BDBM15889 3-tert-butyl-6-chloro-9-hydroxy-1-methyl-1H,4H,9H-pyrazolo[3,4-b]quinolin-4-one::9-hydroxy pyrazoloquinolinone 7e

SMILES Cn1nc(c2c1n(O)c1ccc(Cl)cc1c2=O)C(C)(C)C

InChI Key InChIKey=AXTSKSFFQDLFDZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15889   

TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandPNGBDBM15889(3-tert-butyl-6-chloro-9-hydroxy-1-methyl-1H,4H,9H-...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2007
Entry Details Article
PubMed