BDBM10253 2-(4-Fluoro-benzyl)isoquinoline-1,3,4-trione::2-[(4-fluorophenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-1,3,4-trione::Isoquinoline-1,3,4-trione 2f

SMILES Fc1ccc(CN2C(=O)C(=O)c3ccccc3C2=O)cc1

InChI Key InChIKey=XFTAXSAPJPVWNZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10253   

TargetCaspase-3(Human)
Shanghai Institutes For Biological Sciences

LigandPNGBDBM10253(2-(4-Fluoro-benzyl)isoquinoline-1,3,4-trione | 2-[...)
Affinity DataIC50: 630nMpH: 7.5 T: 2°CAssay Description:The rate of chromogenic substrate hydrolysis was monitored by the change of absorbance at 405 nm for 3 min. Compounds were tested in duplicate. The I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2006
Entry Details Article
PubMed