BDBM16665 2-oxo-N-[(4-sulfamoylphenyl)methyl]-2H-chromene-3-carboxamide::4-(Coumarin-3-yl-carboxamidomethyl)benzenesulfonamide::aromatic sulfonamide compound 30

SMILES NS(=O)(=O)c1ccc(CNC(=O)c2cc3ccccc3oc2=O)cc1

InChI Key InChIKey=XFYVUTWRZYOMNA-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 16665   

TargetCarbonic anhydrase 2(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM16665(2-oxo-N-[(4-sulfamoylphenyl)methyl]-2H-chromene-3-...)
Affinity DataKi:  12nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2007
Entry Details Article
PubMed
TargetCarbonic anhydrase 5A, mitochondrial(Mouse)
Universita Degli Studi Di Firenze

LigandPNGBDBM16665(2-oxo-N-[(4-sulfamoylphenyl)methyl]-2H-chromene-3-...)
Affinity DataKi:  20nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2007
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM16665(2-oxo-N-[(4-sulfamoylphenyl)methyl]-2H-chromene-3-...)
Affinity DataKi:  64nMAssay Description:Inhibition of human recombinant CA12 assessed as inhibition constant incubated for 45 mins by phenol red dye based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCarbonic anhydrase 1(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM16665(2-oxo-N-[(4-sulfamoylphenyl)methyl]-2H-chromene-3-...)
Affinity DataKi:  69nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2007
Entry Details Article
PubMed
TargetCarbonic anhydrase 5B, mitochondrial(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM16665(2-oxo-N-[(4-sulfamoylphenyl)methyl]-2H-chromene-3-...)
Affinity DataKi:  71nMAssay Description:Inhibition of human recombinant CA5B assessed as inhibition constant incubated for 45 mins by phenol red dye based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCarbonic anhydrase 5A, mitochondrial(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM16665(2-oxo-N-[(4-sulfamoylphenyl)methyl]-2H-chromene-3-...)
Affinity DataKi:  71nMAssay Description:Inhibition of human recombinant CA5A assessed as inhibition constant incubated for 45 mins by phenol red dye based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM16665(2-oxo-N-[(4-sulfamoylphenyl)methyl]-2H-chromene-3-...)
Affinity DataKi:  142nMAssay Description:Inhibition of human recombinant CA2 assessed as inhibition constant incubated for 45 mins by phenol red dye based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCarbonic anhydrase 7(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM16665(2-oxo-N-[(4-sulfamoylphenyl)methyl]-2H-chromene-3-...)
Affinity DataKi:  158nMAssay Description:Inhibition of human recombinant CA7 assessed as inhibition constant incubated for 45 mins by phenol red dye based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCarbonic anhydrase 4(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM16665(2-oxo-N-[(4-sulfamoylphenyl)methyl]-2H-chromene-3-...)
Affinity DataKi:  244nMAssay Description:Inhibition of human recombinant CA4 assessed as inhibition constant incubated for 45 mins by phenol red dye based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCarbonic anhydrase 1(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM16665(2-oxo-N-[(4-sulfamoylphenyl)methyl]-2H-chromene-3-...)
Affinity DataKi:  1.94E+3nMAssay Description:Inhibition of human recombinant CA1 assessed as inhibition constant incubated for 45 mins by phenol red dye based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed