BDBM12513 (2S)-2-[(3S)-3-[(6-chloronaphthalene-2-)sulfonamido]-2-oxopyrrolidin-1-yl]-N-ethyl-N-(pyridin-4-ylmethyl)propanamide::P4 alanylamide pyrrolidin-2-one 24

SMILES CCN(Cc1ccncc1)C(=O)[C@H](C)N1CC[C@H](NS(=O)(=O)c2ccc3cc(Cl)ccc3c2)C1=O

InChI Key InChIKey=XHNRETTXQLOZNQ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 12513   

TargetCoagulation factor X(Human)
Glaxosmithkline

LigandPNGBDBM12513((2S)-2-[(3S)-3-[(6-chloronaphthalene-2-)sulfonamid...)
Affinity DataKi:  27nM ΔG°:  -10.3kcal/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrate. The hydrolysis rates of chromogenic substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2006
Entry Details Article
PubMed