BDBM15944 4-Amino-6-[2-(2,5-dimethoxyphenyl)ethylamino]-2-ethoxynicotinonitrile::4-amino-6-{[2-(2,5-dimethoxyphenyl)ethyl]amino}-2-ethoxypyridine-3-carbonitrile::Aminopyridine-Based Inhibitor 10

SMILES CCOc1nc(NCCc2cc(OC)ccc2OC)cc(N)c1C#N

InChI Key InChIKey=FQKRCTGZAXBPRF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 15944   

TargetMitogen-activated protein kinase 9(Human)
Abbott Laboratories

LigandPNGBDBM15944(4-amino-6-{[2-(2,5-dimethoxyphenyl)ethyl]amino}-2-...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandPNGBDBM15944(4-amino-6-{[2-(2,5-dimethoxyphenyl)ethyl]amino}-2-...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed