BDBM211017 US9247759, 4-52

SMILES Cc1cc(C(=O)Nc2cnn(Cc3c(C)noc3C)c2)n(C)n1

InChI Key InChIKey=CIAQNGLFZRDTCL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 211017   

TargetTaste receptor type 2 member 8(Human)
Firmenich

Curated by ChEMBL
LigandPNGBDBM211017(US9247759, 4-52)
Affinity DataIC50: 1.80E+4nMAssay Description:Antagonist activity at recombinant human TAS2R8 stably expressed in cells co-expressing Galpha16gust44 assessed as inhibition of andrographolide-indu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTaste receptor type 2 member 8(Human)
Firmenich

Curated by ChEMBL
LigandPNGBDBM211017(US9247759, 4-52)
Affinity DataIC50: 1.81E+4nMAssay Description:In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2017
Entry Details
US Patent