BDBM50170647 CHEMBL626::Methyl-naphthalen-1-ylmethyl-((E)-3-phenyl-allyl)-amine::Methyl-naphthalen-1-ylmethyl-(3-phenyl-allyl)-amine::NAFTIFINE::Naftin

SMILES CN(C\C=C\c1ccccc1)Cc1cccc2ccccc12

InChI Key InChIKey=OZGNYLLQHRPOBR-DHZHZOJOSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50170647   

TargetC-8 sterol isomerase ERG2(Saccharomyces cerevisiae)
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50170647(CHEMBL626 | Methyl-naphthalen-1-ylmethyl-((E)-3-ph...)
Affinity DataKi:  310nMAssay Description:Affinity for ERG2 of Sacchromyces cerevisiae using [3H]ifenprodil or (+)-[3H]pentazocine radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50170647(CHEMBL626 | Methyl-naphthalen-1-ylmethyl-((E)-3-ph...)
Affinity DataKi:  880nMAssay Description:Affinity for sigma receptor type 1 of guinea pig using [3H]ifenprodil or (+)-[3H]pentazocine radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50170647(CHEMBL626 | Methyl-naphthalen-1-ylmethyl-((E)-3-ph...)
Affinity DataKi:  1.50E+3nMAssay Description:Affinity for human EMP expressed in ERG2 deficient strain of Sacchromyces cerevisiae using [3H]ifenprodil or (+)-[3H]pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming)(Staphylococcus aureus (strain Newman))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50170647(CHEMBL626 | Methyl-naphthalen-1-ylmethyl-((E)-3-ph...)
Affinity DataIC50:  296nMAssay Description:Inhibition of diapophytoene desaturase in Staphylococcus aureus Newman assessed as reduction in staphyloxanthin pigment formationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene epoxidase ERG1(Candida albicans (strain SC5314 / ATCC MYA-2876) (...)
Liaocheng University

Curated by ChEMBL
LigandPNGBDBM50170647(CHEMBL626 | Methyl-naphthalen-1-ylmethyl-((E)-3-ph...)
Affinity DataIC50:  317nMAssay Description:Inhibition of SE in Candida albicans ATCC SC5314 incubated for 30 mins using squalene as substrate in presence of NADPH by spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming)(Staphylococcus aureus (strain Newman))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50170647(CHEMBL626 | Methyl-naphthalen-1-ylmethyl-((E)-3-ph...)
Affinity DataIC50:  8.83E+3nMAssay Description:Inhibition of Staphylococcus aureus Newman 6His-tagged CrtN expressed in Escherichia coli BL21(DE3) using diapophytoene as substrate assessed as pigm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed