BDBM11706 (2S)-Cyanopyrrolidine analogue 18j::3-({2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl}amino)-N-[(4-nitrophenyl)methyl]propanamide::3-[2-(2-Cyano-(S)-pyrrolidin-1-yl)-2-oxoethylamino]-N-(4-nitrobenzyl)propionamide

SMILES [O-][N+](=O)c1ccc(CNC(=O)CCNCC(=O)N2CCC[C@H]2C#N)cc1

InChI Key InChIKey=MRMUOZCXACZMBV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 11706   

TargetDipeptidyl peptidase 4(Human)
National Health Research Institutes

LigandPNGBDBM11706(3-[2-(2-Cyano-(S)-pyrrolidin-1-yl)-2-oxoethylamino...)
Affinity DataIC50: 317nMpH: 8.0 T: 2°CAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
National Health Research Institutes

LigandPNGBDBM11706(3-[2-(2-Cyano-(S)-pyrrolidin-1-yl)-2-oxoethylamino...)
Affinity DataIC50: 2.39E+3nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
National Health Research Institutes

LigandPNGBDBM11706(3-[2-(2-Cyano-(S)-pyrrolidin-1-yl)-2-oxoethylamino...)
Affinity DataIC50: 3.60E+4nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2006
Entry Details Article
PubMed