BDBM22207 1,2,4-oxadiazole based compound, 24::1-({4-[5-(4-butylphenyl)-1,2,4-oxadiazol-3-yl]phenyl}methyl)azetidine-3-carboxylic acid

SMILES CCCCc1ccc(cc1)-c1nc(no1)-c1ccc(CN2CC(C2)C(O)=O)cc1

InChI Key InChIKey=QTKLDIPKJJAYHB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 22207   

TargetSphingosine 1-phosphate receptor 5(Human)
Merck Research Laboratories

LigandPNGBDBM22207(1-({4-[5-(4-butylphenyl)-1,2,4-oxadiazol-3-yl]phen...)
Affinity DataIC50: 2.40nMT: 2°CAssay Description:The assay measures the displacement of [33P]-labeled sphingosine-1-phosphate (S1P) by test compounds from human S1P receptors expressed on CHO cell m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2008
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
Merck Research Laboratories

LigandPNGBDBM22207(1-({4-[5-(4-butylphenyl)-1,2,4-oxadiazol-3-yl]phen...)
Affinity DataIC50: 2.90nMpH: 7.5 T: 2°CAssay Description:The assay measures the displacement of [33P]-labeled sphingosine-1-phosphate (S1P) by test compounds from human S1P receptors expressed on CHO cell m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2008
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 4(Human)
Merck Research Laboratories

LigandPNGBDBM22207(1-({4-[5-(4-butylphenyl)-1,2,4-oxadiazol-3-yl]phen...)
Affinity DataIC50: 350nMT: 2°CAssay Description:The assay measures the displacement of [33P]-labeled sphingosine-1-phosphate (S1P) by test compounds from human S1P receptors expressed on CHO cell m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2008
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
Merck Research Laboratories

LigandPNGBDBM22207(1-({4-[5-(4-butylphenyl)-1,2,4-oxadiazol-3-yl]phen...)
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:The assay measures the displacement of [33P]-labeled sphingosine-1-phosphate (S1P) by test compounds from human S1P receptors expressed on CHO cell m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2008
Entry Details Article
PubMed