BDBM22194 2-(4-{2-[bis(4-fluorophenyl)methoxy]ethyl}piperazin-1-yl)-1-phenylethan-1-one::GBR 12935 Analogue, 23

SMILES Fc1ccc(cc1)C(OCCN1CCN(CC(=O)c2ccccc2)CC1)c1ccc(F)cc1

InChI Key InChIKey=PLTVEFQGFXRXRM-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 22194   

TargetSodium-dependent dopamine transporter(Rat)
National Taiwan University

LigandPNGBDBM22194(2-(4-{2-[bis(4-fluorophenyl)methoxy]ethyl}piperazi...)
Affinity DataKi:  54nMAssay Description:The assay was initiated by the addition of membranes to binding buffer containing test compound, blocker, and radioligand. The samples were incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2008
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Taiwan University

LigandPNGBDBM22194(2-(4-{2-[bis(4-fluorophenyl)methoxy]ethyl}piperazi...)
Affinity DataKi:  88nMAssay Description:The assay was initiated by the addition of membranes to binding buffer containing test compound, blocker, and radioligand. The samples were incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2008
Entry Details Article
PubMed