BDBM100568 US8501732, I-128

SMILES COC(=O)c1c(CNC(=O)C2CCN(CC2)C(=O)OC(C)(C)C)c(=O)c2ccc(Cl)cc2n1-c1ccccc1

InChI Key InChIKey=VYHPGKDOPUXYOK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 100568   

TargetMitogen-activated protein kinase 8(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM100568(US8501732, I-128)
Affinity DataIC50: 35nMAssay Description:In vitro JNK1 assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2013
Entry Details
US Patent