receptor
- Muscarinic acetylcholine receptor M2
- Muscarinic acetylcholine receptor M3
- Muscarinic acetylcholine receptor M4
- Muscarinic acetylcholine receptor M5
- Serotonin (5-HT) receptor
23 Ki
- 3-[4-(2-Fluoro-phenyl)-piperazin-1-ylmethyl]-1H-pyrrolo[2,3-b]pyridine
- CHEMBL282424
- 5-hydroxytryptamine receptor 1A
- 5-hydroxytryptamine receptor 1B
- 5-hydroxytryptamine receptor 1D
- 5-hydroxytryptamine receptor 2A
- 5-hydroxytryptamine receptor 2C
- 5-hydroxytryptamine receptor 5A
- 5-hydroxytryptamine receptor 6
- 5-hydroxytryptamine receptor 7
- D(1A) dopamine receptor
- D(2) dopamine receptor
- D(3) dopamine receptor
- Delta-type opioid receptor
- Dopamine D1B
- Dopamine receptor
- Histamine H1 receptor
- Kappa-type opioid receptor
- Mu-type opioid receptor
- Muscarinic acetylcholine receptor M2
- Muscarinic acetylcholine receptor M3
- Muscarinic acetylcholine receptor M4
- Muscarinic acetylcholine receptor M5
- Serotonin (5-HT) receptor
23 Ki
- 3-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-1H-pyrrolo[2,3-b]pyridine
- CHEMBL435949
- 5-hydroxytryptamine receptor 1A
- 5-hydroxytryptamine receptor 1B
- 5-hydroxytryptamine receptor 1D
- 5-hydroxytryptamine receptor 2A
- 5-hydroxytryptamine receptor 2C
- 5-hydroxytryptamine receptor 5A
- 5-hydroxytryptamine receptor 6
- 5-hydroxytryptamine receptor 7
- D(1A) dopamine receptor
- D(2) dopamine receptor
- D(3) dopamine receptor
- Delta-type opioid receptor
- Dopamine D1B
- Dopamine receptor
- Histamine H1 receptor
- Kappa-type opioid receptor
- Mu-type opioid receptor
- Muscarinic acetylcholine receptor M2
- Muscarinic acetylcholine receptor M3
- Muscarinic acetylcholine receptor M4
- Muscarinic acetylcholine receptor M5
- Serotonin (5-HT) receptor
23 Ki
- 3-[4-(4-Methylsulfanyl-phenyl)-piperazin-1-ylmethyl]-1H-pyrrolo[2,3-b]pyridine
- CHEMBL28651
- 5-hydroxytryptamine receptor 1A
- 5-hydroxytryptamine receptor 1B
- 5-hydroxytryptamine receptor 1D
- 5-hydroxytryptamine receptor 2A
- 5-hydroxytryptamine receptor 2C
- 5-hydroxytryptamine receptor 5A
- 5-hydroxytryptamine receptor 6
- 5-hydroxytryptamine receptor 7
- D(1A) dopamine receptor
- D(2) dopamine receptor
- D(3) dopamine receptor
- Delta-type opioid receptor
- Dopamine D1B
- Dopamine receptor
- Histamine H1 receptor
- Kappa-type opioid receptor
- Mu-type opioid receptor
- Muscarinic acetylcholine receptor M2
- Muscarinic acetylcholine receptor M3
- Muscarinic acetylcholine receptor M4
- Muscarinic acetylcholine receptor M5
- Serotonin (5-HT) receptor
23 Ki
- 3-[4-(4-Fluoro-phenyl)-piperazin-1-ylmethyl]-1H-pyrrolo[2,3-b]pyridine
- CHEMBL28997
- Alpha trans-inducing protein (VP16)
- Bile salt export pump
- Canalicular multispecific organic anion transporter 1
- Canalicular multispecific organic anion transporter 2
- Cytochrome P450 3A
- DNA topoisomerase I (Topo I)
- DNA topoisomerase II
- Human immunodeficiency virus type 1 integrase
- Multidrug resistance protein 1/Multidrug resistance associated protein 1
- Multidrug resistance-associated protein 2 (MRP2)
- Multidrug resistance-associated protein 4
- Nuclear receptor coactivator 1
- P-glycoprotein (P-gp)
- P-glycoprotein 1
- P-glycoprotein 1 and 3 (MDR1a/MDR1b)
- Regulatory protein E2
- Serum paraoxonase/arylesterase 1
- Similar to alpha-tubulin isoform 1
- Solute carrier organic anion transporter family member 1B3 (OATP1B3)
- Topoisomerase I/II
- Topoisomerase II alpha (HuTopoIIα)
- nuclear receptor coactivator 3 isoform a
- (-)-etoposide
- (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside
- 4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylidene-beta-D-glucopyranoside)
- 4-demethylepipodophyllotoxin beta-D-ethylideneglucoside
- 9-((4,6-O-Ethylidine-beta-D-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,4-dimethyloxyphenyl)furo(3',4'':6,7)naptho-(2,3-d)-1,3-dioxol-6(5aH)-one
- CHEMBL44657
- Etoposide (ET)
- TRANS-ETOPOSIDE
- VP-16
- etoposide
- 72 kDa type IV collagenase
- Cereblon/Histone deacetylase 6
- Collagenase 3
- Disintegrin and metalloproteinase domain-containing protein 17
- Histone deacetylase 1
- Histone deacetylase 10
- Histone deacetylase 11
- Histone deacetylase 2
- Histone deacetylase 3
- Histone deacetylase 4
- Histone deacetylase 5
- Histone deacetylase 7
- Histone deacetylase 8
- Histone deacetylase 9
- Interstitial collagenase
- Matrix metalloproteinase 10
- Matrix metalloproteinase-12 (MMP12)
- Matrix metalloproteinase-14 (MMP14)
- Matrix metalloproteinase-7 (MMP7)
- Matrix metalloproteinase-9
- Neutrophil collagenase
- Stromelysin-1
22 IC50
- CHEMBL3394285
- 12-Lipoxygenase (12-LOX)
- Angiopoietin-1 receptor
- Arachidonate 15-lipoxygenase
- Aurora kinase A/Targeting protein for Xklp2
- Aurora kinase B
- Cyclin-Dependent Kinase 4 (CDK4)
- Ephrin type-B receptor 4
- Epidermal growth factor receptor
- Focal adhesion kinase 1
- Hepatocyte growth factor receptor
- Insulin receptor
- Insulin-like growth factor I receptor
- Mitogen-activated protein kinase kinase kinase 8
- NUAK family SNF1-like kinase 1
- Platelet-derived growth factor receptor beta
- Proto-oncogene tyrosine-protein kinase Src
- Receptor tyrosine-protein kinase erbB-2
- Ryanodine receptor 1
- Serine/threonine-protein kinase PLK4
- Tyrosine-protein kinase receptor FLT3
- Vascular endothelial growth factor receptor 2
- Vascular endothelial growth factor receptor 3
- Bastadin-7
- Bastadins 7
- CHEMBL360190
- bastadin 7
- polybrominated diphenyl ether derivative
- Angiopoietin-1 receptor
- Inhibitor of nuclear factor kappa-B kinase subunit alpha
- Inhibitor of nuclear factor kappa-B kinase subunit beta
- Interleukin-1 receptor-associated kinase 4
- MAP kinase p38
- MAP kinase-activated protein kinase 2
- Mitogen-activated protein kinase kinase kinase 8
- Non-receptor tyrosine-protein kinase TYK2
- Protein kinase C (PKC)
- Proto-oncogene tyrosine-protein kinase Src
- Tyrosine-protein kinase Fgr
- Tyrosine-protein kinase Fyn
- Tyrosine-protein kinase HCK
- Tyrosine-protein kinase ITK/TSK
- Tyrosine-protein kinase JAK3
- Tyrosine-protein kinase LCK
- Tyrosine-protein kinase Lck
- Tyrosine-protein kinase Lyn
- Tyrosine-protein kinase SYK
- Tyrosine-protein kinase ZAP-70
- Vascular endothelial growth factor receptor 2
- cAMP-dependent protein kinase (PKA)
- A-770041
- CHEMBL197603
- N-(4-(1-(4-(4-acetylpiperazin-1-yl)cyclohexyl)-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-2-methoxyphenyl)-1-methyl-1H-indole-2-carboxamide
- N-(4-{1-[4-(4-ACETYLPIPERAZIN-1-YL)-TRANS-CYCLOHEXYL]-4-AMINO-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL}-2-METHOXYPHENYL)-1-METHYL-1H-INDOLE-2-CARBOXAMIDE
- 1,3-beta-glucan synthase component GLS2
- ALK tyrosine kinase receptor
- Epidermal growth factor receptor
- Fibroblast growth factor receptor 1
- Hepatocyte growth factor receptor
- Insulin-like growth factor I receptor
- Leukocyte tyrosine kinase receptor
- Macrophage-stimulating protein receptor
- Mast/stem cell growth factor receptor Kit
- Platelet-derived growth factor receptor alpha
- Platelet-derived growth factor receptor beta
- Proto-oncogene tyrosine-protein kinase ROS
- Proto-oncogene tyrosine-protein kinase Src
- Proto-oncogene tyrosine-protein kinase receptor Ret
- Receptor protein-tyrosine kinase erbB-4
- Receptor tyrosine-protein kinase erbB-2
- Tyrosine-protein kinase ABL1
- Tyrosine-protein kinase receptor FLT3
- Tyrosine-protein kinase receptor TYRO3
- Tyrosine-protein kinase receptor UFO
- Vascular endothelial growth factor receptor 1
- Vascular endothelial growth factor receptor 2
32 IC50
- CHEMBL3735648
- 1,3-beta-glucan synthase component GLS2
- Choline kinase alpha
- Choline/ethanolamine kinase
- Cytochrome P450 1A
- Cytochrome P450 2C19
- Cytochrome P450 2C9
- Cytochrome P450 2D6
- Cytochrome P450 3A
- Diacylglycerol kinase beta
- Diacylglycerol kinase gamma
- Diacylglycerol kinase zeta
- PI3-kinase class I
- Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR
- Phosphatidylinositol 3-kinase regulatory subunit beta
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
- Phosphatidylinositol 4-kinase beta
- Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
- Sphingosine kinase 1 (SPHK1)
- Sphingosine kinase types 2 (SphK2)
27 IC50
- CHEMBL4060768
- CDK1/Cyclin E
- CDK2/Cyclin O
- CDK3/E
- CDK4/Cyclin D3
- CDK6/CycD3
- CDK6/cyclin D1
- CDK9/Cyclin K
- Cyclin-Dependent Kinase 1 (CDK1)
- Cyclin-Dependent Kinase 2 (CDK2)
- Cyclin-Dependent Kinase 5 (CDK5)
- Cyclin-Dependent Kinase 7 (CDK7)
- Cyclin-Dependent Kinase 9 (CDK9)
- Cyclin-dependent kinase 1
- Cyclin-dependent kinase 4
- Cyclin-dependent kinase 6
- Cyclin-dependent kinase 9
- Cytochrome P450 1A
- Cytochrome P450 2C19
- Cytochrome P450 2C9
- Cytochrome P450 2D6
- Cytochrome P450 3A
- Melanin-concentrating hormone receptor 2/HERG
23 IC50
- CHEMBL4079206
- Cyclin-dependent kinase 1
- Cyclin-dependent kinase 2
- Cyclin-dependent kinase 4
- Epidermal growth factor receptor
- Fibroblast growth factor receptor 1
- Fibroblast growth factor receptor 2
- Fibroblast growth factor receptor 3
- Fibroblast growth factor receptor 4
- Insulin receptor
- Insulin-like growth factor I receptor
- Mitogen-activated protein kinase kinase kinase 11
- Platelet-derived growth factor receptor alpha
- Platelet-derived growth factor receptor beta
- Proto-oncogene tyrosine-protein kinase Src
- Receptor tyrosine-protein kinase erbB-2
- Serine/threonine-protein kinase PLK1
- Tyrosine-protein kinase Lck
- Tyrosine-protein kinase Lyn
- Tyrosine-protein kinase receptor FLT3
- Vascular endothelial growth factor receptor 1
- Vascular endothelial growth factor receptor 2
- Vascular endothelial growth factor receptor 3
- (Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acetyl]amino}-phenylamino)-methylene]-2-oxo-2,3-dihydro-1H-indole-6-carboxylicAcid Methyl Ester
- CHEMBL502835
