BDBM11415 2-(2-Methoxyethyl)-3-[[bis(2-methoxyethyl)amino]methyl]-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide hydrochloride::2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide 22::3-{[bis(2-methoxyethyl)amino]methyl}-2-(2-methoxyethyl)-1,1-dioxo-2H-1,7,2-thieno[3,2-e][1,2]thiazine-6-sulfonamide hydrochloride::Compound 17h2

SMILES COCCN(CCOC)CC1=Cc2cc(sc2S(=O)(=O)N1CCOC)S(N)(=O)=O

InChI Key InChIKey=XFXOAMVXWCAOLA-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 11415   

TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11415(Compound 17h2 | 3-{[bis(2-methoxyethyl)amino]methy...)
Affinity DataKi:  0.210nMAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Alcon Research

LigandPNGBDBM11415(Compound 17h2 | 3-{[bis(2-methoxyethyl)amino]methy...)
Affinity DataIC50: 4.41nMAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed