BDBM22758 1-(2,3,4,5,6-pentachlorophenyl)-2-(2,3,4,5,6-pentafluorophenyl)ethane-1,2-dione::Benzil-based compound, 36

SMILES Fc1c(F)c(F)c(C(=O)C(=O)c2c(Cl)c(Cl)c(Cl)c(Cl)c2Cl)c(F)c1F

InChI Key InChIKey=LPUHARRFIWFXIH-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 22758   

TargetCoagulation factor XII(Human)
University of Mississippi

LigandPNGBDBM22758(1-(2,3,4,5,6-pentachlorophenyl)-2-(2,3,4,5,6-penta...)
Affinity DataKi:  380nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2008
Entry Details Article
PubMed
TargetLiver carboxylesterase 1(Rabbit)
University of Mississippi

LigandPNGBDBM22758(1-(2,3,4,5,6-pentachlorophenyl)-2-(2,3,4,5,6-penta...)
Affinity DataKi:  823nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2008
Entry Details Article
PubMed
TargetLiver carboxylesterase 1(Human)
University of Mississippi

LigandPNGBDBM22758(1-(2,3,4,5,6-pentachlorophenyl)-2-(2,3,4,5,6-penta...)
Affinity DataKi:  1.69E+3nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2008
Entry Details Article
PubMed
TargetLiver carboxylesterase 1(Human)
University of Mississippi

LigandPNGBDBM22758(1-(2,3,4,5,6-pentachlorophenyl)-2-(2,3,4,5,6-penta...)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of human carboxylesterase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Mississippi

LigandPNGBDBM22758(1-(2,3,4,5,6-pentachlorophenyl)-2-(2,3,4,5,6-penta...)
Affinity DataKi: >1.00E+5nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2008
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Mississippi

LigandPNGBDBM22758(1-(2,3,4,5,6-pentachlorophenyl)-2-(2,3,4,5,6-penta...)
Affinity DataKi: >1.00E+5nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2008
Entry Details Article
PubMed