BDBM15871 5,6-dichloro-9-hydroxy-1-methyl-3-(trifluoromethyl)-1H,4H,9H-pyrazolo[3,4-b]quinolin-4-one::9-hydroxy pyrazoloquinolinone 9a

SMILES Cn1nc(c2c1n(O)c1ccc(Cl)c(Cl)c1c2=O)C(F)(F)F

InChI Key InChIKey=RVGHXTBOLXQJEJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15871   

TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandPNGBDBM15871(5,6-dichloro-9-hydroxy-1-methyl-3-(trifluoromethyl...)
Affinity DataIC50: 1.00E+4nMpH: 7.2 T: 2°CAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2007
Entry Details Article
PubMed