- methyl (3Z)-3-{[(4-{methyl[(4-methylpiperazin-1-yl)acetyl]amino}phenyl)amino](phenyl)methylidene}-2-oxo-2,3-dihydro-1H-indole-6-carboxylate
- Aurora kinase B
- CDK2/Cyclin A/Cyclin A1
- Casein kinase I
- Cyclin-Dependent Kinase 1 (CDK1)
- MAP kinase-activated protein kinase 2
- Mitogen-activated protein kinase 1
- Mitogen-activated protein kinase 14
- Mitogen-activated protein kinase kinase kinase kinase 2
- PKC alpha and beta-2
- Platelet-derived growth factor receptor alpha
- Protein kinase C (PKC)
- Protein kinase C delta type
- Protein kinase C theta type
- Protein kinase C, epsilon
- Protein kinase C, eta
- Proto-oncogene tyrosine-protein kinase Src
- Rho-associated protein kinase 1
- Ribosomal protein S6 kinase alpha 1
- Serine/threonine-protein kinase Chk1/2
- Tyrosine-protein kinase Fyn
- Tyrosine-protein kinase HCK
- Tyrosine-protein kinase Lyn
22 IC50
- 4-(4-methyl-1H-indol-5-ylamino)-5-(3-(4-methylpiperazin-1-ylsulfonyl)styryl)nicotinonitrile
- CHEMBL1080994
- Aurora kinase B
- CDK2/Cyclin A/Cyclin A1
- Casein kinase I
- Cyclin-Dependent Kinase 1 (CDK1)
- MAP kinase-activated protein kinase 2
- Mitogen-activated protein kinase 1
- Mitogen-activated protein kinase 14
- Mitogen-activated protein kinase kinase kinase kinase 2
- PKC alpha and beta-2
- Platelet-derived growth factor receptor alpha
- Protein kinase C (PKC)
- Protein kinase C delta type
- Protein kinase C theta type
- Protein kinase C, epsilon
- Protein kinase C, eta
- Proto-oncogene tyrosine-protein kinase Src
- Rho-associated protein kinase 1
- Ribosomal protein S6 kinase alpha 1
- Serine/threonine-protein kinase Chk1/2
- Tyrosine-protein kinase Fyn
- Tyrosine-protein kinase HCK
- Tyrosine-protein kinase Lyn
22 IC50
- 6-methyl-4-(4-methyl-1H-indol-5-ylamino)-5-(3-(4-methylpiperazin-1-ylsulfonyl)styryl)nicotinonitrile
- CHEMBL1080995
- Angiopoietin-1 receptor
- Aurora kinase B
- Cyclin-dependent-like kinase 5
- Ephrin type-B receptor 4
- Epidermal growth factor receptor
- Insulin-like growth factor I receptor
- Macrophage colony-stimulating factor 1 receptor (CSF1R)
- Mast/stem cell growth factor receptor Kit
- Mitogen-activated protein kinase 14
- Mitogen-activated protein kinase 3
- Mitogen-activated protein kinase 9
- Proto-oncogene tyrosine-protein kinase Src
- RAC-alpha serine/threonine-protein kinase
- Ribosomal protein S6 kinase (P70S6K)
- Serine/threonine-protein kinase PLK1
- Tyrosine-protein kinase ABL1
- Tyrosine-protein kinase BTK
- Tyrosine-protein kinase JAK2
- Tyrosine-protein kinase JAK3
- Tyrosine-protein kinase Lck
- Tyrosine-protein kinase ZAP-70
- Vascular endothelial growth factor receptor 2
- CHEMBL1242977
- N-(3-Methyl-4-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yloxy)phenyl)-3-(trifluoromethyl)benzamide
- 10 kDa chaperonin
- 60 kDa chaperonin
- Bile salt export pump
- Canalicular multispecific organic anion transporter 1
- Canalicular multispecific organic anion transporter 2
- Chitinase B
- Cytochrome P450 1B1
- Cytochrome P450 2J2
- Cytochrome P450 3A
- HSP60/HSP10
- Low molecular weight phosphotyrosine protein phosphatase
- Motilin receptor
- Multidrug and toxin extrusion protein 1
- Multidrug resistance-associated protein 4
- Organic anion-transporting polypeptide 1D1 (Oatp1d1)
- P-glycoprotein (P-gp)
- P-glycoprotein 1
- P-glycoprotein 1 and 3 (MDR1a/MDR1b)
- Potassium voltage-gated channel subfamily H member 2
- Serum albumin
- Sterol 14α-demethylase (CYP51)
- Thiosulfate sulfurtransferase
- CHEMBL532
- E-MYCIN E
- ERYTHROMYCIN
- ERYTHROMYCIN ETHYLSUCCINATE
- Erycette
- Erymax
- Erythromycin A
- Erythromycin C
- Ilotycin
- T-Stat
- 5'-AMP-activated protein kinase catalytic subunit alpha-1
- Aurora kinase A/Targeting protein for Xklp2
- Cyclin-Dependent Kinase 1 (CDK1)
- Dual specificity mitogen-activated protein kinase kinase 1
- Epidermal growth factor receptor
- Fibroblast growth factor receptor 1
- Focal adhesion kinase 1
- Hepatocyte growth factor receptor
- Insulin receptor
- Insulin-like growth factor I receptor
- Mast/stem cell growth factor receptor Kit
- Platelet-derived growth factor receptor alpha
- Platelet-derived growth factor receptor beta
- Receptor protein-tyrosine kinase erbB-4
- Receptor tyrosine-protein kinase erbB-2
- Serine/threonine-protein kinase 11
- Serine/threonine-protein kinase pim-1
- Tyrosine-protein kinase ABL1
- Tyrosine-protein kinase JAK2
- Tyrosine-protein kinase SYK
- Tyrosine-protein kinase receptor FLT3
- Vascular endothelial growth factor receptor 1
22 IC50
- CHEMBL2035810
- ALK tyrosine kinase receptor
- Angiopoietin-1 receptor
- EGFR
- Ephrin type-A receptor 2 (EPHA2)
- Epidermal growth factor receptor
- Epithelial discoidin domain-containing receptor 1
- Hepatocyte growth factor receptor
- Macrophage-stimulating protein receptor
- Mast/stem cell growth factor receptor Kit
- Mitogen-activated protein kinase kinase kinase 11
- Platelet-derived growth factor receptor
- Platelet-derived growth factor receptor alpha
- Platelet-derived growth factor receptor alpha (PDGFRα)
- Platelet-derived growth factor receptor beta
- Proto-oncogene c-Kit (c-Kit)
- Proto-oncogene tyrosine-protein kinase ROS
- Smoothened homolog
- Tyrosine-protein kinase receptor FLT3
- Tyrosine-protein kinase receptor UFO
- Vascular endothelial growth factor receptor 1
- Vascular endothelial growth factor receptor 2
- Vascular endothelial growth factor receptor 3
- FORETINIB
- US10464902, Foretinib
- US10882853, Compound For-Oxide
- Axin-1/Glycogen synthase kinase-3 beta
- CDK2/Cyclin A/Cyclin A1
- Casein kinase I isoform delta
- Epidermal growth factor receptor
- Hepatocyte growth factor receptor
- Inhibitor of nuclear factor kappa-B kinase subunit beta
- Inhibitor of nuclear factor kappa-B kinase subunit epsilon
- Insulin receptor
- MAP kinase-activated protein kinase 2
- Mitogen-activated protein kinase 1
- Protein kinase C (PKC)
- Proto-oncogene tyrosine-protein kinase Src
- RAC-alpha serine/threonine-protein kinase
- Serine/threonine-protein kinase CHK2
- Serine/threonine-protein kinase Chk1/2
- Serine/threonine-protein kinase Sgk1
- Serine/threonine-protein kinase pim-2
- Tyrosine-protein kinase ABL1
- Tyrosine-protein kinase Mer
- Tyrosine-protein kinase receptor TYRO3
- Tyrosine-protein kinase receptor UFO
- [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial
22 IC50
- CHEMBL2312290
- 1,3-beta-glucan synthase component GLS2
- Activin receptor type-1
- Activin receptor type-1B
- Activin receptor-like kinase 3 (ALK-3)
- Alpha-2A adrenergic receptor
- Bone morphogenetic protein receptor type-1B (BMPR1B) aa 168-495
- Cannabinoid receptor 1
- Cytochrome P450
- Cytochrome P450 1A
- Cytochrome P450 2B6
- Cytochrome P450 2C19
- Cytochrome P450 2C8
- Epithelial discoidin domain-containing receptor 1
- Mixed lineage kinase 7
- Serine/threonine protein kinase NLK
- Serine/threonine-protein kinase SIK2
- Serine/threonine-protein kinase receptor R3
- TGF-beta receptor type-1
- TRAF2- and NCK-interacting kinase
- Tyrosine-protein kinase BRK
- VHL/BCR-ABL1
- Voltage-gated potassium channel subunit Kv7.1/Misshapen-like kinase 1
36 IC50
- CHEMBL4517408
- Axin-1/Glycogen synthase kinase-3 beta
- CDK2/Cyclin A/Cyclin A1
- CDK2/Cyclin E/G1/S-specific cyclin E2
- Cdc2
- Cell division control protein 28
- Cyclin B/Cyclin-Dependent Kinase 1 (CDK1)/G2/mitotic-specific cyclin B2/G2/mitotic-specific cyclin B3
- Cyclin-Dependent Kinase 1 (CDK1)
- Cyclin-Dependent Kinase 4 (CDK4)
- Cyclin-dependent kinase 1
- Cyclin-dependent kinase 2
- Cyclin-dependent kinase 4
- Cyclin-dependent-like kinase 5
- Insulin receptor
- Mitogen-activated protein kinase 3
- PKC alpha and beta-2
- Protein kinase C (PKC)
- Protein kinase C alpha type
- Protein kinase C delta type
- Protein kinase C, epsilon
- Protein kinase C, eta
- Protein kinase C, gamma
- cAMP-dependent protein kinase (PKA)
27 IC50
- 2-chloro-4-[(2-{[(1R)-1-(hydroxymethyl)-2-methylpropyl]amino}-9-isopropyl-9H-purin-6-yl)amino]benzoic acid
- 2-chloro-4-[(2-{[(2R)-1-hydroxy-3-methylbutan-2-yl]amino}-9-(propan-2-yl)-9H-purin-6-yl)amino]benzoic acid
- CHEMBL23254
- Purvalanol B
- Bfl-1
- Carbonic Anhydrase III
- Carbonic Anhydrase VA
- Carbonic Anhydrase VB
- Carbonic Anhydrase XIII
- Carbonic Anhydrase XIV
- Carbonic anhydrase 1
- Carbonic anhydrase 12
- Carbonic anhydrase 15
- Carbonic anhydrase 2
- Carbonic anhydrase 4
- Carbonic anhydrase 6 (CA-VI)
- Carbonic anhydrase 7
- Carbonic anhydrase 9
- Caspase-2
- DNA topoisomerase II
- Glutamate [NMDA] receptor subunit epsilon 2/zeta 1
- Glutamate delta 2
- Glutamate receptor ionotropic, NMDA 1
- Glutamate receptor ionotropic, NMDA 2B
- Phosphodiesterase 1
- ubiquitin-conjugating enzyme E2 N
- 3-aminopropyl-[4-(3-aminopropylamino)butyl]amine;hydrochloride
- CHEMBL23194
- MLS002472980
- N,N''-bis(3-aminopropyl)butane-1,4-diamine;hydrochloride
- N,N''-bis(3-azanylpropyl)butane-1,4-diamine;hydrochloride
- N,N'-bis(3-aminopropyl)butane-1,4-diamine
- SMR001397086
- Spermine
- cid_5351186
- spermidine 3HCl
- 5-HT3A Serotonin Receptor
- 5-hydroxytryptamine receptor 1A
- 5-hydroxytryptamine receptor 2A
- 5-hydroxytryptamine receptor 2B
- 5-hydroxytryptamine receptor 2C
- 5-hydroxytryptamine receptor 2C (5HT2C)
- ADRA2A
- ADRB1
- Adrenergic receptor alpha-2
- Alpha adrenergic receptor 1A and 1B
- Beta-2 adrenergic receptor
- GRIA3
- Gamma-aminobutyric acid receptor subunit alpha-1
- Glutamate receptor ionotropic, NMDA 1
- HTR7
- Kappa-type opioid receptor
- Mu-type opioid receptor
- Muscarinic acetylcholine receptor M1
- Muscarinic acetylcholine receptor M2
- Muscarinic acetylcholine receptor M3
- Neurokinin 1 receptor
- Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
- N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)-1-oxopentyl]-2,4-dimethoxyphenyl]-4-(trifluoromethyl)benzenesulfonamide
- RS-102221