BDBM20581 N-{4-[(6-{4-[(1R)-1-(4-fluorophenyl)ethyl]piperazin-1-yl}pyrimidin-4-yl)oxy]-1,3-benzothiazol-2-yl}acetamide::Piperazinylpyrimidine analogue, 16p

SMILES C[C@@H](N1CCN(CC1)c1cc(Oc2cccc3sc(NC(C)=O)nc23)ncn1)c1ccc(F)cc1

InChI Key InChIKey=QUHZTEMPQQZPNB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 20581   

LigandPNGBDBM20581(N-{4-[(6-{4-[(1R)-1-(4-fluorophenyl)ethyl]piperazi...)
Affinity DataIC50: 2nMAssay Description:TRPV1 activities were monitored as a function of cellular uptake of radioactive calcium (45Ca2+). The test compounds were preincubated with TRPV1 exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2008
Entry Details Article
PubMed
LigandPNGBDBM20581(N-{4-[(6-{4-[(1R)-1-(4-fluorophenyl)ethyl]piperazi...)
Affinity DataIC50: 3.70nMpH: 7.4 T: 2°CAssay Description:TRPV1 activities were monitored as a function of cellular uptake of radioactive calcium (45Ca2+). The test compounds were preincubated with TRPV1 exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2008
Entry Details Article
PubMed
LigandPNGBDBM20581(N-{4-[(6-{4-[(1R)-1-(4-fluorophenyl)ethyl]piperazi...)
Affinity DataIC50: 3.70nMAssay Description:Antagonist activity at rat TRPV1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed