BDBM21498 Dihydropyrrolopyrazole, 8::methyl 4-[2-(6-methylpyridin-2-yl)-4H,5H,6H-pyrrolo[1,2-a]pyrazol-3-yl]quinoline-6-carboxylate

SMILES COC(=O)c1ccc2nccc(-c3c4CCCn4nc3-c3cccc(C)n3)c2c1

InChI Key InChIKey=PYUBAZVUCQOMKF-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 21498   

LigandPNGBDBM21498(methyl 4-[2-(6-methylpyridin-2-yl)-4H,5H,6H-pyrrol...)
Affinity DataIC50: 526nM EC50:  403nMpH: 7.5 T: 2°CAssay Description:The kinase activity was assayed by the autophosphorylation reaction of ALK5 (T204D) in the presence of 4 uM ATP and [33P]-gamma-ATP. After incubation...More data for this Ligand-Target Pair
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Date in BDB:
4/18/2008
Entry Details Article
PubMed