BDBM102588 US8536172, I-37

SMILES CC(=O)N1CCN(CC1)c1cccc2n(ccc12)-c1ccnc(NC2CCCCC2)n1

InChI Key InChIKey=BZOFRQXHTNQEIJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 102588   

TargetMitogen-activated protein kinase 8(Human)
Roche Palo Alto

US Patent
LigandPNGBDBM102588(US8536172, I-37)
Affinity DataIC50: 48.4nMpH: 7.5Assay Description:JNK activity was measured by phosphorylation of GST-ATF2 (19-96) with [gamma-33P] ATP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2013
Entry Details
US Patent

TargetMitogen-activated protein kinase 8(Human)
Roche Palo Alto

US Patent
LigandPNGBDBM102588(US8536172, I-37)
Affinity DataIC50: 4.03E+3nMpH: 7.5Assay Description:JNK activity was measured by phosphorylation of GST-ATF2 (19-96) with [gamma-33P] ATP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2013
Entry Details
US Patent