BDBM100416 US9695132, I-214

SMILES COc1cc(OC)c(Cl)c(N2Cc3cnc(NC4COCC4NC(=O)C=C)nc3N(Cc3c[nH]cn3)C2=O)c1Cl

InChI Key InChIKey=FBOWOWASFAKWKW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 100416   

TargetFibroblast growth factor receptor 4(Human)
Celgene Car

US Patent
LigandPNGBDBM100416(US9695132, I-214)
Affinity DataIC50: 100nMpH: 7.5Assay Description:Omnia Assay Protocol for Potency Assessment Against FGFR 4 Enzyme. a) [FGFR4-WT]=10 nM, [ATP]=300 uM, [Y10-Sox]=10 uM (ATP KMapp 300 uM): A 10x stock...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2018
Entry Details
US Patent