BDBM50318458 4-bromo-N-(2,2,2-trichloro-1-(4-chlorophenylthio)ethyl)benzamide::AMG-7160::CHEMBL1086588

SMILES Clc1ccc(SC(NC(=O)c2ccc(Br)cc2)C(Cl)(Cl)Cl)cc1

InChI Key InChIKey=APLQHKFABMHWHP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50318458   

LigandPNGBDBM50318458(AMG-7160 | 4-bromo-N-(2,2,2-trichloro-1-(4-chlorop...)
Affinity DataIC50: 28nMAssay Description:Antagonist activity at human TRPA1 channel assessed as inhibition of noxious cold-induced receptor activationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50318458(AMG-7160 | 4-bromo-N-(2,2,2-trichloro-1-(4-chlorop...)
Affinity DataIC50: 51nMAssay Description:Antagonist activity at human TRPA1 channel assessed as inhibition of allyl isothiocyanate-induced intracellular calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50318458(AMG-7160 | 4-bromo-N-(2,2,2-trichloro-1-(4-chlorop...)
Affinity DataIC50: 252nMAssay Description:Antagonist activity at human TRPA1 channel assessed as inhibition of allyl isothiocyanate-induced currentsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed